6,428 results match your criteria: "Idiopathic Intracranial Hypertension"
Identifying idiopathic intracranial hypertension in a hospital-based chronic headache population: Utility of magnetic resonance imaging, magnetic resonance venography and trans-orbital sonography.
Cephalalgia
October 2024
Department of Neurology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Article Synopsis
- Chronic headaches can often stem from cerebro-spinal fluid issues, with Idiopathic Intracranial Hypertension (IIH) being a key example that presents with headaches and vision problems along with signs like papilledema.
- In a study of 168 headache patients, 141 were evaluated, revealing that 27% had IIH, typically characterized by specific headache types, age, and body mass index.
- Diagnostic methods such as fundus examination and MRI/MR venography prove effective in detecting IIH, even identifying cases lacking typical signs like papilledema.
The pivotal role of neurosurgeons in transitional care: A comprehensive tertiary healthcare institution's experience.
Childs Nerv Syst
December 2024
Division of Neurosurgery, Department of Surgery, National University Hospital, Singapore, Singapore.
Article Synopsis
- Transitional care (TC) is vital in neurosurgery, especially for managing the complex transition of patients from pediatric to adult care, which is often complicated by different attending neurosurgeons and institutions.
- A study reviewed clinic visit data from 2019-2023, focusing on patients aged 16 to 26, to understand successful transitions, defining success as continued follow-up without losing patients.
- Results showed that of 1,829 patients, 78 required adult follow-up, all of whom successfully transitioned, with the key factor being the continuity of care from the same providers and the integration of pediatric and adult neurosurgery within the same institution.
Clinical outcomes of bariatric surgery in patients with obesity and idiopathic intracranial hypertension.
Surg Endosc
October 2024
Department of General Surgery, Cleveland Clinic, Bariatric and Metabolic Institute, Cleveland, OH, USA.
Article Synopsis
- Obesity significantly increases the risk of idiopathic intracranial hypertension (IIH), and this study investigates how bariatric surgery impacts clinical outcomes for patients with both conditions.
- The study analyzed data from 97 predominantly female patients (median age 46.7) who underwent various types of bariatric surgery, leading to a median weight loss of 24% and notable improvements in IIH symptoms, including headaches and visual issues.
- Results showed a significant reduction in mean lumbar opening pressure and a decrease in the usage of medications for IIH post-surgery, indicating that bariatric surgery can effectively alleviate IIH symptoms in obese patients.
Jugular venous narrowing and spontaneous spinal cerebrospinal fluid leaks: A case-control study exploring association and proposed mechanism.
Interv Neuroradiol
December 2024
Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Hospital, Baltimore, MD, USA.
Article Synopsis
The correlation between intracranial pressure and venous sinus pressures changes after venous sinus stenting.
J Neurointerv Surg
October 2024
Neurological Surgery and Radiology, Atrium Wake Forest Baptist Health, Winston-Salem, North Carolina, USA.
Background: The pathophysiology of idiopathic intracranial hypertension (IIH) and other cerebral venous outflow disorders (CVD) has largely been unexplored. While a correlation between venous sinus pressure and opening pressure (OP) has been previously noted, there are limited data on this relationship in patients with prior venous sinus stenting (VSS).
Methods: A single center retrospective chart review was conducted on CVD patients who underwent diagnostic cerebral venography with manometry followed immediately by lateral decubitus lumbar puncture, from 2016 to 2024.
Therapeutic Cerebral Fluid Puncture in Patients with Idiopathic Intracranial Hypertension: No Short-Term Effect on Neurocognitive Function.
Brain Sci
August 2024
Department of Neurology, LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Background: Idiopathic intracranial hypertension (IIH) is typically characterized by headaches and vision loss. However, neurocognitive deficits are also described. Our study aimed to test the influence of therapeutic lumbar puncture on the latter.
View Article and Find Full Text PDFA management algorithm for idiopathic intracranial hypertension in skull base meningoencephaloceles.
J Neurosurg
September 2024
1Cleveland Clinic Lerner College of Medicine, Case Western Reserve University School of Medicine, Cleveland.
Article Synopsis
- The study evaluated an algorithm designed for diagnosing and managing idiopathic intracranial hypertension (IIH) in patients who had surgery for skull base meningoencephaloceles and experienced spontaneous cerebrospinal fluid (sCSF) leaks.
- The researchers reviewed records from 80 patients treated between 2014 and 2021, measuring their opening pressure (OP) and categorizing them into high, intermediate, or low-risk groups based on the OP.
- The findings revealed a VPS rate of 15%, with low recurrence rates for acute (3.8%) and remote CSF leaks (3.8%), highlighting the effectiveness of the proposed management strategy in understanding CSF dynamics in these patients.*
Multi- and poly-pharmacology of carbonic anhydrase inhibitors.
Pharmacol Rev
September 2024
Neurofarba Department, University of Firenze, Italy
Eight genetically distinct families of the enzyme carbonic anhydrase (CA, EC 4.2.1.
View Article and Find Full Text PDFMacular exudate in idiopathic intracranial hypertension affects outer retina and visual acuity.
BMJ Open Ophthalmol
September 2024
Department of Neurology, West China Hospital, Sichuan University, Chengdu, China
Article Synopsis
- Optical coherence tomography (OCT) is being studied for its potential to identify retinal changes in patients with idiopathic intracranial hypertension (IIH), particularly focusing on macular exudate (ME) and its impact on retinal structure.
- A study involving 98 IIH patients and 112 controls revealed that IIH patients generally had thicker inner retinal layers, with those having ME showing even greater thickness.
- The findings suggest that ME in IIH patients is linked to higher intracranial pressure, worse vision, and more severe ocular symptoms, indicating that OCT could be useful for monitoring clinical changes in IIH.
Neuroborreliosis with intracranial hypertension and visual loss in a pediatric patient: illustrative case.
J Neurosurg Case Lessons
September 2024
Department of Neurosurgery, Albany Medical Center, Albany, New York.
Background: Approximately 15% of Lyme disease cases involve the nervous system and are termed "neuroborreliosis." A rare complication of neuroborreliosis is idiopathic intracranial hypertension with resulting neurological deterioration. There are very few reports of this in the literature, most of which consist of case reports and small case series.
View Article and Find Full Text PDFVenous sinus stenosis intracranial hypertension, rethinking idiopathic intracranial hypertension in the setting of venous sinus stenosis: A call for new nomenclature and diagnostic precision.
Interv Neuroradiol
September 2024
Department of Neurosurgery, University of Illinois Chicago, Chicago, IL, USA.
Idiopathic intracranial hypertension (IIH) is traditionally characterized by elevated intracranial pressure without an identifiable cause, primarily affecting obese women. However, recent evidence suggests that venous sinus stenosis may play a significant role in the pathophysiology of IIH, challenging its designation as "idiopathic." This editorial discusses the limitations of the current nomenclatures and diagnostic criteria, highlighting the importance of routine venography in detecting venous sinus abnormalities, irrespective of a patient's demographic profile.
View Article and Find Full Text PDFComplete Third Nerve Palsy: A Rare Occurrence in Fulminant IIH Case Report.
Neurohospitalist
October 2024
Department of Neurology SUNY - Upstate Medical University Hospital, Syracuse, NY, USA.
Article Synopsis
- Idiopathic Intracranial Hypertension (IIH) involves increased intracranial pressure with unknown origins, leading to symptoms like headaches, vision problems, and sometimes unusual presentations.
- Typical symptoms include headaches, visual disturbances, and diplopia, but atypical signs may involve nerve palsies and other sensory issues.
- The report highlights a rare case of fulminant IIH, marked by a sudden decline in vision accompanied by unilateral complete third nerve palsy.
Etiology and characteristics of non-aneurysmal thunderclap headache presenting to an acute setting.
Am J Emerg Med
November 2024
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Objectives: To describe the characteristics and causes of non-aneurysmal thunderclap headache (TCH) and compare serious from benign underlying causes.
Methods: Retrospective cohort study of consecutive adult patients with TCH presenting to a tertiary care academic medical center between 2010 and 2020. Aneurysmal subarachnoid hemorrhage cases were excluded.
Geniculate ganglion diverticulum: a potential imaging marker in patients with idiopathic intracranial hypertension.
Clin Imaging
November 2024
Division of Otolaryngology-Head and Neck Surgery, George Washington University School of Medicine & Health Sciences, 2300 M St NW 4th floor, Washington, DC 20037, United States of America. Electronic address:
Purpose: The diagnosis of idiopathic intracranial hypertension (IIH) is often challenging in patients who do not present with classic symptoms. Brain MRI can play a pivotal role, as several imaging findings, such as an empty sella appearance (ESA), have been shown to be associated with IIH. Yet, none of the MRI signs have been shown to have a high sensitivity and specificity.
View Article and Find Full Text PDFConcordance between venous sinus pressure and intracranial pressure in patients investigated for idiopathic intracranial hypertension.
J Headache Pain
September 2024
Neuroradiology department, Montpellier University Hospital, Gui De Chauliac, 80 Avenue Augustin Fliche, Montpellier, 34000, France.
Article Synopsis
- Idiopathic intracranial hypertension (IIH) is linked to chronic headaches driven by high intracranial pressure (ICP) and potentially influenced by cerebral venous sinus pressure, which needs more research to understand their relationship.
- A study investigated 52 patients suspected of having IIH, measuring both lumbar puncture opening pressure (LPOP) and cerebral venous sinus pressure, finding strong correlations between these measurements.
- Results confirmed that the torcular pressure aligns closely with LPOP, indicating that these two methods are consistent for assessing ICP in IIH patients, which can help in clinical decision-making.
Safety profile of levonorgestrel intrauterine system: Analysis of spontaneous reports submitted to FAERS.
Heliyon
September 2024
Department of Pharmacy, Women and Children's Hospital of Chongqing Medical University, CHONGQING, 400021, China.
Article Synopsis
- The levonorgestrel-releasing intrauterine system (LNG-IUS) is a popular long-term birth control method, but its usage has raised concerns about potential adverse events (AEs).
- A real-world analysis was conducted using the FDA's Adverse Event Reporting System (FAERS) database to investigate the incidence of AEs related to LNG-IUS from 2004 to 2024, focusing on specific reporting methods to identify significant safety signals.
- Key findings highlighted new potential AEs associated with LNG-IUS, such as increased heart rate and pelvic complications, emphasizing the need for further long-term studies to confirm these safety concerns.
Are Peripapillary Hyperreflective Ovoid Mass-like Structures with an Elevated Optic Disc Still a Diagnosis Dilemma?
Ophthalmology
September 2024
Department of Neuro-Ophthalmology, Rothschild Foundation Hospital, Paris, France.
Purpose: To identify clinical characteristics that would help make or rule out the diagnosis of idiopathic intracranial hypertension (IIH) in patients referred for papilledema (PE) with peripapillary hyperreflective ovoid mass-like structures (PHOMS).
Design: A retrospective cohort study.
Participants: All patients referred for PE excluding PE with Frisén grade ≥ 3, optic neuritis, ischemic optic neuropathy, and compressive optic neuropathy.
A Case Report of Verheij Syndrome.
Cureus
August 2024
Pediatric Endocrinology, G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, IND.
Verheij syndrome (VRJS) is a rare genetic disorder characterized by a range of developmental issues and physical abnormalities. This condition is caused by mutations or deletions in the PUF60 (poly-U-binding factor 60 kDa) gene, which is located on the long arm of chromosome 8, specifically in the q24.3 region.
View Article and Find Full Text PDFRole of diffusion tensor imaging in the evaluation of white matter integrity in idiopathic intracranial hypertension.
Headache
October 2024
Department of Radiology, Bezmialem Vakıf University Hospital, Istanbul, Turkey.
Objectives: To determine whether idiopathic intracranial hypertension (IIH) may affect white matter integrity and optic pathways by using diffusion tensor imaging (DTI) and to correlate the DTI metrics with intracranial pressure (ICP).
Methods: This study is a retrospective case-control study. A total of 42 patients who underwent lumbar puncture and those with elevated ICP, meeting the diagnostic criteria for IIH, were included in the study.
Analysis of cerebral venous sinus stenosis by flat panel angiographic CT (FP-CT) to guide treatment for idiopathic intracranial hypertension.
Interv Neuroradiol
September 2024
Department of Neurosurgery, University of Illinois at Chicago, Chicago, IL, USA.
Introduction: Cerebral venous sinus stenting (CVSS) is an effective treatment for idiopathic intracranial hypertension (IIH) secondary to dural venous sinus stenosis. Traditional selection of patients for CVSS has been made by microcatheter manometry, but pressure measurements are often equivocal. Here we present the results of a series of cases in which venous flat-panel CT (FP-CT) was used as an adjunct to microcatheter manometry to improve decision making and precise stent placement during CVSS.
View Article and Find Full Text PDFElevated systemic venous pressures as a possible pathology in prepubertal pediatric idiopathic intracranial hypertension.
Childs Nerv Syst
December 2024
Department of Neurosurgery, Aarhus University Hospital, Aarhus, Denmark.
Article Synopsis
- Pediatric idiopathic intracranial hypertension (IIH) is a rare condition with unknown causes, and this study investigated whether increased systemic or cerebral venous pressure might play a role in its development.
- The study involved 11 prepubertal children who underwent various tests, including MRI and pressure monitoring, showing all had elevated venous pressures, but only one had specific venous stenosis while others had normal anatomy.
- The findings suggest that increased systemic venous pressure could be linked to prepubertal IIH, highlighting a need for pediatric-specific diagnostic criteria and further research to understand and treat this condition better.
Management of concurrent symptomatic tuberculum sellae meningioma and idiopathic intracranial hypertension: A case report.
Surg Neurol Int
August 2024
Department of Neurosurgery, The University of Texas Health San Antonio, San Antonio, Texas, United States.
Article Synopsis
- - The text discusses a rare case of a 58-year-old male with both a symptomatic tuberculum sellae meningioma (TSM) and idiopathic intracranial hypertension (IIH), detailing the challenges of treating concurrent brain conditions.
- - The patient experienced vision loss and headaches, and imaging revealed both the brain tumor and stenosis in the transverse sinuses, indicating increased intracranial pressure.
- - A surgical approach involving tumor resection and subsequent stenting for IIH was performed, aiming to address both health issues in a way that optimized patient outcomes while reducing risks.
Therapeutic effect of a single lumbar puncture in idiopathic intracranial hypertension.
J Headache Pain
September 2024
Department of Neurology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Article Synopsis
- Idiopathic intracranial hypertension (IIH) is a neurological disorder marked by elevated intracranial pressure, with lumbar puncture (LP) used for diagnosis, although its therapeutic benefits were unclear.
- A study evaluated the effects of a single LP on people with IIH, measuring outcomes related to papilledema, visual health, and headache severity before and after the procedure.
- Results showed a significant reduction in papilledema and improvements in papilledema grading and retinal nerve fiber thickness seven days after LP, indicating potential therapeutic benefits of the procedure.
Analysis of Neuroradiologic Findings in Idiopathic Intracranial Hypertension-A Population-Based Study.
J Neuroophthalmol
September 2024
Albert Einstein College of Medicine Training Program (YNS), Bronx, New York; Department of Ophthalmology (YNS), Boston University, Boston, Massachusetts; Department of Radiology (GJP), Jacobi Medical Center, Bronx, New York; Department of Radiology (GJP), Albert Einstein College of Medicine, Bronx, New York; Department of Ophthalmology and Visual Sciences (NKR), Montefiore Medical Center, Bronx, New York; Department of Ophthalmology (NR), New York Eye and Ear Infirmary of Mt Sinai, New York, New York; Department of Medicine (FMPS), Jacobi Medical Center, Bronx, New York; Department of Ophthalmology (FMPS), Indiana University School of Medicine, Indianapolis, Indiana; Department of Research Studies (AP), University of Pennsylvania, Philadelphia, Pennsylvania; Department of Surgery (Ophthalmology) (JNM), Jacobi Medical Center, Bronx, New York; and Department of Ophthalmology and Visual Sciences (JNM), Albert Einstein College of Medicine, Bronx, New York.
Background: Idiopathic intracranial hypertension (IIH) has been associated with several MRI features. We assessed types of MRI findings and clinical-radiologic correlations in patients with IIH from one hospital system.
Methods: A retrospective chart review of IIH and control patients was conducted.
Idiopathic intracranial hypertension in Asians: a retrospective dual-center study.
J Headache Pain
September 2024
Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
Background: There have been limited data on idiopathic intracranial hypertension (IIH) in Asians and there remain uncertainties whether a cerebrospinal fluid (CSF) pressure of 250 mm CSF is an optimum diagnostic cutoff. The aims of the present study included (1) characterization of IIH patients in Taiwan, (2) comparisons among different diagnostic criteria for IIH, and (3) comparisons between patients with CSF pressures of > 250 and 200-250 mm CSF.
Methods: This retrospective study involved IIH patients based on the modified Dandy criteria from two tertiary medical centers in Taiwan.