408 results match your criteria: "Imaging in Pineal Germinoma"
Massive intratumoral hemorrhage following ventriculoperitoneal shunting procedure in an 8-year-old boy: A case report.
Surg Neurol Int
November 2024
Department of Neurosurgery, Dr. Soetomo General Hospital/Faculty of Medicine, Airlangga University, Surabaya, East Java, Indonesia.
Background: Pineal region tumors comprise 0.4% of all central nervous system tumors in adults and 2.8% in children aged up to 19 years.
View Article and Find Full Text PDFSeminoma characterized by thickening of the pituitary stalk A case report.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
June 2024
Department of Endocrinology, First Affiliated Hospital of Army Medical University, Chongqing 400038.
Article Synopsis
- Intracranial seminoma is a rare type of cancer that starts in special cells in the brain, often found in the pineal or pituitary gland.
- A 20-year-old patient had headaches and vision problems and was diagnosed with this cancer after an MRI showed issues with his pituitary stalk.
- He had surgery to remove the tumor and received treatment, but it came back a year later, leading to another surgery and ongoing treatments, although he still faces some health challenges.
Consensus guidelines for the management of pineal region tumours for low- and middle-income countries.
J Pak Med Assoc
March 2024
Department of Neurosurgery, The Aga Khan University, Karachi, Pakistan.
Article Synopsis
- * These tumors often cause obstructive hydrocephalus and symptoms such as headaches, nausea, and impaired gait due to mass effect.
- * Diagnosis primarily relies on imaging, while biopsy is required for histologic confirmation, except for germinomas, which can be identified through specific tumor markers; treatments vary from surgery for benign tumors to additional chemotherapy and radiotherapy for malignant ones.
Suprasellar teratoma to germinoma recurrence: implications for diagnosis and follow-up.
Childs Nerv Syst
December 2024
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Article Synopsis
- A mature teratoma is a type of brain tumor that is usually not harmful and has a good chance of recovery after surgery.
- In this case, a 7-year-old girl had a tumor removed and was thought to be okay, but six months later, a new tumor called a germinoma showed up nearby.
- After the second surgery, the girl got special treatment including chemotherapy and proton therapy, and she got all better, showing that careful follow-up is really important for patients with this type of tumor.
A Unique Case of Intracranial Bifocal Germinoma.
Cureus
June 2024
Neurological Surgery, Nizam's Institute of Medical Sciences, Hyderabad, IND.
Primary intracranial germ cell tumors are rare tumors that often occur in children and young adults. We report a case of a 17-year-old male, who presented with vomiting, headache, and blurring of vision of the left eye on the temporal aspect for two months. His biological assessment showed panhypopituitarism.
View Article and Find Full Text PDFPituitary germinoma after resection of a mature third ventricular teratoma: illustrative case.
J Neurosurg Case Lessons
July 2024
Department of Neurosurgery, University Hospital Basel, Basel, Switzerland.
Article Synopsis
- A 9-year-old boy had balance problems, headaches, and other symptoms, leading to MRI scans that found a brain tumor called a teratoma.
- After surgery to remove the teratoma, he recovered well but later developed another tumor called a germinoma 3.5 years later.
- Doctors emphasize the importance of regular check-ups for patients who have had brain tumors, even if they seem healthy, because new tumors can appear later.
The role of neurosurgeon in the multidisciplinary approach to ectopic or bifocal intracranial germinoma: A systematic review and report of two illustrative cases.
Clin Neurol Neurosurg
September 2024
Division of Neurosurgery, Department of Basic Medical Sciences, Neurosciences and Sense Organs, University "Aldo Moro" of Bari, Bari, Italy.
Article Synopsis
- Pure germinoma is a rare brain tumor that usually starts in the middle of the brain; sometimes it can be found in two places at once or outside the usual spots, which is very uncommon.
- Researchers reviewed many studies to look at how doctors diagnose and treat patients with these rare brain tumors and to find ways to help them faster.
- The review showed that most patients needed a biopsy (taking a small sample for testing), and many had these tumors in unusual places, which can make it hard to find and treat them quickly.
Clinical effects of neuroendoscopic infratentorial supracerebellar approach surgical technique for resecting pineal tumors: a retrospective study.
Neurochirurgie
September 2024
Department of Neurosurgery, Second Hospital of Lanzhou University, Lanzhou 730030, China. Electronic address:
Article Synopsis
- Pineal tumors are rare brain growths, mostly found in kids, and this article studies a special surgical method to remove them.
- The study looked at nine patients who had surgery using a technique called neuroendoscopy to take out tumors from the pineal area between 2017 and 2023.
- After the surgeries, all patients were okay, with no tumors coming back, although some had minor vision and walking problems; but they all lived normal lives after a few years.
Radiological Insights From Two Distinct Cases of Pineal Region Meningioma: A Case Report.
Cureus
April 2024
Radiodiagnosis, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University, Chennai, IND.
Article Synopsis
A case of a pineal parenchymal tumor of intermediate differentiation with bifocal lesions differentiated by negative placental alkaline phosphatase in the spinal fluid.
Childs Nerv Syst
September 2024
Department of Neurosurgery, Tokyo Women's Medical University, 8-1 Kawada-cho Shinjuku-ku, Tokyo, 162-8666, Japan.
Article Synopsis
- Scientists found that checking for a special protein called PLAP in the spinal fluid helps doctors figure out if a patient has a specific type of brain tumor called a germinoma.
- They looked at a 15-year-old boy who had tumors in two places in his brain, but tests showed he didn’t have that protein, making them think it might be a different kind of tumor.
- After doing some surgery to remove the tumors, they discovered it was a less common type called a pineal parenchymal tumor, teaching doctors that PLAP can help tell different tumors apart for better treatment.
A Case of Multifocal Ectopic Germinoma Manifesting with Medial Longitudinal Fasciculus Syndrome.
Case Rep Oncol
March 2024
Department of Neurosurgery, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Article Synopsis
Neoadjuvant Chemotherapy Approach to Pineal Germinoma: A Case Report.
Cureus
January 2024
Medicine, American University of Beirut Medical Center, Beirut, LBN.
Article Synopsis
- Intracranial germ cell tumors (GCTs) are rare, harmful tumors that usually show up around puberty, especially in the pineal region of the brain.
- A 20-year-old boy had a pineal germinoma, which caused him to vomit and feel less conscious; doctors used MRI scans to find the tumor and placed a special device to relieve pressure in his brain.
- There isn't a clear way to treat these tumors yet, so more studies are needed to find the best treatment methods.
Bilateral uveitis, retinal periphlebitis, and optic neuritis associated with non-pineal central nervous system germinoma.
Retin Cases Brief Rep
December 2023
Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA.
Article Synopsis
- - A 32-year-old male experienced severe visual issues, leading to the diagnosis of bilateral uveitis, retinal periphlebitis, and optic neuritis caused by a non-pineal central nervous system (CNS) germinoma.
- - Upon examination, he showed several eye problems, including decreased visual acuity, optic disc edema, and abnormal imaging findings, which led to further investigation and a brain biopsy confirming the germinoma.
- - Treatment with chemotherapy for the germinoma resulted in significant improvement of his ocular symptoms, highlighting the connection between CNS germinomas and eye conditions like optic neuritis and uveitis.
A Pineal Germinoma with Rapid Enlargement following Tumor Resection.
Diagnostics (Basel)
December 2023
Department of Neurosurgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
The natural course of pineal germ cell tumors (GCTs), particularly their post-operative progression, is not well understood. We report a rare case of pineal region GCT showing rapid enlargement within 2 weeks following surgical resection. A young adult male presented with progressive headache and diplopia for several weeks.
View Article and Find Full Text PDFA Case of Central Diabetes Insipidus in a Patient With a Pineal Mass Suspected to Be a Germinoma: A Case Report.
Cureus
September 2023
Internal Medicine, Appalachian Regional Healthcare, Harlan, USA.
Article Synopsis
- * In young people, tumors are a common cause of CDI, and one type of tumor called germinoma is the most frequent.
- * A 22-year-old man with a condition called infundibuloneurohypophysitis was treated, but later doctors found a new mass in his brain that might be a germinoma, showing that it's really important to keep checking on people with unknown causes of CDI.
Unraveling the impact of upfront chemotherapy and proton beam therapy on treatment outcome and follow-up in central nervous system germ cell tumors: a single center experience.
Front Oncol
October 2023
Department of Pediatric Haematology and Oncology, and Cell and Gene Therapy Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Article Synopsis
- Germ cell tumors (GCT) are a type of brain cancer that mostly affects teenagers and young adults, but they can often be treated successfully with chemotherapy and radiation therapy.
- A study looked at 17 patients treated for these tumors, and most of them had good results, with only one person having a relapse.
- Proton beam radiation (PBT) was shown to be a safe and effective treatment, helping to keep patients' brains working well without causing serious side effects.
[Molecular Characteristics and Clinical Significance of Germ Cell Tumors].
No Shinkei Geka
September 2023
Department of Neurosurgery, The University of Tokyo Hospital.
Article Synopsis
- * Doctors diagnose these tumors using imaging tests, looking for tumor markers in the blood, and studying tissue samples. Treatment plans change based on whether the tumor type is germinoma or non-germinoma, with surgery being an option for certain cases.
- * New research is helping scientists understand the genes involved in these tumors, which may lead to better, more targeted treatments for young patients in the future.
A 2-step prediction model for diagnosis of germinomas in the pineal region.
Neurooncol Adv
August 2023
Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Article Synopsis
- Germinomas are a type of tumor in the brain that respond well to treatments like radiation and chemotherapy, and this study focuses on finding a better way to diagnose them.
- Researchers looked at 126 patients with different types of pineal region tumors to create a two-part model that helps tell germinomas apart from other tumors using clinical information and MRI scans.
- The models they developed were very accurate at predicting the types of tumors, making it easier for doctors to decide on treatments without needing to do invasive procedures.
Occult extracranial malignancy after complete remission of pineal mixed germ cell tumors: a rare case report and literature review.
BMC Pediatr
September 2023
Department of Neurosurgery, Institute of Brain Disease, Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong, 510515, China.
Article Synopsis
- A 12-year-old boy with a brain tumor showed symptoms like dizziness and headaches, and doctors found a type of cancer called a germ cell tumor (GCT) in his brain that was removed successfully.
- After treatment, he was doing well, but eight months later, he came back to the hospital with stomach pain and found to have cancer spreading to other parts of his body.
- Despite more treatments, his condition got worse quickly, and he unfortunately passed away, highlighting how hard it is to catch hidden cancer spread from brain tumors early enough.
Depression and Nystagmus as the Rare Masquerading Presentations of Pineal Germinoma.
Cureus
July 2023
Department of Ophthalmology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.
Convergence-retraction nystagmus alongside behavioral changes can be rare manifestations of a potentially life-threatening midbrain lesion. After experiencing headaches for three months, a 13-year-old boy was diagnosed with depression due to exhibiting reduced speech, hypersomnia, and psychomotor slowing for three weeks. It was preceded by headache for three months.
View Article and Find Full Text PDFMachine learning-based classification of pineal germinoma from magnetic resonance imaging.
World Neurosurg X
October 2023
Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Article Synopsis
- This study looked at using machine learning (ML) to help doctors figure out what kind of tumors are in the pineal area of the brain.
- The researchers tested different ways to analyze MRI images from patients and found that one method, using the K-nearest neighbors (KNN) algorithm, worked best for identifying tumors.
- The study suggests that using ML can help doctors make better treatment plans for patients with pineal tumors in the future.
Brain and Spinal Tumors Originating from the Germ Line Cells.
Adv Exp Med Biol
July 2023
Department of Physical Medicine and Rehabilitation, Taipei Veterans General Hospital, Taipei, Taiwan.
Article Synopsis
- Primary central nervous system germ cell tumors (CNS GCTs) happen in both kids and adults, often appearing in early life and during teenage years.
- There are different types of these tumors, like germinomas and nongerminomatous GCTs, which can develop in areas like the brain's pineal region and cause issues like hydrocephalus (fluid buildup).
- Treatment usually involves a mix of surgery, chemotherapy, and sometimes radiation, depending on the tumor type and its location.
Primary Intracranial Germ Cell Tumors: A Study with an Integrated Clinicopathological Approach.
Neurol India
June 2023
Department of Pathology, Tata Memorial Hospital and ACTREC, Tata Memorial Center, Homi Bhabha National Institute (HBNI), Mumbai, Maharashtra, India.
Background And Objective: Primary intracranial germ cell tumors (ICGCTs) are rare and are histologically classified as germinomas and non-germinomatous with distinctive prognostic and therapeutic implications. ICGCTs, essentially due to the inherent difficulty of surgical access, pose different challenges and management connotations than their extracranial counterparts. This is a retrospective analysis of histologically verified ICGCTs, which was undertaken to evaluate various clinicopathological features and their implications on patient management.
View Article and Find Full Text PDFDiagnosis and Management of Pineal Germinoma: From Eye to Brain.
Eye Brain
April 2023
Department of Neurosurgery, University of Missouri School of Medicine, Columbia, MO, USA.
Article Synopsis
- Pineal germinomas are tricky tumors found in the brain that can cause various symptoms and are hard to diagnose.
- Doctors use eye tests and signs of increased pressure in the brain to figure out if someone has this tumor, and special scans and tests are needed for more information.
- Surgery might be done just to confirm the diagnosis, but treatments like chemotherapy and radiation work well, and most people do really well after treatment, even though some may have to deal with it coming back later.
Outcome of Children and Adolescents With Primary Intracranial Germinoma Treated With Chemotherapy and Reduced Dose-Field Irradiation: A Prospective Brazilian Experience.
JCO Glob Oncol
April 2023
Paediatric Oncology, The Ohio State University, Columbus, OH.