Hybrid Functional Near-Infrared Spectroscopy System and Electromyography for Prosthetic Knee Control.

The increasing number of individuals with limb loss worldwide highlights the need for advancements in prosthetic knee technology. To improve control and quality of life, integrating brain-computer communication with motor imagery offers a promising solution. This study introduces a hybrid system that combines electromyography (EMG) and functional near-infrared spectroscopy (fNIRS) to address these limitations and enhance the control of knee movements for individuals with above-knee amputations.

Effect of daily immersion of different beverages on the surface roughness and color stability of 3D-printed denture base resins.

Purpose: To measure the effect of daily immersion in varying beverages (distilled water, tea, carbonated beverage, and orange juice) on surface roughness and color stability of 3D-printed denture base resins.

Materials And Methods: 160 acrylic resin discs (15 × 2.5 mm) were made from heat-polymerized (HP), and 3D-printed resins (FormLabs, ASIGA, and NextDent).

Influence of steel-to-concrete ratio on sustainable column design in Saudi Arabia.

This study investigates the impact of the steel-to-concrete ratio in building columns on environmental factors, embodied energy, and cost estimations in a hotel construction scenario in the Eastern Province of Saudi Arabia. This study focuses on the production (A1-A3) and construction (A4-A5) stages, omits the use and disposal phases, and extensively examines the material components and their environmental implications. It evaluates the environmental impact of diverse column types.

Trimesic Acid as a Building Block for Ternary and Quaternary Salts and Salt Cocrystals.

In the field of cocrystals, the synthon-based design of two-component crystals is well established and the interest is now shifting toward higher order cocrystals as the next challenge. Carboxylic acids form a robust synthon with pyridyl coformers and interact with 2-aminopyrimidines through a pair of strong, charge-assisted hydrogen bonds. In this work we describe the formation of higher order salts and salt cocrystals of trimesic acid using 2,4-diaminopyrimidine (pyrimethamine, trimethoprim) and pyridyl (4,4'-bipyridine, 1,2-di(4-pyridyl)ethylene, 1,3-di(4-pyridyl)propane, 4-phenylpyridine) coformers.

Impact of Digital Workflow Integration on Fixed Prosthodontics: A Review of Advances and Clinical Outcomes.

The field of prosthodontics has seen substantial advancements with the integration of digital workflows, which have revolutionized traditional clinical practices. These digital technologies, including intraoral scanners (IOS), computer-aided design (CAD), and computer-aided manufacturing (CAM), have enhanced the precision, efficiency, and overall quality of prosthetic restorations. This review explores the clinical outcomes of adopting digital workflows in prosthodontics, with a focus on their impact on accuracy, time efficiency, and patient satisfaction.

Oncocytic lipoadenoma of the parotid gland: a case report and a review of the literature.

Oncocytic lipoadenomas are a rare sub-category of fat-containing tumors of the salivary glands. These tumors are characterized by their oncocyte-predominant epithelial component admixed with mature adipocytes. This condition has been rarely reported to affect the parotid and the submandibular glands.

Deprescribing anticholinergics to preserve brain health: reducing the risk of dementia through deprescribing (R2D2): study protocol for a randomized clinical trial.

Background: Older adults commonly experience chronic medical conditions and are at risk of cognitive impairment as a result of age, chronic comorbidity, and medications prescribed to manage multiple chronic conditions. Anticholinergic medications are common treatments for chronic conditions and have been repeatedly associated with poor cognitive outcomes, including delirium and dementia, in epidemiologic studies. However, no study has definitively evaluated the causal relationship between anticholinergics and cognition in a randomized controlled trial design.

Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C).

Multisystem inflammatory syndrome in children (MIS-C) is a rare condition following SARS-CoV-2 infection associated with intestinal manifestations. Genetic predisposition, including inborn errors of the OAS-RNAseL pathway, has been reported. We sequenced 154 MIS-C patients and utilized a novel statistical framework of gene burden analysis, "burdenMC," which identified an enrichment for rare predicted-deleterious variants in BTNL8 (OR = 4.

Cochlear Implantation: Predicting Round Window Niche Visibility Using One Measurement in High-Resolution Temporal Bone Computed Tomography.

Background: To evaluate the accuracy of a single measurement in temporal bone computed tomography in predicting the round window niche (RWN) visibility during cochlear implantation.

Methods: A prospective study was conducted on 148 patients (165 ears) who had a cochlear implant (CI) from January 2010 to December 2018 at a tertiary CI center. The measurement was done for the angle of the basal turn of the cochlea (ABTC), which we defined as the angle formed by the cochlear basal turn and the cranium mid-sagittal plane, by 2 readers blindly from the axial images of computed tomography.

Deprescribing Anticholinergics to Preserve Brain Health: Reducing the Risk of Dementia through Deprescribing (R2D2): Study Protocol for a Randomized Clinical Trial.

Background: Older adults commonly experience chronic medical conditions and are at risk of cognitive impairment as a result of age, chronic comorbidity, and medications prescribed to manage multiple chronic conditions. Anticholinergic medications are common treatments for chronic conditions, and have been repeatedly associated with poor cognitive outcomes, including delirium and dementia, in epidemiologic studies. However, no study has definitively evaluated the causal relationship between anticholinergics and cognition in a randomized controlled trial design.

Cross-Cultural Adaptation and Validation of Foot and Ankle Ability Measure (FAAM) for Arabic-Speaking Patients.

Background: The original English Foot and Ankle Ability Measure (FAAM) is widely adopted to track changes in foot and ankle function. The aim of this study is to translate it to an Arabic version of FAAM (FAAM-A), and then to assess the validity and reliability of the FAAM-A version.

Methodology: One hundred five consecutive Arabic-speaking participants with different foot and ankle pathologies completed the FAAM-A.

Faculty Members' Perception, Implementation, and Challenges of Formative Assessment in Undergraduate Medical Education: A Cross-Sectional Study.

Background: Medical curriculum reform requires quality assurance in all curricular activities including assessment. Such reform necessitates a shift of focus from summative assessment (SA) to formative assessment (FA). However, the implementation of FA confronts several challenges that hinder its proper application, especially with the increased number of students and the diversity of activities required from faculty members.

A comparative study of strength and surface properties of permanent 3D-printed resins with CAD-CAM milled fixed dental prostheses.

Purpose: To compare the strength, surface roughness, and hardness of newly introduced permanent three-dimensional (3D)-printed resin in comparison with computer-aided design and computer-aided manufacturing (CAD-CAM) milled materials.

Materials And Methods: Three 3D-printed resins (NextDent C&B, Formlabs Permanent Crown, and VarseoSmile Crown plus) and two CAD-CAM milled (IPS e.max ZirCAD LT and VITA Enamic) resins were used to fabricate discs specimens.

Molecular modeling and synthesis of novel benzimidazole-derived thiazolidinone bearing chalcone derivatives: a promising approach to develop potential anti-diabetic agents.

Diabetes mellitus (DM) is a disorder which is raised at the alarming level and it is characterized by the hyperglycemia results from the impaired action of insulin, production of insulin or both of these simultaneously. Consequently, it causes problems or failure of different body organs such as kidneys, heart, eyes, nerve system. Since this disease cannot be completely cured until now, we aimed to design series of enzymes inhibitors and tested them for DM treatment.

Functional outcome predictors and recanalization in cerebral venous thrombosis: A single-center cross-sectional study.

Objectives: Cerebral venous thrombosis (CVT) is a rare type of stroke. Functional outcome (FOC) in CVT can be affected by different factors, and recanalization is an important determinant. This study aimed to identify the FOC predictors including recanalization in patients with CVT.

Examining the growing challenge: Prevalence of diabetes in young adults (Review).

Diabetes is rapidly spreading worldwide, affecting millions of individuals. Therefore, it is crucial to have a comprehensive understanding of its complications. The present review discusses the complex subject of diabetes, including the type 1 and type 2 variants.

Effect of Zinc on improving silver diamine fluoride-derived tooth discoloration in vitro.

Background: Silver Diamine Fluoride (SDF) is effective for arresting dental caries, presenting a valuable non-invasive treatment option in dentistry. Despite its therapeutic advantages, a significant drawback is the tooth discoloration that follows its application, which can affect patient acceptance. Addressing this aesthetic concern without diminishing the treatment's efficacy remains challenging in dental practice.

Accuracy of repaired maxillary dentures from two different repairing techniques: In vitro study.

Background: Denture fracture is a common problem with acrylic dentures. The fractured denture can be repaired using various techniques such as self-cure acrylic resin acrylic resin and fiber-reinforced acrylic resin.

Purpose: The purpose of this study was to compare the accuracy of dentures repaired with self-cure acrylic resin and fiber-reinforced acrylic resin processed using two different techniques (long-cure and microwave processing).

Occupational Exposure to Sharp Object Injuries Among Healthcare Workers in Dammam and Jeddah Hospitals, Saudi Arabia‏.

Objective: This study identify the prevalence of sharp object injuries (SOIs) among healthcare workers (HCWs) in Dammam and Jeddah, Saudi Arabia.

Methods: Quantitative methodology using a cross-sectional design was applied. Chi-square testing was employed for comparative analyses, and logistic regression encompassing univariate and multivariate models was implemented to ascertain the predictors of SOIs.

Comparative assessment of three AI platforms in answering USMLE Step 1 anatomy questions or identifying anatomical structures on radiographs.

The application of artificial intelligence (AI) in education has gained great attention recently. Integration of AI tools in anatomy teaching is currently engaging researchers and academics worldwide. Several AI chatbots have been generated, the most popular being ChatGPT (OpenAI: San Francisco, California, USA).

Minimizing Blood Loss Using Tranexamic Acid in Patients Undergoing Liposuction: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Background: Liposuction has become the most sought-after aesthetic surgery across the globe, increasing the demand for more developments in patient safety protocols. Evidence of the efficacy of tranexamic acid (TXA) in reducing intraoperative blood loss with minimal complications have led to its widespread applications across various surgical operations. However, the role and effectiveness of TXA in liposuction is not fully understood.