3 results match your criteria: "Ichan School of Medicine at the Mount Sinai Hospital[Affiliation]"

Article Synopsis
  • The study investigates how integrating point of care (POC) echocardiography in managing septic shock affects patient outcomes in the ICU following the Surviving Sepsis Campaign guidelines.
  • A total of 1701 articles were reviewed, and after filtering, seven studies with 3885 patients were included, showing that POC echocardiography is linked to lower in-hospital and 28-day mortality rates, more frequent use of inotropic support, and faster lactate clearance.
  • The researchers concluded that while POC echocardiography can improve some outcomes in septic shock management, more extensive studies are needed to confirm these findings and explore additional treatment effects.
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Clinical Implications of Basic Research: Exploring the Transformative Potential of Spatial 'Omics in Uro-oncology.

Eur Urol

January 2025

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address:

New spatial molecular technologies are poised to transform our understanding and treatment of urological cancers. By mapping the spatial molecular architecture of tumours, these platforms uncover the complex heterogeneity within and around individual malignancies, offering novel insights into disease development, progression, diagnosis, and treatment. They enable tracking of clonal phylogenetics in situ and immune-cell interactions in the tumour microenvironment.

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Bladder cancer is a heterogeneous disease. Treatment decisions are mostly decided based on disease stage (non-muscle invasive or muscle invasive). Patients with muscle-invasive disease will be offered a radical treatment combined with systemic therapy, while in those with non-muscle-invasive disease, an attempt to resect the tumor endoscopically will usually be followed by different intravesical instillations.

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