Occupational Exposure to Sharp Object Injuries Among Healthcare Workers in Dammam and Jeddah Hospitals, Saudi Arabia‏.

Objective: This study identify the prevalence of sharp object injuries (SOIs) among healthcare workers (HCWs) in Dammam and Jeddah, Saudi Arabia.

Methods: Quantitative methodology using a cross-sectional design was applied. Chi-square testing was employed for comparative analyses, and logistic regression encompassing univariate and multivariate models was implemented to ascertain the predictors of SOIs.

Comparative assessment of three AI platforms in answering USMLE Step 1 anatomy questions or identifying anatomical structures on radiographs.

The application of artificial intelligence (AI) in education has gained great attention recently. Integration of AI tools in anatomy teaching is currently engaging researchers and academics worldwide. Several AI chatbots have been generated, the most popular being ChatGPT (OpenAI: San Francisco, California, USA).

Minimizing Blood Loss Using Tranexamic Acid in Patients Undergoing Liposuction: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Background: Liposuction has become the most sought-after aesthetic surgery across the globe, increasing the demand for more developments in patient safety protocols. Evidence of the efficacy of tranexamic acid (TXA) in reducing intraoperative blood loss with minimal complications have led to its widespread applications across various surgical operations. However, the role and effectiveness of TXA in liposuction is not fully understood.

Exercise intensities and metabolic health: Targeting blood glucose, insulin, and C-peptide levels in adults with prediabetes in the postprandial state.

Objective: Exercise improves postprandial glycaemia and insulin sensitivity in individuals with prediabetes, but the optimal intensity for this metabolic regulation remains unclear. The current study aims to explore the impact of various exercise intensities on metabolic markers in prediabetic individuals to identify the optimal intensity for improving these indicators.

Methods: In this crossover study, 25 prediabetic individuals participated in exercise sessions at 50 %, 60 %, 70 %, and 80 % intensities of their predicted maximum heart rate using a treadmill.

Lifestyle Intervention Improves Parasympathetic Activity in Hypertrophic Cardiomyopathy.

Unlabelled: Background A limited number of studies have investigated the effects of lifestyle interventions in hypertrophic cardiomyopathy (HCM). This study evaluated the effect of a novel lifestyle intervention incorporating physical activity (PA) and dietary nitrate supplementation on heart rate variability (HRV) and haemodynamic measures in HCM.

Methods: Twenty-eight individuals with HCM were randomised into either the intervention or control group.

A rare case of traumatic reticulopericarditis in camel ().

Background: Traumatic reticulopericarditis (TRP) is rarely reported in camels. This report provides TRP in camels.

Case Description: She-camel (3 years old) with a history of anorexia, and stinky smell-bloody diarrhea for more than 3 weeks associated with pain, ventral thoracoabdominal edema, positive for metal detection examination that raised the suspicion of TRP.

Green synthesis, characterization, morphological diversity, and colorectal cancer cytotoxicity of gold nanoparticles.

The synthesis of gold nanoparticles (AuNPs) green methods is advantageous due to their economic viability, reduced environmental pollution, and safety towards human health. According to our best knowledge, there is limited documented research on synthesizing AuNPs using gum Arabic (GA) and cinnamon (CNM) and studying their anticancer activities against colorectal cancer cells. This study presents a simple approach to synthesizing AuNPs using GA and CNM, characterized by advanced analytical techniques, including UV-Vis and FTIR spectroscopies, SEM, EDS, TEM, SAED, Zeta sizer, and Zeta potential.

A Systematic Review and Meta-Analysis of Prehospital Plasma Administration for Hemorrhagic Shock.

Introduction: Hemorrhagic shock demands swift intervention. Management involves the rapid infusion of blood products to restore circulation and uphold tissue perfusion. The aim of this study was to evaluate the effectiveness of prehospital plasma administration in trauma patients, comparing outcomes with normal saline.

The interplay between toothbrush stiffness and charcoal-containing dentifrice on the development of enamel topography changes.

Background: This study aimed to investigate the in vitro effect of a charcoal-containing dentifrice with different toothbrush stiffness on enamel.

Methods: Four main groups were applied: distilled water, conventional fluoridated toothpaste (Colgate Total 12 Clean Mint Toothpaste), charcoal toothpaste (Colgate Total Charcoal Toothpaste) and whitening toothpaste (Colgate Total Advanced Whitening Toothpaste). Three subgroups for each toothpaste were further included according to the toothbrush bristles' stiffness (soft, medium, and hard).

Evaluation of different inflammatory markers during the infection of domestic cats (Felis catus) by Cystoisospora felis (Coccidia: Apicomplexa).

Background: Cystoisospora felis or Isospora felis is a ubiquitous apicomplexan protozoon parasite infecting domestic cats worldwide.

Objectives Of The Study: this study aims to identify the causative agent of diarrhea in cats by determining several elevating stressors caused by these coccidian protozoans with molecular characterization. So, from January 2023 to April 2023, a total of 370 domestic cats were hospitalized at various clinics in the Cairo and Giza Governorates.

Meta-Analysis Investigating Optimal Timing of Chemoprophylaxis for Venous Thromboembolism in Operatively Managed Blunt Spinal Injuries.

Background: Blunt spinal injuries (BSIs) are associated with substantial morbidity and mortality. Management typically involves stabilization of the spinal column and may include chemoprophylaxis for venous thromboembolism (VTE) prevention. The optimal timing of chemoprophylaxis initiation in operatively managed BSI patients remains debated.

Achievement of No Evidence of Disease Activity-3 with Oral Disease-Modifying Treatment in Patients with Relapsing-Remitting Multiple Sclerosis.

Background: There is scant data regarding the use of oral disease-modifying treatments (oDMT) in patients with relapsing-remitting multiple sclerosis (PwRRMS) from Saudi Arabia.

Objective: This study aimed to identify the response rate to oDMT in PwRRMS compared to interferon (IFN) in terms of achieving no evidence of disease activity-3 (NEDA-3).

Methods: This retrospective study was conducted at a tertiary care hospital in Saudi Arabia and included all adult PwRRMS over a 2-year period who were on oDMTs or IFN for <1 year.

Preterm Infant Enteral Feeding Practices in Saudi Arabia: A Scoping Review.

Background: Preterm infants are at risk of developing nutritional deficiencies, which is further compounded by the fact that providing them with adequate nutrition is often challenging. Enteral feeding (EF) practices vary across neonatal units and can be impacted by the setting and geographical region. There is also a lack of evidence on best practices.

Microalbuminuria in Children With Sickle Cell Disease in the Eastern Province of Saudi Arabia.

Background And Objective: Sickle cell disease (SCD) complications, such as sickle cell nephropathy (SCN), may begin in childhood and progress insidiously to chronic kidney disease in adulthood. In Saudi Arabia (SA), there is a lack of studies evaluating kidney function in children with SCD. This study aims to assess microalbuminuria (MA) as an early marker of renal dysfunction in SCD children living in the Eastern region of SA, to potentially institute appropriate early treatment.

Biogenically synthesized gold nanocarrier ameliorated antiproliferative and apoptotic efficacy of doxorubicin against lung cancer.

Introduction: Conventional chemotherapy treatment is commonly linked to significant side effects due to high therapeutic doses. In this regard, nanoformulations with chemotherapeutic medications hold promise in enhancing drug effectiveness through the reduction of therapeutic dosages, thereby mitigating the potential for adverse side effects. Because of numerous applications in the biomedical arena, there has been a rising interest in developing an environmentally acceptable, long-lasting, and affordable technique for the production of gold nanoparticles.

Impact of printing layer thickness on the flexural strength of nanocomposite 3D printed resins: An in vitro comparative study.

Background: This study evaluated the influence of various printing layer thicknesses with silicon dioxide nanoparticles (SiONPs) incorporated as a reinforcement material on the flexural strength of 3D-printed denture base resins.

Material And Methods: Asiga (DentaBASE, Asiga, Erfurt, Germany) and NextDent (Denture 3D+, NextDent B.V.

Flourishing levels among health and non-health profession students in Saudi Arabian colleges.

Objectives: This study aimed to evaluate the levels of flourishing among university students, compare these levels between students in health-related and non-health-related colleges, and identify factors that predict flourishing.

Methods: A cross-sectional study was conducted at Imam Abdulrahman Bin Faisal University, Saudi Arabia, involving 1,148 students from the first to fourth year across both academic sectors. Data were collected utilizing the self-reported Global Flourishing Study Questionnaire (GFS) during the period from September 2023 to June 2024.

Synthesis and antiproliferative activity of 2-oxo-3-phenylquinoxaline derivatives and related compounds against colon cancer.

We have designed 17 new 2-oxo-3-phenylquinoxalines the chemoselective Michael reaction of 3-phenylquinoxalin-2(1)-one with acrylic acid derivatives. The ester, ethyl 3-(2-oxo-3-phenylquinoxalin-1(2)-yl)propanoate, was reacted with hydroxylamine and hydrazine to produce -hydroxy-3-(2-oxo-3-phenylquinoxalin-1(2)-yl)propanamide and hydrazide, respectively. Further modifications were made through reactions with isothiocyanates and azide coupling with amines, yielding thiosemicarbazides and -alkyl derivatives.

Radiomic features based automatic classification of CT lung findings for COVID-19 patients.

. The lung CT images of COVID-19 patients can be typically characterized by three different findings- Ground Glass Opacity (GGO), consolidation and pleural effusion. GGOs have been shown to precede consolidations and has different heterogeneous appearance.

Synthesis of arylated tetrahydrobenzo[]quinoline-3-carbonitrile derivatives as potential hits for treatment of diabetes.

Quinoline scaffolds are serving as the core structure for numerous antifungal, analgesic, antipyretic, anti-inflammatory drugs as well as have also been investigated for their potential antidiabetic properties. Though further exploration is required in this area as the current antidiabetic agents, such as acarbose, miglitol and voglibose, are associated with several adverse side effects. In this context, arylated tetrahydrobenzo[]quinoline-3-carbonitrile derivatives were designed and evaluated as potential antidiabetic agents.

Impact of a Mobile, Cloud-Based Care-Coordination Platform on Door-to-Balloon Time in Patients With STEMI: Initial Results.

Care-coordination platforms may optimize ST-elevation myocardial infarction (STEMI) treatment delays. This study aimed to assess the impact of Stenoa use on treatment delays in STEMI patients. We conducted a retrospective cohort study on local STEMI cases for the period between September 2020 and March 2023, comparing the times from first medical contact to device, before vs after the implementation of the Stenoa platform by the catheterization laboratory (cath-lab) and emergency department.

An Overview of Commonly Used Natural Alternatives for the Treatment of Androgenetic Alopecia, with Special Emphasis on Rosemary Oil.

Androgenetic alopecia is a chronic dermatological condition in which genetically predisposed individuals undergo progressive hair loss secondary to the effects of circulating androgens. It has been well documented that dihydrotestosterone binds to the androgenic receptors prevalent in the scalp, thus inducing miniaturization of the hair follicle. To date, the only FDA approved medications for the treatment of androgenetic alopecia are finasteride and minoxidil.

Gut fungal profile in new onset treatment-naïve ulcerative colitis in Saudi children.

Background: Although the role of fungi in gut inflammation in IBD has been suggested, data are still limited in ulcerative colitis (UC). Our aim was to describe the gut fungal profile in a pediatric UC in Saudi Arabia.

Methods: Fecal samples from children with UC and control samples provided by healthy school children were collected.