6,428 results match your criteria: "Idiopathic Intracranial Hypertension"
Factors associated with vision loss in idiopathic intracranial hypertension patients with severe papilledema.
Eye (Lond)
October 2024
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
Background/objectives: Our aim was to compare factors associated with poor versus good visual outcomes in idiopathic intracranial hypertension (IIH) patients with severe papilledema at initial presentation.
Subjects/methods: Retrospective review of consecutive IIH patients (1/1/2013-6/10/2023) with severe papilledema (Frisén grade 4-5 and/or atrophy in at least one eye); Patients were divided into "poor visual outcome" (poor visual acuity and constricted visual field in at least one eye) and "good visual outcome" (good visual acuity and only mild visual field changes in both eyes) at >6 months for medically-treated patients and >3 months follow-up for surgically-treated patients.
Results: We included 134 IIH patients with severe papilledema (70 had poor and 64 had good visual outcomes).
Background: Children and young people living with severe obesity experience a range of complications of excess weight (CEW); however the prevalence of complications is not well defined. We have evaluated baseline characteristics and CEW of patients from two UK tier 3 paediatric weight management services.
Methods: All new patients aged 2-17 years seen from March 2022 to February 2023 were included.
Cerebrospinal Fluid Leak and Idiopathic Intracranial Hypertension in a Transgender Male: Is Intracranial Hypertension Hormonally Mediated?
Case Rep Neurol
July 2024
Department of Neurology, NYU Langone, New York, NY, USA.
Article Synopsis
Sodium bicarbonate use in the treatment of idiopathic intracranial hypertension.
Eye (Lond)
October 2024
Department of Ophthalmology & Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.
Purpose: This retrospective case-control study from 2008 to 2022 aimed to determine the effect of adjunctive sodium bicarbonate (NaHCO) on treatment outcomes of and side effects of acetazolamide (ACZ) for the treatment of idiopathic intracranial hypertension (IIH).
Subjects/methods: Retrospective data was collected via chart review. 288 eyes of 144 patients with IIH, including those taking ACZ alone (control group, n = 89) vs.
Idiopathic Intracranial Hypertension Is Associated with Recurrent CSF Leak and Reoperation for Spontaneous Temporal Encephalocele.
J Neurol Surg B Skull Base
October 2024
Department of Neurosurgery, Penn Medicine, Philadelphia, Pennsylvania, United States.
Spontaneous temporal encephaloceles (STEs) are increasingly recognized as sequelae of idiopathic intracranial hypertension (IIH), which in turn may further complicate their management. We endeavored to review the University of Pennsylvania institutional experience on operative management of STEs, with a focus on factors which may influence surgical outcomes, particularly IIH. Retrospective chart review over 9 years from 2013 to 2022.
View Article and Find Full Text PDFIdiopathic Intracranial Hypertension Induced Cervical Syringomyelia and Cerebellar Tonsillar Ectopia Reversed With Venous Sinus Stenting.
J Neuroophthalmol
October 2024
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine (JP), Plantation, Florida; and Department of Neurosurgery (EP), University of Miami Miller School of Medicine, Plantation, Florida.
Improving Diagnostic Yield in Patients with Pulsatile Tinnitus: A Ten-Year Analysis.
Laryngoscope
October 2024
Department of Otolaryngology-Head and Neck Surgery, Virginia Commonwealth University School of Medicine, Richmond, Virginia, U.S.A.
Objectives: To determine the yield of a comprehensive diagnostic algorithm for patients with pulsatile tinnitus (PT) and to review the common etiologies and present clinical pears for their diagnosis.
Methods: Retrospective chart review of patients with PT from 2013 to 2023. Charts were reviewed for demographic data (age, sex, BMI), side of PT (or bilateral), specialty clinic of initial evaluation, coexistent symptoms in addition to PT, and final diagnosis (or non-diagnosis).
Article Synopsis
- - The study investigates the long-term results of sigmoid sinus wall reconstruction (SSWR) for treating pulsatile tinnitus (PT) caused by sigmoid sinus wall anomalies (SSWAs) in patients, with a focus on outcomes lasting more than 5 years post-surgery.
- - Conducted as a retrospective review, the study included 35 out of 58 eligible patients, reporting a 97.3% short-term success rate and an 83.8% long-term success rate in alleviating PT symptoms, though 13.5% of patients experienced recurrence of symptoms later.
- - The findings conclude that SSWR is a highly effective and safe procedure for managing PT linked to SSWAs, showing minimal risk for further complications related
Intermittent spontaneous CSF rhinorrhea exacerbated by hormonal fluctuations associated with menstrual cycles.
Clin Case Rep
October 2024
Department of Otolaryngology, Head and Neck Surgery Baylor University Medical Center Dallas Texas USA.
This case underscores the importance of recognizing the potential link between hormonal fluctuations during the menstrual cycle and idiopathic intracranial hypertension (IIH), which could lead to spontaneous cerebrospinal fluid (CSF) rhinorrhea. Eliciting a history of intermittent clear rhinorrhea with the onset of menstrual cycle if presenting with menstrual migraines could allow for a more prompt diagnosis and treatment of IIH and CSF leak. Early diagnosis and intervention are crucial to prevent serious complications.
View Article and Find Full Text PDFIntracranial pressure affects retinal venular complexity in idiopathic intracranial hypertension: a retrospective observational study.
BMC Neurol
October 2024
Department of Neurology, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, China.
Article Synopsis
Epidemiology of optic disc edema in 2021/2022: Results from a cohort of 197 patients.
Rev Neurol (Paris)
October 2024
AP-HM, Hôpital de La Timone, Ophthalmology Department, Marseille, France; Aix-Marseille Université, CNRS, CRMBM, Marseille, France.
Article Synopsis
- The study aimed to identify the causes of optic disc edema from 2021 to 2022 in patients from Timone and Nord hospitals in Marseille.
- A total of 197 patients were analyzed, finding that the most common cause was intracranial hypertension (IH), affecting about 37% of cases, followed by retinal vein occlusion and edema related to uveitis.
- The research emphasizes the need for thorough assessments and the use of advanced imaging techniques to improve the diagnosis of optic disc edema.
Spontaneous lateral sphenoid cephalocele (SLSC) is the herniation of intracranial contents through a bony defect in the lateral sphenoid, without predisposing factors. SLSC pathogenesis is associated with idiopathic intracranial hypertension (IIH); however, the relationship between IIH and SLSC is not fully understood due to the limited number of published case reports. Here, we report a unique case of SLSC in a 39-year-old female who presented with a combination of a lateral sphenoid cephalocele and multiple radiologic findings indicative of IIH, some of which have never been described in previously published case reports.
View Article and Find Full Text PDFSafety and Efficacy of Metformin for Idiopathic Intracranial Hypertension. A U.S-Based Real-World Data Retrospective Multicenter Cohort Study.
medRxiv
October 2024
Montefiore-Einstein Cerebrovascular Research Lab, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Article Synopsis
An Unusual Presentation of Leber Hereditary Optic Neuropathy-Plus Case Caused by a Novel DNAJC30 Variant.
Am J Med Genet A
October 2024
Department of Pediatric Neurology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey.
Article Synopsis
- Leber hereditary optic neuropathy (LHON) is a genetic condition that primarily causes vision loss from the degeneration of retinal ganglion cells, while LHON-Plus includes additional neurological symptoms like seizures and movement disorders.
- A 15-year-old boy with atypical LHON-Plus presented with severe headaches and vision problems, leading to a misdiagnosis of idiopathic intracranial hypertension before revealing symptoms of neuromyelitis optica spectrum disorder (NMOSD).
- Genetic testing identified a novel variant in the DNAJC30 gene, highlighting the importance of exome sequencing in diagnosing complex neurological disorders that may share symptoms with other conditions like NMOSD.
Seronegative brucella meningitis diagnosed by CSF PCR: report on seven cases.
BMC Infect Dis
October 2024
Ahya Neuroscience Research Center, Tehran, Iran.
Article Synopsis
- * In a study of seven NB cases, signs of increased intracranial pressure were prominent, including symptoms like blurred vision and nerve palsy, while MRI scans revealed various brain abnormalities.
- * All patients tested negative for Brucella in blood and CSF serology, but the diagnosis was confirmed using molecular techniques like PCR, highlighting the need for these advanced methods in suspected cases of NB.
Clinical correlation of optic nerve head analysis performed by SD-OCT in children with pseudopapilledema and papilledema.
Photodiagnosis Photodyn Ther
December 2024
Assisstance Professor of Pediatric Neurology Department, Doctor Sami Ulus Pediatricand Trianing Hoapital Ankara, Turkey.
Purpose: To investigate some diagnostic indicators in optic nerve head (ONH) analysis of children with 'Pseudopapilledema' and 'Papilledema' by Spectral Domain Optical Coherence Tomography (SD-OCT).
Methods: Medical records of 52 children with optic disc swelling, who were followed up by the departments of pediatric neurology and ophthalmology between May 2018 and May 2019 were reviewed retrospectively. Cases were classified as group 1 (Papilledema secondary to Idiopathic Intracranial Hypertension) including 54 eyes of 27 cases, group 2 (Pseudopapilledema secondary to bilateral optic disc drusen) including 50 eyes of 25 cases and control group.
Advancing Patient Education in Idiopathic Intracranial Hypertension: The Promise of Large Language Models.
Neurol Clin Pract
February 2025
Chicago Medical School (QAD), Rosalind Franklin University of Medicine and Science, North Chicago, IL; Department of Ophthalmology (QAD, MZC, PHP, ABS, AME), Harvey and Bernice Jones Eye Institute; UAMS College of Medicine (ADB), University of Arkansas for Medical Sciences, Little Rock, AR; Herbert Wertheim College of Medicine (ATZ), Florida International University; Mary & Edward Norton Library of Ophthalmology (ATZ), Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; Department of Ophthalmology (TKE), Benha Faculty of Medicine, Benha University; Department of Ophthalmology (AKH), Faculty of Medicine, South Valley University, Qena; Department of Ophthalmology (OS), Research Institute of Ophthalmology, Giza, Egypt; Department of Ophthalmology (OS), Qassim University Medical City, Al-Qassim, Saudi Arabia; Department of Ophthalmology (RG, AME), Boston Children's Hospital, Harvard Medical School, MA; and Department of Ophthalmology (ABS), Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Background And Objectives: We evaluated the performance of 3 large language models (LLMs) in generating patient education materials (PEMs) and enhancing the readability of prewritten PEMs on idiopathic intracranial hypertension (IIH).
Methods: This cross-sectional comparative study compared 3 LLMs, ChatGPT-3.5, ChatGPT-4, and Google Bard, for their ability to generate PEMs on IIH using 3 prompts.
A Systematic Review of Sleep Disturbance in Idiopathic Intracranial Hypertension.
Neurol Clin Pract
February 2025
Albert Einstein College of Medicine (SK), New York, NY; Departments of Psychiatry and Behavioral Sciences (LNR, BRB, LFB, MEP) and Neurology and Neurosurgery (RMES), Johns Hopkins University School of Medicine (JSS, LY, AIE), Baltimore, MD; School of Medicine (NK), University of Connecticut, Farmington, CT.
Purpose Of Review: Sleep disturbances, particularly obstructive sleep apnea (OSA), may have a significant impact on the outcomes of patients with idiopathic intracranial hypertension (IIH). We conducted a PRISMA-compliant systematic literature review to study sleep disturbance in adult patients with IIH.
Recent Findings: The current literature on the relationship between IIH and sleep is quite limited.
The use of balloon guide catheters during venous sinus stenting: A case series.
Interv Neuroradiol
December 2024
Department of Neurosurgery, North Shore University Hospital/Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, USA.
Article Synopsis
- * A study reviewed the use of a balloon guide catheter (BGC) in 22 patients undergoing VSS, effectively aiding in stent delivery without complications.
- * The findings suggest that BGCs enhance safety and efficiency in VSS, particularly in navigating complex venous structures.
Therapy-Related Acute Promyelocytic Leukemia: Case Series and Current Insights.
Eur J Haematol
January 2025
Hematology Unit, Department of Onco-Hematology, A.O. of Cosenza, Cosenza, Italy.
Article Synopsis
- Therapy-related acute promyelocytic leukemia (t-APL) is a rare condition often arising from treatments like alkylating agents or topoisomerase II inhibitors.
- The report details three cases of t-APL at Cosenza Hospital, each requiring unique treatments following different cancer therapies.
- Notable outcomes include a complete remission in one patient treated with ATRA, while another faced severe complications but also achieved remission; the third patient, however, sadly died due to complications during treatment.
A narrative review of magnetic resonance imaging findings in pediatric idiopathic intracranial hypertension.
Health Sci Rep
October 2024
Department of Radiology School of Medicine, Birjand University of Medical Sciences Birjand Iran.
Background And Aims: Idiopathic intracranial hypertension (IIH) is a rare neurological disorder in the pediatric population which is defined as an increase in intracranial pressure (ICP) without the presence of brain parenchymal lesions, hydrocephalus, or central nervous system infection. In this study, we have determined the magnetic resonance imaging (MRI) findings in IIH patients.
Methods: A comprehensive literature search was conducted using the electronic databases including Web of Sciences, Scopus, and Pubmed to identify suitable and relevant articles using keyword search methods.
Unusual association of cervical arachnoid cyst and idiopathic intracranial hypertension.
Neurosciences (Riyadh)
October 2024
From the Division of Neurosurgery, Department of Surgery, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Article Synopsis
- - Arachnoid cysts (ACs) are usually found in the brain and are mostly symptom-free, but a rare case links symptomatic AC with idiopathic intracranial hypertension (IIH).
- - A 71-year-old man with persistent shoulder pain and brachialgia was diagnosed with a cervical arachnoid cyst, later revealing IIH during treatment.
- - The patient's cyst removal surgery was unsuccessful; however, after multiple treatments, a VP shunt was placed, alleviating his symptoms and highlighting the importance of diagnosing IIH early for effective CSF management.
Optic Nerve Sheath Fenestration: A Retrospective Review of Its Safety, Efficacy, and Impact on Optical Coherence Tomography.
Ophthalmic Plast Reconstr Surg
October 2024
Department of Ophthalmology and Visual Sciences, University of Kentucky College of Medicine, Lexington, KY.
Article Synopsis
- This study evaluated the safety and effectiveness of optic nerve sheath fenestration, focusing on visual acuity, perimetry, and optical coherence tomography in patients with papilledema and idiopathic intracranial hypertension.
- A total of 55 patients were studied post-surgery, showing significant improvements in visual acuity, perimetric mean deviation, and reduced optic disc edema after 12 months.
- The findings suggest that this surgical approach is not only safe but also helps preserve vision, with specific measurements of the macular ganglion cell layer being useful for diagnostics.