10 results match your criteria: "Icahn School of Medicine - Mount Sinai Hospital[Affiliation]"
Blood
March 2024
Institut de Recherche en Santé Digestive, Université de Toulouse, INSERM, INRAE, ENVT, Université Toulouse III Paul Sabatier, Toulouse, France.
As a functional component of erythrocyte hemoglobin, iron is essential for oxygen delivery to all tissues in the body. The liver-derived peptide hepcidin is the master regulator of iron homeostasis. During anemia, the erythroid hormone erythroferrone regulates hepcidin synthesis to ensure the adequate supply of iron to the bone marrow for red blood cell production.
View Article and Find Full Text PDFQual Life Res
December 2023
Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Purpose: Bowel urgency (BU) is an important symptom of Crohn's disease (CD), however there is no patient-reported outcome (PRO) scale validated in this population to assess BU severity. Here we evaluated the content validity and psychometric properties of the Urgency Numeric Rating Scale (NRS).
Method: Qualitative interviews were conducted with moderate-to-severe CD participants to confirm importance and relevance of BU in this population, cognitively debrief the Urgency NRS, and explore score interpretation and CD remission.
J Orthop
January 2023
Department of Orthopaedics, The Ohio State Wexner Medical Center, 2835 Fred Taylor.Dr, Columbus, OH, USA.
Introduction: The purpose of this study is to report a systematic review and meta-analysis of solid organ transplant (SOT) patients undergoing shoulder arthroplasty to compare functional and radiographic outcomes, demographics, and complications with non-transplant patients.
Methods: Studies were included if they examined patients undergoing shoulder arthroplasty in the setting of prior solid organ transplantation and included post operative range of motion, patient-reported outcomes, complications, or revisions. Studies were excluded if they were national database analyses or lacked clinical data.
JSES Int
May 2022
Icahn School of Medicine - Mount Sinai Hospital, Department of Orthopaedics, New York, NY, USA.
Background: Humeral head pseudosubluxation (HHPS) in relation to the glenohumeral joint is a common finding following fractures of the proximal humerus. The temporary inferior subluxation of the humeral head may be secondary to a transient axillary nerve neuropraxia, pain inhibition of the deltoid, or hemarthrosis or capsular disruption that alters the physiologically negative pressure in the glenohumeral joint. Despite the frequency of this finding, it is not well described in the literature.
View Article and Find Full Text PDFJ Shoulder Elbow Surg
September 2022
Department of Orthopaedics, Icahn School of Medicine-Mount Sinai Hospital, New York, NY, USA.
Background: Avascular necrosis (AVN) of the humeral head is a debilitating pathology that can be managed with an array of treatments depending on disease staging. Humeral head arthroplasty for AVN has demonstrated good short-term improvements in pain and range of motion, but the published long-term outcomes data are limited. The objective of this study was to report long-term survivorship and outcomes for patients undergoing hemiarthroplasty (HA) or total shoulder arthroplasty (TSA) for the treatment of AVN of the humeral head.
View Article and Find Full Text PDFJ Craniovertebr Junction Spine
June 2021
Department of Orthopedic Surgery, Icahn School of Medicine - Mount Sinai Hospital, NY, USA.
This study aims at identifying predictors of postoperative complications, lesion recurrence, and overall survival in patients undergoing en bloc spondylectomy (EBS) for spinal tumors. For this purpose a systematic review of the literature was conducted and patient-level data extracted. Linear-regression models were calculated to predict postoperative complications, lesion recurrence and overall survival based on age, tumor etiology, surgical approach, mode of resection (extra- vs.
View Article and Find Full Text PDFAcad Med
November 2020
E. Oliveros is assistant professor, medicine, Pulmonary Hypertension, Right Heart Failure and CTEPH Program, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania. At the time of this writing, she was an advanced heart failure and transplant fellow, Icahn School of Medicine Mount Sinai Hospital, New York, New York; email: Twitter:
Am J Ophthalmol Case Rep
June 2020
Department of Ophthalmology, Icahn School of Medicine Mount Sinai Hospital, 1468 Madison Ave, New York, NY, 10029, USA.
Purpose: To present a unique case of keratitis with progression to corneal perforation and endophthalmitis, in the setting of epidermal growth factor receptor inhibitor (erlotinib) therapy for advanced non-small cell lung cancer.
Observations: An 89-year-old female with non-small cell lung cancer on erlotinib presented with corneal perforation due to infectious keratitis. Microbial cultures grew a virulent pathogen known to affect immunocompromised patients that has not been previously described to cause infectious keratitis.
JACC Case Rep
October 2019
Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah.
Pharmacol Res Perspect
December 2015
Recent preclinical studies have revealed a functionally important role for the drug efflux pump P-glycoprotein (P-gp) at the blood-brain barrier in limiting brain levels and thus antidepressant-like activity of certain antidepressant drugs. Specifically, acute administration of P-gp inhibitors, such as verapamil and cyclosporin A (CsA), has been shown to augment brain concentrations and functional activity of the antidepressant escitalopram in rodents. However, depression is a chronic disorder and current treatments require prolonged administration to elicit their full therapeutic effect.
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