The Effect of Supplemental Nursing System on Sucking Success, Weight Gain Findings and Bilirubin Level in Newborns: A Randomized Controlled Trial.

Purpose: The aim of this study is to determine the effect of supplemental nursing system on, sucking success, weight gain findings and bilirubin levels in newborns.

Design And Methods: The study was conducted as a randomized controlled trial. The population of the research consisted of 71 infants who received care and treatment at the Neonatal Intensive Care Clinic of the hospital located in a province in eastern Turkey between February and June 2023.

Attitudes of Adolescents Toward Addictive Substances: Hope and Self-Control as Protective Factors.

: Experiences of ostracism may be related to attitudes toward substance abuse. However, the protective factors underlying this relationship are still unclear. Therefore, based on the Need-threat and Self-control theory, we aimed to test a model in which self-control and hope mediate the relationship between ostracism and attitudes toward addictive substances.

The relationship of future anxiety with a multidimensional framework of well-being among undergraduate students: optimism and pessimism as mediators.

Background: Enhancing and maintaining well-being is of great importance for university students to improve their future lives. Therefore, determining the factors that promote well-being is essential. This study aimed to examine the mediating roles of optimism and pessimism in the association between future anxiety and well-being after controlling gender, age, faculty, and department.

Breastfeeding Attitudes and Milk Production of Mothers Staying in Single and Double Rooms after Birth: A Cross-Sectional Comparative Study.

There is limited evidence on whether the interaction of mothers staying in double rooms (DRs) in the hospital after birth affects breastfeeding attitudes and milk production. To compare the breastfeeding attitudes and milk production of mothers staying in a DR in the hospital after birth with mothers staying in a single room (SR). In the study, 181 mothers who gave birth at term were included.

Antimycobacterial activity of luteolin in resistant Mycobacterium tuberculosis isolates and cytotoxicity on L929 cells.

Mycobacterium tuberculosis (M. tuberculosis) bacteria can cause oxidative stress and the production of inflammatory cytokines, creating an environment that enhances tumour formation, progression and metastasis. Epidemiological studies have found a link between lung cancer and tuberculosis (TB), but the cellular mechanism is still unclear.

The mediating roles of perceived social support and resilience in the relationship between earthquake anxiety and traumatic experiences among earthquake survivors in Turkey.

Background: The devastating earthquakes that struck Turkey have left profound psychological impacts on those affected, with anxiety and trauma being particularly prevalent. Understanding the factors that can mitigate these effects is important for developing effective interventions.

Objective: This study seeks to analyse the intermediary functions of perceived social support (PSS) and resilience within the correlations linking earthquake-induced anxiety and the occurrence of traumatic experiences after the seismic event in Turkey.

Impact of the COVID-19 pandemic on the mental health of Nursing students: A systematic review and meta-analysis.

Background: There is an increased prevalence of mental health problems in various population groups as a result of the COVID-19 pandemic and its consequences, especially regarding anxiety, stress, depression, fear, and sleep disturbances, require to be investigated longitudinally.

Objective: This study aimed to determine the impact that the COVID-19 pandemic had on the mental health of Nursing students, as well as to examine other associated factors such as anxiety, fear, sleep disturbances, and coping strategies.

Method: This systematic review and meta-analysis were designed following the PRISMA guidelines and were registered in PROSPERO with code CRD42024541904.

Unveiling Risk Profiles: A Latent Profile Analysis of 21st-Century Skills, Resistance to Change, and Cognitive Flexibility.

Objectives: Limited research utilized a person-centered approach in examining 21st-century skills. This study used latent profile analysis to explore the relationships between resistance to change, cognitive flexibility, and 21st-century skills, including creativity, cooperativity, critical thinking, communication, and problem-solving.

Materials And Methods: A convenience sampling approach was used to recruit 502 individuals (342 females; mean = 21.

mTOR Pathway Inhibition, Anticancer Activity and In Silico Calculations of Novel Hydrazone Derivatives in Two- and Three-Dimensional Cultured Type 1 Endometrial Cancer Cells.

Background: Endometrial cancer remains a significant health concern, with type 1 endometrial cancer characterized by aberrant expression of estrogen-dependent and mTOR pathway proteins. In this study, we evaluated the effects of two novel hydrazone derivatives against the Ishikawa cell line, a model for endometrial cancer.

Methods: Two novel hydrazone derivatives, MVB1 and MVB2, were synthesized and characterized.

Mediating role of psychological well-being in the effect of spirituality on attitudes toward death in the elderly.

Background: Spirituality and psychological well-being are important in shaping attitudes toward death.

Objective: This study was conducted to determine the mediating role of psychological well-being in the effect of spirituality on attitudes toward death in the elderly.

Method: This cross-sectional descriptive study was conducted in a province of Turkey between February 2024 and June 2024 with 467 individuals aged 65 years and older.

Development of Dermal Lidocaine Nanosuspension Formulation by the Wet Milling Method Using Experimental Design: In Vitro/In Vivo Evaluation.

Lidocaine (LID), frequently used in dermal applications, is a nonpolar local anesthetic agent that is practically insoluble in water. The main aim of this study is to develop the nanosuspension formulation of LID using the design of experiments (DoE). The improved solubility and dissolution rate provided by nanosizing are expected to result in enhanced dermal bioavailability.

Chemical Composition, Antimicrobial, and Enzyme Inhibitory Properties of Elaeagnus angustifolia L.

Research on natural antioxidants derived from plants has surged due to their potential health benefits. In the current study, the chemical composition, enzyme inhibitory activity, and antimicrobial effects of the Elaeagnus angustifolia L. plant, including leaves, flowers, and flower stalk (FS) extracts, were analyzed.

Caftaric acid attenuates kidney and remote organ damage induced by renal ischemia-reperfusion injury.

Oxidative stress and inflammation are indispensable components of ischemia-reperfusion (IR) injury. In this study, we investigated the effects of low and high doses of caftaric acid (CA) on reducing kidney and remote organ damage induced by IR. We divided Wistar rats into four groups: sham, IR, low (40 mg/kg body weight (BW)), and high (80 mg/kg BW) CA groups.

Protective Effects of Baicalein and Bergenin Against Gentamicin-Induced Hepatic and Renal Injuries in Rats: An Immunohistochemical and Biochemical Study.

Background: Drug-induced organ toxicity is a significant health concern, with gentamicin known for its effective antibacterial properties but also severe side effects, particularly cytotoxicity in liver and kidney tissues. This current study observed the preventive role of baicalein and bergenin against hepatic and renal injuries caused by gentamicin in rats.

Methods: Thirty-two male Sprague Dawley rats were divided into four groups, namely, control, gentamicin (gentamicin 80 mg/kg/day), baicalein (gentamicin 80 mg/kg/day + baicalein 100 mg/kg/day) and bergenin (gentamicin 80 mg/kg/day + bergenin 100 mg/kg/day).

The effect of educational intervention through sending emails on improving physical posture in female computer users of Eastern Iran: a quasi-experiment study.

Background: Musculoskeletal disorders are among the most common occupational injuries and disabilities in developing and industrialized countries. This study aims to determine the effectiveness of e-mail training to improve the physical posture of female computer users at Birjand University of Medical Sciences in Iran.

Methods: The present interventional research explores the effect of email-based training to correct the body posture of female computer users in Birjand, Iran.

Sex differences in clinical and polysomnographic features of obstructive sleep apnea: The Turkish sleep apnea database (TURKAPNE) cohort.

Background: Previous reports from relatively small clinical cohorts have suggested that the clinical presentation of obstructive sleep apnea (OSA) differs between men and women.

Objective: We aimed to explore sex differences in clinical and polysomnographic features of OSA in a large nationwide registry.

Methods: Participants from the ongoing Turkish Sleep Apnea Database (TURKAPNE) Study from 34 centers were included in the current analysis.

Assessment of sinapic acid's protective effects against ethanol-induced gastric ulcers in rats.

This study evaluates the protective effects of sinapic acid (SA), a polyphenolic compound with diverse biological activities, against ethanol-induced gastric ulcers in rats. A gastric ulcer model was established using ethanol (ETH), and the experimental groups received either omeprazole (OMEP, 20 mg/kg) or SA at doses of 20 mg/kg and 40 mg/kg via oral gavage for 14 days. Biochemical markers, including total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), malondialdehyde (MDA), and myeloperoxidase (MPO) activity, were assessed alongside proinflammatory cytokines (tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), and IL-6) using ELISA.

An overview of patients with intertrochanteric femoral fractures treated with proximal femoral nail fixation using important criteria.

Background: This study aimed to assess important criteria, including osteoporosis, fracture type, implant position within the bone, fracture reduction, and radiographic union, in patients with intertrochanteric femoral fractures treated with proximal femoral nail (PFN) fixation and to show their effect on clinical outcomes.

Methods: PFN fixation was applied in 73 patients (41 females, 32 males; mean age: 64.5 ± 6.

Validity and reliability study of the Turkish version of the quiet quitting scale in healthcare workers.

This study aimed to assess the reliability and validity of the Turkish version of the Quiet Quitting Scale (QQS) among healthcare workers. After completing the language validation, the psychometric properties of the QQS were tested on a sample of 542 healthcare workers from two hospitals in Turkey. Convergent validity was examined using the Burnout Measure-Short Version (BMS).

β-Arbutin and cisplatin: A combined approach to modulating apoptosis, cell viability, and migration in bladder cancer cells.

One of the preferred treatments for bladder cancer, one of the most common cancers worldwide, is cisplatin-based chemotherapy. Since most tumor cells show cisplatin resistance, it is very important to discover new agents without adverse side effects. β-arbutin, a hydroquinone-β-D-glucopyranoside, has biological properties such as antioxidant, antimicrobial, anti-inflammatory, and anticancer, and is a phytochemical widely used as a skin whitener.

The Effect of Mother's Breastsleeping Behavior on Attachment and Postpartum Sleep Quality.

Background: Nowadays, the increasing importance of mother-infant contact, the significant impact of mother and baby's sleep quality, and the positive effects on breastfeeding are factors that make breastfeeding sleep important.

Aim: The aim of this study was to examine the effect of mothers' breastsleeping behavior on attachment and postpartum sleep quality.

Methods: This study is cross-sectional.

Relationship between post traumatic stress disorder and hand dimensions and hand grip strength in children aged 8-12 exposed to earthquakes.

Earthquakes cause severe destruction in the region where they occur. Children and adolescents are the group most affected group by earthquakes, and Post-Traumatic Stress Disorder is most common in this group. The age-related increase in Grip Strength varies between childhood and early adolescence.