Updates in lung isolation techniques.

Innovations and challenges for lung separation or isolation have evolved during the last few years. In this chapter, we present the up-to-date, robust evidence available during the previous five years supporting the positions of the different devices, techniques, and tricks for their use in adult and pediatric patients undergoing various thoracic surgical interventions. Additionally, we presented an update on lung isolation in patients with airway difficulty and the suggested training level to master these techniques.

Biosorbent silver nanoparticles decorated coffee-ground waste composite for cleaning water and antimicrobial applications.

A sustainable biosorbent, silver nanoparticles-decorated coffee-ground waste (CWAg), was synthesized through a simple in-situ reduction method. CWAg is extensively characterized via SEM-EDX, PZC, FTIR, XRD, HR-TEM, and XPS analyses. The biosorbent was tested to remove chromium (Cr(VI)) and methylene blue (MB) from wastewater, and its antibacterial properties was evaluated.

Unraveling the threads of depressive symptoms: Enhancing predictions of depression among university junior students.

Background: The mental burden faced by university students in their early years is not frequently reported in the literature.

Objectives: The aim of this study is to investigate the prevalence and predictors of depression among preparatory (first) year university students using a predictive test developed from general health and well-being questionnaires.

Methods: A cross-sectional study was conducted among university students in the eastern region of Saudi Arabia from March 2023 to June 2023.

Exploring the Impact of Digital Health Tools in Enhancing Quality of Life and Psychological Adjustment in Long-term Blood Donors: A Cross-Sectional Study.

Background: Blood donation plays a critical role in public health, yet long-term donors (donating at least twice per year, for at least three years) often face challenges related to psychological adjustment and quality of life. Digital health tools could offer innovative solutions to address these issues by providing personalized support, tracking, and mental health interventions.

Aim: This study investigates the impact of digital health tools on the quality of life (QoL) and psychological adjustment of long-term blood donors in Saudi Arabia, with attention to demographic factors influencing engagement and perceptions.

Immunomodulatory Roles of Mesenchymal Stem Cell-derived Extracellular Vesicles: A Promising Therapeutic Approach for Autoimmune Diseases.

Autoimmune diseases pose a significant challenge due to their complex pathogenesis and rising prevalence. Traditional therapies are often limited by systemic side effects, immunosuppression, and lack of long-term efficacy. Mesenchymal stem cells (MSCs) have demonstrated immunomodulatory properties, primarily through the secretion of extracellular vesicles (EVs), which are now recognized as potent mediators of immune regulation.

Performance of the ChatGPT-3.5, ChatGPT-4, and Google Gemini large language models in responding to dental implantology inquiries.

Statement Of Problem: Artificial intelligence (AI) chatbots have been proposed as promising resources for oral health information. However, the quality and readability of existing online health-related information is often inconsistent and challenging.

Purpose: This study aimed to compare the reliability and usefulness of dental implantology-related information provided by the ChatGPT-3.

Influence of 3D printing orientations on physico-mechanical properties and accuracy of additively manufactured dental ceramics.

Purpose: This systematic review aims to assess the impact of different 3D printing orientations on the physico-mechanical properties, volumetric change, and accuracy of additively manufactured ceramic specimens, as well as their restorations.

Study Selection: The web database containing records for building orientation of 3D-printed ceramics until January 2024 was searched, with no language limitations. PRISMA 2020 guidelines were followed, and the risk of bias was evaluated using the modified CONSORT checklist for laboratory studies on dental materials.

Influence of different print orientations on properties and behavior of additively manufactured resin dental devices: A systematic review and meta-analysis.

Statement Of Problem: Different factors affect 3-dimensionally (3D) printed resin products. However, evidence on the effect of the print orientation on resin dental devices is lacking.

Purpose: The purpose of this systematic review and meta-analysis was to assess the impact of print orientation on the properties and accuracy of 3D printed implant surgical guides, occlusal devices, clear orthodontic retainers, and aligners.

Insights on the Mesembryanthemum forsskalii phenotype and study of the effects of several exogenous plant growth regulators via plant tissue culture.

Background: Samh (Mesembryanthemum forsskalii, M. cryptanthum) belongs to Aizoaceae family and is found in northern Saudi Arabia, primarily in desert or dry shrubland habitats. M.

HPO promoted reactions of thioamides with 2-substituted benzyl alcohols.

In this study, we have investigated the reactivity of thioamides with alcohols by utilizing HPO as a low-toxicity, cost-effective Brønsted acid catalyst. This report includes a methodology for the synthesis of thioesters from thioamides and 2-hydroxyaryl alcohols. Thioesters are emerging as a notable class of organic molecules due to their biological relevance, extensive use in drug discovery, and industrial applications.

C-reactive protein (CRP) levels in people with eating disorders: A systematic review and meta-analysis.

Studies suggest that there is a relationship between inflammatory diseases, inflammatory markers such as C-reactive protein (CRP) and psychiatric disorders. In eating disorders, cross-sectional studies have recently examined peripheral CRP levels in blood serum and plasma, which allow a comprehensive meta-analysis. This systematic review and meta-analysis examined studies from three databases, measuring CRP levels in people with eating disorders, following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines.

Assessing the Causes of Acceptance or Refusal of Breast Cosmetic Procedures Among Saudi Women When They Get to Age of Menopause: A Cross Sectional Study-Saudi Arabia.

Introduction: Cosmetic breast surgery encompasses a variety of procedures aimed at enhancing breast appearance and is increasingly popular globally. Despite this trend, the acceptance of such surgeries among Saudi women approaching menopause remains understudied. This research aims to explore the attitudes and perceptions toward cosmetic breast surgery in this demographic, considering cultural and religious influences in Saudi Arabia.

Efficacy of Duloxetine for Postspine Surgery Pain: A Systematic Review and Meta-Analysis.

Background: Duloxetine, a serotonin and norepinephrine reuptake inhibitor (SNRI), is used to treat various health conditions, including major depressive disorder, generalized anxiety disorder, fibromyalgia, and off-label for chemotherapy-induced pain. We conducted this systematic review and meta-analysis aiming to test the current evidence regarding effectiveness and safety of duloxetine for postspine surgeries pain.

Methods: We searched the Cochrane Central Register of Controlled Trials, PubMed, Scopus and Web of science databases for relevant articles up to March 2024.

RAP-2 and CNH-MAP4 Kinase MIG-15 confer resistance in bystander epithelium to cell-fate transformation by excess Ras or Notch activity.

Induction of cell fates by growth factors impacts many facets of developmental biology and disease. LIN-3/EGF induces the equipotent vulval precursor cells (VPCs) in to assume the 3˚-3˚-2˚-1˚-2˚-3˚ pattern of cell fates. 1˚ and 2˚ cells become specialized epithelia and undergo stereotyped series of cell divisions to form the vulva.

Managing Early Childhood Caries: A Comparative Review of Preventive and Restorative Approaches.

Early childhood caries (ECC), one of the most common health problems among children aged six years and below, is considered present when one or more surfaces of a tooth are decayed, missing, or filled. Not only does ECC cause pain for a long time, but it also has short- and long-term health consequences in children. In order to treat ECC, holistic management that includes preventive, restorative, and prosthetic intervention is necessary.

Barriers and Facilitators to Colorectal Cancer Screening: Providers' Perspective.

Background: Colorectal cancer ranks as the third most prevalent cancer worldwide and the second most prevalent cancer in Saudi Arabia. Additionally, it stands as the second leading cause of cancer-related mortality globally. There is an increasing incidence of colorectal cancer worldwide.

Gallic Acid: A Potent Metabolite Targeting Shikimate Kinase in .

is a highly multidrug-resistant pathogen resistant to almost all classes of antibiotics; new therapeutic strategies against this infectious agent are urgently needed. Shikimate kinase is an enzyme belonging to the shikimate pathway and has become a potential target for drug development. This work describes the search for Food and Drug Administration (FDA)-approved drugs and natural compounds, including gallic acid, that could be repurposed as selective shikimate kinase inhibitors by integrated computational and experimental approaches.

Virtual Versus Traditional Learning: A Comparison of Dental Students' Perception and Satisfaction.

Comparing the effectiveness of virtual and traditional learning methods is crucial for understanding their impact on knowledge transmission in different subjects. The objective of this cross-sectional study was to explore dental students' perceptions and satisfaction levels with their experiences in virtual learning compared to traditional classroom learning. A cross-sectional survey was administered to all dental students in the College of Dentistry across preclinical (3rd and 4th year) and clinical (5th and 6th year) levels using Google Forms.

Dental Practitioners' Knowledge and Attitudes Toward the Etiology, Diagnosis, and Treatment of Peri-Implantitis.

The objective of this study was to assess the level of knowledge and attitude about the etiology, diagnosis, and management of peri-implantitis among dental practitioners. An online cross-sectional study on 303 dentists in Saudi Arabia was conducted. A closed-ended survey consisting of 28 questions was designed.

Internal and marginal fits of 3D-printed provisional prostheses: comparative effect of different printing parameters.

Objectives: The influence of printing parameters on the marginal and internal fit of three-dimensional (3D) printed interim fixed partial dentures (IFPDs) has been understudied. This investigation sought to elucidate the impact of printing orientation and post-curing time on these critical factors.

Methods: A total of 260 3-Unit IFDPs were printed using two different resins (130/NextDent C&B MFH and 130/ASIGA DentaTOOTH).

Marginal zone lymphoma of mucosa associated lymphoid tissue-lymphoma of the lacrimal gland in a young patient with Klinefelter syndrome: a case report.

Background: Klinefelter syndrome is considered one of the most common sex chromosome disorders affecting males. The presence of an extra X chromosome can alter the tendency to develop various cancers, including lymphomas. Lacrimal gland lymphoma is a disease of the elderly, with a median age of presentation of 70 years.

Impact of 3D printing orientation on accuracy, properties, cost, and time efficiency of additively manufactured dental models: a systematic review.

Background: The evidence on the effect of printing orientation on dimensional accuracy and properties of resinous dental models is unclear. This systematic review aimed to assess the impact of printing orientation on the accuracy and properties of additively manufactured resinous dental models, besides the cost, material consumption, and time efficiency at different orientations.

Methods: A comprehensive web search (PubMed, Scopus, Cochrane) was performed in July 2024 without language restrictions.

Factors Affecting Vancomycin Trough Concentration; a Population Pharmacokinetic Model in Non-Critical Care Saudi Patients.

Background And Objective: Vancomycin is commonly prescribed in treatment of methicillin-resistant Staphylococcus aureus infections. While, vancomycins' pharmacokinetic vary among older patients, there is a paucity of data regarding specific characteristics influencing pharmacokinetics in Saudi adult patients. This study aims to establish a population-pharmacokinetic (Pop-PK) model for vancomycin in patients admitted to medical wards, with the focus on identification of patient characteristics influencing vancomycin trough concentrations.