[Therapeutic and diagnostic classification of degenerative spondylolisthesis: validation and multiple-center inter-observer agreement].

Object: To evaluate inter- and intra-observer agreement of the proposed diagnostic and treatment classification of degenerative spondylolisthesis.

Material And Methods: The proposed diagnostic and treatment classification of degenerative spondylolisthesis was validated according to the GRRAS protocol. For this purpose, we retrospectively analyzed MRI, CT and spinal radiography data in 20 patients.

Long Bone Defect Filling with Bioactive Degradable 3D-Implant: Experimental Study.

Previously, 3D-printed bone grafts made of titanium alloy with bioactive coating has shown great potential for the restoration of bone defects. Implanted into a medullary canal titanium graft with cellular structure demonstrated stimulation of the reparative osteogenesis and successful osseointegration of the graft into a single bone-implant block. The purpose of this study was to investigate osseointegration of a 3D-printed degradable polymeric implant with cellular structure as preclinical testing of a new technique for bone defect restoration.

Types of Vascular Response to Direct Intraoperative Electrical Stimulation of the Sciatic Nerve after Autoneuroplasty and Their Effect on Limb Function Recovery.

We studied different types of the vascular response to direct intraoperative low-frequency electrical stimulation of the sciatic nerve after autoneuroplasty of its tibial portion and analyzed their effects on the limb function recovery. Rats (n=20) underwent 40-min intraoperative electrical stimulation, and hemodynamics in the leg was recorded by photoplethysmography. Functional recovery of the tibial nerve was assessed using a walking path analysis within 12 weeks after surgery.

Hydrolysis of Bone-Replacing Materials Based on Polylactic Acid and Containing Hydroxyapatite in an In Vitro Experiment.

We studied the features of hydrolytic degradation of polylactic acid (PLLA) implants depending on their structural filling with hydroxyapatite (HA). The resistance to in vitro hydrolysis was tested for the following samples: PLLA without HA (control; group 1), PLLA/HA 25 wt% (group 2), and PLLA/HA 50 wt% (group 3). Samples were incubated at 37°C.

Prediction Criteria for the Formation of Refracture after Union of a Long Bone Fracture on the Basis of Hemodynamic Changes in the Tissues of the Area of Damage.

We studied hemodynamic changes in the area of leg bone fracture and determined the prognostic criteria for refracture formation after achieved union. In Wistar rats (n=18), shin bone fracture with external fixation of the fragments was modeled. The union was formed 35 days after osteosynthesis, the device was removed at this term.

International recognition of the Ilizarov bone reconstruction techniques: Current practice and research (dedicated to 100 birthday of G. A. Ilizarov).

The Ilizarov method is one of the current methods used in bone reconstruction. It originated in the middle of the past century and comprises a number of bone reconstruction techniques executed with a ring external fixator developed by Ilizarov GA. Its main merits are viable new bone formation through distraction osteogenesis, high union rates and functional use of the limb throughout the course of treatment.

Osteointegration technology in long bone defect reconstruction: experimental study.

Purpose: The purpose of this experimental study was to evaluate the osteointegration of a bioactive 3D-cylindrical titanium-alloy implant (bone-graft substitute) for tibial shaft defect reconstruction.

Methods: An experimental study was done in 7 mongrel dogs. Tibial shaft defect was repaired using an original titanium-alloy (Ti6Al4V) cellular cylindrical implant.