1 results match your criteria: "Icahn 10 School of Medicine at Mount Sinai[Affiliation]"
Drug Gene Budger (DGB): an application for ranking drugs to modulate a specific gene based on transcriptomic signatures.
Bioinformatics
April 2019
Department of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Knowledge Management Center for Illuminating the Druggable Genome, Mount Sinai Center for Bioinformatics, Icahn 10 School of Medicine at Mount Sinai, New York, NY, USA.
Summary: Mechanistic molecular studies in biomedical research often discover important genes that are aberrantly over- or under-expressed in disease. However, manipulating these genes in an attempt to improve the disease state is challenging. Herein, we reveal Drug Gene Budger (DGB), a web-based and mobile application developed to assist investigators in order to prioritize small molecules that are predicted to maximally influence the expression of their target gene of interest.
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