3,871 results match your criteria: "Imaging in Tetralogy of Fallot"

Background: Biventricular dysfunction is frequent in patients with repaired tetralogy of Fallot, necessitating routine imaging to monitor for worsening conditions and determine whether procedures like pulmonary valve replacement (PVR) are needed. This study aimed to highlight the parameters of cardiac magnetic resonance imaging (CMR) and their association with adverse outcomes in the midterm follow-up of these patients.

Methods: This longitudinal study recruited all patients with a history of tetralogy of Fallot total correction (TFTC) who had two CMR images at a minimum three-month interval at Rajaie Center from 2007 through 2017.

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Post-operative transesophageal echocardiography (TEE) is standard of care to evaluate for residual disease and quality of surgical repair. The residual lesion score (RLS) as defined by the pediatric heart network explored the impact of residual lesions on outcomes using discharge transthoracic echocardiogram (TTE). In tetralogy of fallot with pulmonary stenosis (TOF/PS), the residual right ventricular outflow tract (RVOT) gradient is one marker of quality of repair.

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Purpose: Pulmonary valve replacement (PVR) using bioprosthetic valves is a common procedure performed in patients with repaired Tetralogy of Fallot and other conditions, but these valves frequently become dysfunctional within 15 years of implantation. The causes for early valve failure are not clearly understood. The purpose of this study was to explore the impact of changing cardiac output (CO) and valve orientation on local hemodynamics and valve performance.

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Article Synopsis
  • - The study assesses the effectiveness of fetal MRI in diagnosing total anomalous pulmonary venous connection (TAPVC) and its impact on fetal brain development by comparing brain volumes in affected fetuses to normal controls and those with another heart condition, tetralogy of Fallot (TOF).
  • - Among 21 TAPVC fetuses studied, the majority were classified as supracardiac or intracardiac, with significant post-natal confirmation of cases, while some fetuses also presented other cardiac abnormalities.
  • - Key MRI findings included a dilated coronary sinus and pulmonary edema, with notable differences in brain volumes where TAPVC fetuses exhibited lower cerebellum and brainstem volumes compared to controls, alongside an increase in subc
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Myocardial strain analysis by cardiac magnetic resonance associated with arrhythmias in repaired tetralogy of Fallot patients.

BMC Med Imaging

December 2024

Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.

Article Synopsis
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[Patch Closure of the Ventricular Septal Defect].

Kyobu Geka

September 2024

Department of Pediatric Cardiovascular Surgery, JCHO Kyushu Hospital, Kitakyushu, Japan.

Article Synopsis
  • Ventricular septal defect (VSD) is the most common type of congenital heart disease and often requires surgical intervention.
  • The VSD patch closure surgery is crucial not only for simple VSDs but also for more complex congenital heart defects like tetralogy of Fallot and complete atrioventricular septal defect.
  • To ensure successful closure without complications, surgeons must have a thorough understanding of VSD anatomy and skillfully perform sutures and ligatures.
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  • Cognitive impairment is a common issue in children with congenital heart disease (CHD), particularly in those with Tetralogy of Fallot (TOF), and this study explores how TOF affects brain network organization.
  • The research involved 29 preschool-aged children with TOF and 19 without CHD, utilizing diffusion tensor imaging to analyze brain structures, revealing significant differences in network properties between the two groups.
  • Key findings indicate that TOF children showed impaired brain connectivity and efficiency, which correlated with poorer cognitive performance, suggesting that disruptions in brain network integration could underlie cognitive deficits in these children.
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Article Synopsis
  • Right ventricular outflow dysfunction is a common issue in patients with repaired tetralogy of Fallot, leading to increased health risks as they age.
  • The American Heart Association has released an update focusing on how to monitor and treat this condition effectively, including new therapies and techniques for managing complications.
  • The statement highlights the importance of understanding how other health issues and patients' perspectives affect their quality of life and includes discussions on when and how to perform pulmonary valve replacements.
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  • * Conducted with 129 patients at a cardiology center in Karachi, results showed that 70.5% experienced a delay in diagnosis, with the mean diagnosis age being 12.4 years.
  • * The primary reason for delays was found to be delayed referral from other healthcare providers, and the most prevalent type of CHD was ventricular septal defect.
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  • Patent ductus arteriosus (PDA) stent placement is a common procedure for children with certain heart conditions.
  • A rare complication occurred during a stenting procedure in a newborn with Tetralogy of Fallot and pulmonary atresia, where tissue protrusion reduced the stent's lumen size.
  • The issue was resolved by inserting a shorter stent within the original one at the site of the tissue protrusion.
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A 14-year-old child with recurrent cyanotic spells at the age of 9 months underwent echocardiography at that time, which revealed tetralogy of Fallot (TOF). Follow-up computed tomography angiography revealed TOF with valvular pulmonary stenosis and a right-sided aortic arch with mirror image branching. Interestingly, an unusual anomalous course of the left brachiocephalic vein was seen.

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Clinical outcomes of right ventricular outflow tract stenting compared to surgical shunting in late-presenting children.

Front Cardiovasc Med

October 2024

Division of Non-Invasive Diagnostic and Cardiovacular Imaging, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Universitas Indonesia, Jakarta, Indonesia.

Article Synopsis
  • The study examined the use of right ventricular outflow tract (RVOT) stenting versus the modified Blalock-Taussig shunt (mBTS) as treatments for children with stenotic RVOTs aged 1 to 18, revealing limited literature on their comparative effectiveness.* -
  • Data from 58 patients indicated that both procedures resulted in similar rates of major adverse cardiovascular events (MACE), but mBTS patients had shorter overall hospital stays, while RVOT stenting led to shorter ICU stays.* -
  • Overall, RVOT stenting showed comparable results to mBTS concerning MACE and oxygen saturation levels at discharge, suggesting it could be a viable option for palliation in this patient population.*
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Article Synopsis
  • The study investigates the effectiveness of intracardiac echocardiography (ICE) in improving catheter ablation outcomes for ventricular tachycardia (VT) in adults with repaired tetralogy of Fallot (TOF).
  • Results showed that ICE significantly enhanced isthmus localization and ablation success rates, but did not improve long-term freedom from VT or affect overall procedural times and complications.
  • The conclusion emphasizes that while ICE is beneficial for tailored ablation based on individual anatomy, it does not lead to better long-term patient outcomes for VT in the context of repaired TOF.
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Assessment of the right ventricular outflow tract and pulmonary arteries (RVOT) for percutaneous pulmonary valve implantation (PPVI) uses discrete measurements (diameters and lengths) from medical images. This multi-centre study identified the 3D RVOT shape features prevalent in patients late after surgical repair of congenital heart disease (CHD). A 3D RVOT statistical shape model (SSM) was computed from 81 retrospectively selected CHD patients (14.

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Non-invasive pressure-volume loops show high arterial elastance in children with repaired tetralogy of Fallot.

Scand Cardiovasc J

December 2024

Clinical Physiology, Department of Clinical Sciences Lund, Skåne University Hospital, Lund University, Lund, Sweden.

Article Synopsis
  • Children with repaired tetralogy of Fallot (rToF) exhibit distinct changes in left ventricular (LV) function and right ventricular (RV) size compared to healthy peers, including larger RV volumes and smaller LV volumes.
  • The study measured haemodynamic variables using non-invasive techniques, revealing higher arterial elastance and heart rates in children with rToF, suggesting a compensatory response to impaired LV filling.
  • Further research is needed to understand the implications for cardiovascular health and the potential increased risk for adverse events in these patients.
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Article Synopsis
  • - The study investigates neurodevelopmental issues in preschool children with tetralogy of Fallot (TOF) and aims to identify objective imaging markers using advanced MRI techniques, focusing on radiomics and morphological features.
  • - It involved 33 children who had surgery for TOF and 29 healthy controls, utilizing high-resolution MRI to extract features for constructing predictive models and implementing machine learning methods for analysis.
  • - The effectiveness of the imaging markers was evaluated against clinical neurodevelopmental assessments, exploring correlations between the imaging findings and cognitive development metrics.
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Article Synopsis
  • The study seeks to improve risk stratification for patients with congenital heart disease (CHD) by using an AI-enhanced electrocardiogram (ECG) tool, addressing a significant gap in current medical practice.* -
  • A convolutional neural network was developed and tested on a large set of ECGs from patients at Boston Children's Hospital to predict 5-year mortality, showing good performance compared to traditional indicators like age and heart function metrics.* -
  • The model displays potential for timely risk assessment across various ages and types of CHD, helping to guide future monitoring and therapeutic interventions for patients.*
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Article Synopsis
  • Tetralogy of Fallot patients often develop complications like chylothorax and pleural effusions after surgery due to factors affecting their lymphatic system.
  • This study evaluated the structure and function of the lymphatic system in young post-repair patients using advanced imaging techniques.
  • Although no clinical lymphatic disease was observed, some patients showed significant lymphatic abnormalities, prompting the need for further research to understand the cause and implications of these findings.
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Article Synopsis
  • Tetralogy of Fallot with an absent pulmonary valve is a rare heart problem where some important parts of the heart are not properly formed, leading to serious issues.
  • The study looked at 300 patients over ten years, finding 18 who had this specific issue, and they learned how it affects them and how doctors manage it.
  • Most patients were diagnosed very young, and while surgery helped many, they still had some health problems afterwards, but no one died from the surgery.
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Article Synopsis
  • Fetal two-dimensional speckle tracking echocardiography (2D-STE) assesses fetal heart function by measuring global longitudinal strain (GLS) and strain rate (GLSR), which indicate how the heart walls stretch and deform.
  • The systematic review found that fetuses with congenital heart diseases (CHD) like coarctation of the aorta and Tetralogy of Fallot have significantly lower LV-GLS, while those with a single left ventricle show higher LV-GLS values.
  • The study highlights the need for more longitudinal research on 2D-STE in fetuses with CHD to better interpret the findings and explore its potential in predicting outcomes, given the observed variability across different
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Article Synopsis
  • This study reviews surgical outcomes of pulmonary valve replacements in adults with congenital heart disease, specifically focusing on patients who underwent this procedure over the past decade.
  • A total of 79 patients were analyzed, with the majority having Tetralogy of Fallot, and the surgery involved removing the old valve and using a larger bioprosthesis, often alongside other surgeries like tricuspid valve repairs.
  • Results showed effective post-operative outcomes, with no severe valve insufficiency noted and improved heart function metrics in MRI studies, confirming sPVR as a safe and effective treatment option with a low mortality rate (5.1%).
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Investigation of the Clinical Value of Four Visualization Modalities for Congenital Heart Disease.

J Cardiovasc Dev Dis

September 2024

Discipline of Medical Radiation Science, Curtin Medical School, Curtin University, Perth, WA 6845, Australia.

Article Synopsis
  • Diagnosing congenital heart disease (CHD) is tough due to its complex structures and variability, making conventional 2D visualizations inadequate.
  • This study explored the effectiveness of four different visualization tools: DICOM images, 3D-printed heart models (3DPHM), virtual reality (VR), and 3D PDFs, using three CHD cases.
  • Results showed that 76.4% of specialists preferred VR for understanding spatial relationships in the heart and presurgical planning, while 94.1% favored 3DPHM for patient communication and education, highlighting the strengths of both advanced technologies.
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