557 results match your criteria: "Ibrahim Cecen University[Affiliation]"

Aim: The aim of this study was to determine the relationship between COVID-19 fear and the prenatal attachment of pregnant women in the pandemic.

Method: The sample of this cross-sectional and descriptive study consisted of 377 participants aged 18-45. The study was conducted from August to December 2021 in the east of Turkey.

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Accurate knowledge of surface anatomy is essential for physical examination, invasive procedures, and anatomy education. Individual factors such as age make surface landmarks variable so accurate descriptions are needed. The aim of this study is to describe age-related surface landmarks for intrathoracic structures in children.

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Evaluation of Oxidative Stress Parameters and Genotoxic Effects in Patients With Work-Related Asthma and Silicosis.

J Occup Environ Med

February 2023

From the Department of Pulmonary Medicine and Occupational Medicine, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey (Dr Ozlem Kar); Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey (Drs Ozlem Kar, Dilsiz, and Basaran); Department of Pulmonary Medicine, Faculty of Medicine, Selcuk University, Konya, Turkey (Dr Ergun); Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Bulent Ecevit University, Zonguldak, Turkey (Anlar); Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Ibrahim Cecen University, Agri, Turkey (Ms Hazar); Department of Pulmonary Medicine, Occupational and Environmental Diseases Hospital, Ankara, Turkey (Dr Karatas); and Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Baskent University, Ankara, Turkey (Dr Basaran).

Objective: To determine the mechanistic roles of oxidative stress, inflammation, and genotoxicity parameters in patients with work-related asthma (WRA) and silicosis.

Methods: Thirty-eight healthy office workers, 27 employees with a history of exposure and no disease, 24 employees with WRA, and 23 employees with silicosis were included in this study. Superoxide dismutase, catalase, glutathione peroxidase, malondialdehyde, and interleukins (IL) 17, 23, and 27 levels were measured in the serum.

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Aim: The objective of this study was to examine the effect of delayed umbilical cord clamping on the newborn's oxygen saturation and sucking success in primiparas.

Methods: The study was conducted based on the experimental model with a control group, between March 15-November 10, 2020. The sample of the study consisted of 101 primiparous pregnant (48 primiparous with delayed cord clamping within 1-3 min and 53 primiparous with early cord clamping within 1 min) (having no high-risk pregnancy, 38-42 weeks, vaginal birth) in Turkey.

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Assessment of genetic diversity among different varieties helps to improve desired characteristics of crops, including disease resistance, early maturity, high yield, and resistance to drought. Molecular markers are one of the most effective tools for discovering genetic diversity that can increase reproductive efficiency. Simple sequence repeats (SSRs), which are codominant markers, are preferred for the determination of genetic diversity because they are highly polymorphic, multi-allelic, highly reproducible, and have good genome coverage.

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The purpose of this prospective longitudinal study was to determine the prevalence of sexual dysfunction (SD) in women in the third trimester of pregnancy and at 8 week and 6 months in the postpartum period, as well as to identify the factors affecting sexual function in the postpartum period. 110 pregnant women were included in the study. The results showed significant differences in the scores between pregnancy and 6 months after delivery and between 8 weeks and 6 months after delivery.

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Synthesis and aldose reductase inhibition effects of celecoxib derivatives containing pyrazole linked-sulfonamide moiety.

Bioorg Chem

November 2022

Dogubayazit Ahmed-i Hani Vocational School, Agri Ibrahim Cecen University, Agri 04400, Turkey; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum 25240, Turkey. Electronic address:

In this article, we report the synthesis of Celecoxib derivatives containing the pyrazole-linked sulfonamide moiety. The enzyme inhibition effects of these derivatives on aldose reductase (AR) were also investigated. The IC values of the pyrazole sulfonamide derivatives were determined to be in the range of 40.

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This study aimed to determine the correlation between stress coping styles and self-efficacy with regard to the spiritual and religious coping of mothers with disabled children. The descriptive and relational screening model was used in this study. The research was completed with 227 mothers in a private rehabilitation center at Turkey.

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Investigation of Fire Effects on Reinforced Concrete Members via Finite Element Analysis.

ACS Omega

August 2022

Ph.D., Associate Prof., Department of Civil Engineering, Atatürk University, 25240 Erzurum, Turkey.

Structural deterioration during fire leads to significant economic losses, severe injuries, and deaths. Research to accurately estimate the impact of fire on structural security and performance, and to identify ways to reduce it, has been increasing recently with capital investments in the building and infrastructure sectors. This research aims to establish a reliable algorithm for simulating the behavior of reinforced concrete (RC) beams under thermal and structural loads.

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Enzyme inhibition is a very active area of research in drug design and development. Chalcone derivatives have a broad enzyme inhibitory activity and function as potential molecules in the development of new drugs. In this study, the synthesized novel halogenated chalcones with bromobenzyl and methoxyphenyl moieties were evaluated toward the acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes and human erythrocyte carbonic anhydrase I (hCA I), and II (hCA II) isoenzymes.

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Serum paraoxonase 1 (PON1) is found in all mammalian species and is a calcium-dependent hydrolytic enzyme. PON1 hydrolyze several substrates, including carbonates, esters, and organophosphates. In the current study, we aimed to investigate the effect of the presynthesized benzohydrazide derivatives (1-9) on PON1 activity.

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Introduction: With its suitable nuclear decay characteristics and large-scale production feasibility with adequate specific activity, Lu is regarded as an excellent radionuclide for developing bone pain palliation agent. Ethylenediamine-tetramethylene phosphonic acid (EDTMP) is a preferred carrier molecule for radiolanthanides, such as Lu. The present paper describes the synthesis of EDTMP and the development of a ready-to-use kit for the preparation of Lu-EDTMP and its quality control in accordance with the quality and safety criteria required for medicinal use.

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Beans are legumes that play extremely important roles in human nutrition, serving as good sources of protein, vitamins, minerals, and antioxidants. In this study, we tried to elucidate the genetic diversity and population structure of 40 Turkish bean ( L.) local varieties and 5 commercial cultivars collected from 8 different locations in Erzurum-Ispir by using inter-primary binding site (iPBS) retrotransposon markers.

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Brain tumors are one of the most dangerous diseases that affect human health and maybe result in death. Detection of brain tumors can be made by using biopsy. However, this is an invasive procedure.

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The possible beneficial impacts of evodiamine on hepatotoxicity induced by cisplatin.

Environ Sci Pollut Res Int

December 2022

Department of Biochemistry, Faculty of Medicine, Aksaray University, Aksaray, Turkey.

In this, it was aimed to determine the possible beneficial effects of evodiamine on hepatotoxicity induced by experimental cisplatin administration in rats. For this purpose, experimental animals were divided into four groups (n=6). Groups were designed as control, evodiamine (EVO), cisplatin (CIS), and evodiamine+cisplatin (EVO+CIS) groups.

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Purpose: To investigate vascular endothelial growth factor (VEGF) and proliferating cell nuclear antigen (PCNA) immunoreactivities, as well as apoptosis and oxidative stress levels in Streptozotocin (STZ)-induced diabetic rats, and determine how neferine affected these parameters.

Methods: Thirty-five male Sprague Dawley rats were divided into five groups of seven. Fasting blood glucose was measured 72 h after diabetes mellitus (DM) induction in 21 rats using 60 mg/kg STZ dissolved in 0.

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In this research, a series of N-phenylsulfonamide derivatives (1-12) were designed, synthesized, and investigated for their inhibitory potencies against carbonic anhydrase isoenzymes I, II, and IX (hCA I, hCA II, and hCA IX) and cholinesterases (ChE), namely, acetylcholinesterase and butyrylcholinesterase. These compounds, whose inhibition potentials were evaluated for the first time, were characterized by spectroscopic techniques ( H- and C-NMR and FT-IR). CA isoenzyme inhibitors are significant therapeutic targets, especially owing to their preventive/activation potential in the therapy processes of some diseases such as cancer, osteoporosis, and glaucoma.

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In the current study, some phenolic compounds, including acteoside, isoacteoside, echinacoside, and arenarioside purified and characterized from Plantago subulata. These compounds were tested for its antioxidant potential, including Fe and Cu reductive ability and Fe chelating effects. The inhibitory effects of isolated phenolic compounds were tested towards human carbonic anhydrase I and II isoenzymes (hCA I and hCA II), butyrylcholinesterase (BChE) acetylcholinesterase (AChE), aldose reductase (AR) and α-glycosidase (α-gly).

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Hesperidin is a prominent flavanone found in citrus fruits that has a broad range of biological effects, including anti-inflammatory and antioxidant capabilities. The study's objective was to evaluate the effects of hesperidin supplementation on anti-inflammatory and antioxidant parameters such as MDA, TAC, GSH, SOD, and CAT; CRP, TNF-α, IL-6, and IL-4 levels respectively, by analyzing human intervention trials. Google Scholar, PubMed, grey literature databases, and the ClinicalTrials website were scanned to identify eligible studies.

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This study focused on a moderated mediation model. First, it determined the mediating effect of COVID-19 preventive behaviors between fear of COVID-19 and satisfaction with life. Next, it examined whether personal growth initiative moderated the mediation effect.

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Drivers of technology adoption during the COVID-19 pandemic: The motivational role of psychological needs and emotions for pre-service teachers.

Soc Psychol Educ

June 2022

Department of Computer Education & Instructional Technology, Faculty of Education, Anadolu University, Eskişehir, Turkey.

The vital role of motivation becomes even more evident when considering the digital transformation of learning and teaching environments, especially with the effect of the pandemic. Basic psychological needs and emotions, which have not been comprehensively examined together despite their important roles in motivating, draw attention. Accordingly, this study aims to reveal the psychological, emotional, and individual variables that influence the pre-service teachers' intention to use technology, and to evaluate and validate the predictive power of a proposed model.

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Purpose: Five different types of synthesized azadispiro derivatives have been analyzed for radiation absorption capacity and determined their potential to be exploited as substances for a drug to be developed against radiation has been investigated.

Material And Methods: Fast neutron attenuation parameters like the effective mean free path, half-value layer (HVL), removal cross-sections, and neutron transmission number were found with the Monte Carlo simulation Geometry And Tracking (GEANT4) code. Gamma radiation absorption parameters, such as effective atom number (), mean free path (MFP), mass attenuation coefficient (MAC), and half-value layer (HVL) were theoretically determined with WinXCom software.

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To date, research on refugee mental health has mainly focused on understanding the absence of psychopathology rather than on their well-being and associated positive aspects. The aim of this study was to examine the role of resilience, hope, belongingness, and social support in predicting satisfaction with life and flourishing among 361 minority Syrian refugees living in Iraq (age range = 18-60 years, mean = 32.57,  = 10.

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Article Synopsis
  • Coumestrol is a phytoestrogen and polyphenolic compound known for its presence in various plants, and this study explores its potential health benefits, including antioxidant properties and effects on metabolic enzymes linked to diseases like Alzheimer's and diabetes.
  • The study employed different antioxidant activity assays such as DPPH, ABTS, and others, comparing Coumestrol’s effectiveness to established antioxidants like BHA and Trolox, showing a strong ability to scavenge free radicals.
  • Coumestrol also demonstrated significant inhibitory effects on important metabolic enzymes related to Alzheimer's, glaucoma, and diabetes, indicating its potential therapeutic applications in these conditions.
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