Acaricidal, larvacidal, and repellent activity of Linalool loaded zinc oxide nanoparticles against Hyalomma anatolicum.

Current strategies for tick control have led to the development of resistance and environmental contamination. Consequently, there is an urgent need for research into new and effective acaricides for tick control. The aim of this study was to fabricate and characterize Linalool loaded zinc oxide nanoparticles (Lin@ZNP), and to assess the acaricidal, larvacidal, and repellent activities of Lin@ ZNP against Hyalomma anatolicum, a prevalent tick species infesting cattle in Saudi Arabia.

The Link Between Menopause and Urinary Incontinence: A Systematic Review.

This study aims to review the subsisting literature on the relationship between menopause and urinary incontinence (UI). To locate research that met the inclusion criteria, a thorough computerized search of relevant databases was carried out. A comprehensive search was carried out on PubMed, SCOPUS, Science Direct, Cochrane Library, and Web of Science to locate relevant material.

Potential use of silver nanoparticles green synthesized using Astragalus spinosus extract for treating cystic echinococcosis.

The present investigation aims to develop and evaluate silver nanoparticles (AgNP) synthesized through environmentally friendly methods and to assess their effectiveness against hydatid cysts through in vitro, ex vivo, and in vivo experiments. The green synthesis of ANP was accomplished using the precipitation technique with Astragalus spinosus extract. The in vitro protoscolicidal effects of ANP were evaluated on hydatid cyst protoscoleces (PTS) through eosin exclusion test.

Linalool-zinc oxide nanocomposite controls Toxoplasma gondii infection through inhibiting inflammation, oxidative stress, and pathogenicity.

The present in vitro and in vivo study aimed to fabricate and characterize linalool-zinc oxide nanoparticles (Lin-ZNP) and evaluate their effectiveness against Toxoplasma gondii infection in terms of inflammation, oxidative stress, and pathogenicity. Lin-ZNP was synthesized using an ethanolic solution of polyvinyl alcohol. The anti-Toxoplasma and cytotoxicity activities of Lin-ZNP were investigated, along with its effects on nitric oxide (NO) production, caspase-3 activity, and pro-inflammatory genes.

Child dental neglect and legal protections: a compendium of briefs from policy reviews in 26 countries and a special administrative region of China.

Background: Child neglect is a public health, human rights, and social problem, with potentially devastating and costly consequences. The aim of this study was to: (1) summarize the oral health profile of children across the globe; (2) provide a brief overview of legal instruments that can offer children protection from dental neglect; and (3) discuss the effectiveness of these legal instruments.

Methods: We summarized and highlighted the caries profile and status of implementation of legislation on child dental neglect for 26 countries representing the World Health Organization regions: five countries in Africa (Nigeria, South Africa, Sudan, Tanzania, Zimbabwe), eight in the Americas (Argentina, Brazil, Canada, Chile, Mexico, Peru, Unites States of America, Uruguay), six in the Eastern Mediterranean (Egypt, Iran, Libya, Jordan, Qatar, Saudi Arabia), four in Europe (Italy, Latvia, Serbia, United Kingdom), two in South-East Asia (India and Indonesia) and one country (China) with its special administrative region (Hong Kong) in the Western Pacific.

Aqueous Extract: A Promising Candidate for Hepatic Eimeriosis Treatment in Rabbits.

() is a common coccidian species that infects the liver and causes economic losses for the rabbit industry. This study aimed to determine the efficiency of green tea aqueous extract (GTE) as a natural treatment for eimeriosis caused by . Male rabbits .

Advancements in the Clinical Outcomes of Functional Neurosurgery With Deep Brain Stimulation for Movement Disorders: A Literature Review.

This literature review explores recent advancements in deep brain stimulation (DBS) surgery for movement disorders. It highlights notable improvements, including closed-loop stimulation techniques, optogenetics, and improved surgical targeting. Positive clinical outcomes with low complication rates and improved motor symptoms are consistently reported.

Synthesis, Characterization, DFT Studies of Novel Cu(II), Zn(II), VO(II), Cr(III), and La(III) Chloro-Substituted Schiff Base Complexes: Aspects of Its Antimicrobial, Antioxidant, Anti-Inflammatory, and Photodegradation of Methylene Blue.

A new chlorobenzylidene imine ligand, (E)-1-((5-chloro-2-hydroxybenzylidene)amino) naphthalen-2-ol (HL), and its [Zn(L)(NO)(HO)], [La(L)(NO)(HO)], [VO(L)(OCH)(HO)], [Cu(L)(NO)(HO)], and [Cr(L)(NO)(HO)], complexes were synthesized and characterized. The characterization involved elemental analysis, FT-IR, UV/Vis, NMR, mass spectra, molar conductance, and magnetic susceptibility measurements. The obtained data confirmed the octahedral geometrical structures of all metal complexes, while the [VO(L)(OCH)(HO)] complex exhibited a distorted square pyramidal structure.

Gender Differences Among Academic Radiation Oncology National Institutes of Health (NIH) Funding Recipients.

Purpose The purpose of our study was to evaluate National Institutes of Health (NIH) funding recipients between 2016 and 2019 to determine if there was an association between gender, research productivity, academic rank, leadership positions, and post-graduate awards. Materials and Methods The NIH Research Portfolio Online Reporting Tools Expenditure and Results (RePORTER) website was used to retrieve data for grants in Radiation Oncology from 2016-2019. Demographics and profiles of awardees were retrieved from institutional websites, LinkedIn, and Doximity.

Arabic Validity of the (CARE) Measure for Improving Medical and Mental Health Services.

Results: The majority of the item's responses showed high level of satisfaction. The coronach alpha of our study that examines the Arabic version of the CARE measurement tool 10 items was 0.96 showing an excellent internal consistency.

A Study of TaO Nanopillars with Ni Tips Prepared by Porous Anodic Alumina Through-Mask Anodization.

The paper discusses the formation of TaO pillars with Ni tips during thin porous anodic alumina through-mask anodization on Si/SiO substrates. The tantalum nanopillars were formed through porous masks in electrolytes of phosphoric and oxalic acid. The Ni tips on the TaO pillars were formed via vacuum evaporation through the porous mask.

Gender and Racial Profile of the Academic Pediatric Faculty Workforce in the United States.

Background Equity, diversity, and inclusion remain a challenge in the healthcare workforce. This study explored the current gender and racial/ethnic trends in academic pediatric positions across the United States. Methodology The pediatric faculty self-reported data by the American Association of Medical Colleges (AAMC) Faculty Roster from 2007 to 2020 were analyzed.

Level of anxiety among healthcare providers during COVID-19 pandemic in Saudi Arabia: cross-sectional study.

Background: The burden of the spread of the COVID-19 pandemic has impacted widely on the healthcare providers physically and mentally. Many healthcare providers are exposed to psychological stressors due to their high risk of contracting the virus.

Aims: This study aimed to measure the level of anxiety among healthcare providers during the COVID-19 pandemic in Saudi Arabia.

Synthesis, spectral characterization, DFT calculations, pharmacological studies, CT-DNA binding and molecular docking of potential N, O-multidentate chelating ligand and its VO(II), Zn(II) and ZrO(II) chelates.

The pharmacological efficacy of the variety tetradentate ligands encouraged us to design attractive compounds through effective synthetic procedure. The prepared Schiff base ligand 6,6'-((1E,1'E)-((4-chloro-1,2-phenylene)bis(azaneylylidene))bis(methaneylylidene))bis(2-ethoxy phenol (HL), which derived from 4-chloro-o-phenylenediamine and 3-ethoxy-salicylaldehyde and its VO(II), Zn(II) and ZrO(II) metal chelates, have been synthesized and characterized with aim of that it may struggle the invasion of drug resistance. The chemical structural of studied compounds were discussed by TGA, elemental analysis, UV-Vis.

The impact of COVID-19 pandemic on the level of depression among health care workers: cross-sectional study.

Background: The outbreak of the novel Corona Virus Infectious Disease 2019 (COVID-19) has spread rapidly to many countries leading to thousands of deaths globally. The burden of this pandemic has affected the physical and mental health of the frontline health care workers (HCWs) who are exposed to high risk of infection and psychological stressors.

Aims: The aim is to measure the level of depression among healthcare workers in Saudi Arabia during COVID-19 pandemic to establish interventional strategies.

Application of triazoles as bioisosteres and linkers in the development of microtubule targeting agents.

The triazole ring system has emerged as an exciting prospect in the optimization studies of promising lead molecules in the quest for new drugs for clinical usage. Several marketed drugs possess these versatile moieties that are used in a wide range of medical indications. This stems from the unique intrinsic properties of triazoles, which impart stability to the basic pharmacophoric unit with an added advantage of being a bioisostere of different chemical functionalities.

Manuscript Writing and Publication Workshop: An Invoking Pilot Study on Enhancing Cognitive Research Capabilities in Health Sciences Institutes of Pakistan.

Background With an upsurge in research in developing countries, researchers from allied sciences need to augment their skills for disseminating research work worldwide. Training workshop is one of the quick interventions which can enhance writing skills and ease research publication. Objective We designed this research to explore the perception of the faculty of different higher education institutes (HEIs) regarding manuscript writing and to assess the impact of these workshops in the improvement of cognitive capabilities of preliminary researchers in Pakistan.

Dietary intake assessment of pyrethroid residues from okra and eggplant grown in peri-urban areas of Punjab, Pakistan.

This study was designed to assess the gradual increase in the use of insecticides on vegetables and to familiarize the consumers regarding the insecticide residues. The purpose of this research work was to highlight the detrimental effects of pyrethroids (bifenthrin, cyfluthrin, cypermethrin, deltamethrin, fenvalerate, lambda-cyhalothrin, and permethrin) compare with dietary intake assessment of eggplant and okra grown in peri-urban environment. In this manner, a total of 180 (n = 60 × 3) samples of eggplant (Solanum melongena) and okra (Abelmoschus esculentus) were procured from the peri-urban farming system of Faisalabad, Multan, and Gujranwala to assess the pyrethroid residues along with their dietary intake assessment.

The effectiveness of bismuth breast shielding with protocol optimization in CT Thorax examination.

Background: Numerous techniques had been proposed to reduce radiation exposure in computed tomography (CT) including the use of radiation shielding.

Objective: This study aims to evaluate efficacy of using a bismuth breast shield and optimized scanning parameter to reduce breast absorbed doses from CT thorax examination.

Methods: Five protocols comprising the standard CT thorax clinical protocol (CP1) and four modified protocols (CP2 to CP5) were applied in anthropomorphic phantom scans.

Developmental lead (Pb)-induced deficits in hippocampal protein translation at the synapses are ameliorated by ascorbate supplementation.

Background: Lead (Pb) is a persistent environmental neurotoxin and its exposure even in minute quantities has been known to induce neuronal defects. The immature brain is singularly sensitive to Pb neurotoxicity, and its exposure during development has permanent detrimental effects on the brain developmental trajectory and neuronal signaling and plasticity, culminating into compromises in the cognitive and behavioral attributes which persists even later in adulthood. Several molecular pathways have been implicated in the Pb-mediated disruption of neuronal signaling, including elevated oxidative stress, alterations in neurotransmitter biology, and mitochondrial dysfunction.

Brain metastasis and herniation in a patient with ampullary adenocarcinoma presenting with jaundice and memory loss: case report.

Periampullary carcinoma includes neoplasms arising from head of pancreas, distal common bile duct, duodenum and ampulla of Vater. We report a case of a 41-year-old male, medically free who presented to our hospital as a case of obstructive jaundice, weight loss, headache and blurred vision. Clinical evaluation revealed memory loss and ataxia.

Herbert Cannulated Bone Screw Osteosynthesis in Anterior Mandibular Fracture Treatment: A Comparative Study With Lag Screw and Miniplate.

Purpose: The Herbert bone screw (HBS) is a successful and minimally invasive method of fracture fixation that is used routinely in orthopedic surgery. The aim of this study was to evaluate the clinical and radiographic performances of the HBS in the treatment of anterior mandibular fractures and compare it with the common and established treatment modalities, the lag screw (LS) and the 2.0-mm miniplate (MP).

Effects of sunitinib targeted chemotherapy on the osseointegration of titanium implants.

Targeted chemotherapies are novel therapeutic approaches for many malignancies. In contrast to conventional chemotherapies, which are given for a predetermined duration, treatment with targeted chemotherapies like sunitinib is routinely continuous over longer periods, sometimes years. During this prolonged treatment period, patients may need to restore their missing teeth with dental implants.

Environmental impacts of heavy metals, rare earth elements and natural radionuclides in marine sediment from Ras Tanura, Saudi Arabia along the Arabian Gulf.

Ras Tanura city is one of the most important cities in Saudi Arabia because of the presence of the largest and oldest oil refinery in the Middle East which was began operations in September 1945. Also its contains gas plant and two ports. The concentration of natural radionuclides, heavy metals and rare earth elements were measured in marine sediment samples collected from Ras Tanura.