156 results match your criteria: "Ibn Sina university hospital center[Affiliation]"

Mesonephric-like adenocarcinoma of the ovary: a case study.

J Surg Case Rep

January 2025

Department of Pathology of the National Institute of Oncology, Ibn Sina University Hospital Center, Allal Al Fassi Avenue, Rabat 10100, Morocco.

Mesonephric-like adenocarcinoma (MLA) is a rare and newly recognized subtype of ovarian and endometrial carcinomas, introduced in the 2020 World Health Organization Classification. This tumor likely originates from Müllerian-derived tissues and often mimics more common ovarian cancers, leading to frequent misdiagnosis. This case study details a 36-year-old woman who presented with urinary symptoms following a hysterectomy.

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Introduction Awake brain surgery (ABS) is a groundbreaking technique that not only enhances tumor resection but also preserves vital neurocognitive functions, particularly through advanced brain mapping. Despite its success in adults, ABS in pediatric patients remains significantly underexplored, especially concerning the role of speech-language pathology (SLP) in these procedures. This study addresses this gap by providing a thorough examination of SLP interventions in pediatric ABS across various university hospitals, including those in Morocco and internationally.

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Bilateral vertebral artery dissections account for only 8% of all vertebral artery dissections and cause just 2% of all ischemic strokes. They can occur spontaneously, even without any triggering factor. Classical clinical findings, such as headache or neck pain, may be absent, particularly in the context of a stroke.

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Introduction And Importance: Tuberculosis (TB) remains a significant public health issue, especially in developing countries where its incidence is rising due to factors like overcrowding and immunosuppression. Among extrapulmonary TB forms, abdominal TB is common, while retroperitoneal TB is rare and often challenging to diagnose due to its similarity to other retroperitoneal tumors. Diagnosis typically requires invasive procedures such as laparoscopy or laparotomy.

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An anomalous origin of the right coronary artery from the opposite sinus (R- ACAOS) with interarterial course is a very rare congenital anomaly with an increased risk of sudden cardiac death. A 29-year-old woman was admitted for exertional angina pectoris. A coronary computed tomography angiography with 3D multiplanar reconstruction revealed an R-ACAOS running between the aorta and pulmonary artery with high anatomical features and no ischemia-induced at the stress test.

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Introduction And Importance: In Morocco, diagnosing Gamma Sarcoglycanopathies mainly relies on histopathological analysis of muscle biopsies due to limited genetic and molecular research access. This study highlights the significance of muscle biopsies and explores potential predictive factors and possible correlation between histopathological abnormalities and clinical phenotypes.

Case Presentation: Muscle biopsies of six patients diagnosed with γ-sarcoglycanopathy were collected over two years.

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The rare coexistence of gastric and esophagus squamous cell carcinoma: a case report.

Pan Afr Med J

December 2024

Department of Hepatogastroenterology and Proctology Medicine B, Ibn Sina University Hospital Center, Mohamed V University of Rabat, Rabat, Morocco.

Squamous cell carcinoma (SCC) of the stomach is a rare entity with fewer than 100 cases of primary SCC reported in the literature, while esophageal SCC is prevalent and more common. However, a synchronous squamous cell carcinoma found in the esophagus and stomach remains very uncommon. We present the case of a 64-year-old with a history of dysphagia who had an endoscopy that showed an impassable stenosis of the middle esophagus, with histopathology in favor of an esophagus squamous cell carcinoma.

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Traditionally reflecting critical stenosis of the proximal left anterior descending (LAD) artery, Wellens' syndrome (WS) is an electrocardiogram (ECG) pattern of biphasic or deeply inverted T waves in leads V2 and V3. This critical stenosis can progress to an extensive anterior myocardial infarction (MI) if early and appropriate management is not received promptly. The diagnosis of severe stenosis of the LAD coronary artery can be made by using electrocardiographic changes in Wellens' syndrome.

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Two Moroccan Families with Emery-Dreifuss Muscular Dystrophy and Report of a Novel Pathogenic Variant.

Mol Syndromol

December 2024

Research team in genomics and molecular epidemiology of genetic diseases, Genomics Center of Human Pathologies, Faculty of Medicine and Pharmacy, University Mohammed V of Rabat, Rabat, Morocco.

Article Synopsis
  • - Emery-Dreifuss muscular dystrophy (EDMD) is a neuromuscular disorder that leads to muscle weakness and heart problems, mainly caused by mutations in specific genes, identified through next-generation sequencing (NGS).
  • - The study examined two Moroccan patients with EDMD, revealing one with a known splicing variant and another with a new frameshift variant, along with testing relatives for carrier status.
  • - The findings highlight NGS as crucial for accurately diagnosing EDMD, managing patient care, and providing genetic counseling to affected families.
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Article Synopsis
  • Enterovirus infections can impact the central nervous system, causing conditions like meningitis and encephalitis, and this study aimed to detail these infections for Moroccan patients.
  • Conducted from January 2021 to March 2023 at Ibn Sina University Hospital, the study analyzed 1,479 cerebrospinal fluid samples, finding enterovirus in just 19 patients, mostly young children and males.
  • Common symptoms included fever and headache, and while many cases showed lymphocytic patterns in CSF analysis, some results could mimic bacterial infections, highlighting the importance of using multiplex PCR for accurate diagnosis.
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Neuro-Behçet leading to coma: A case report.

Radiol Case Rep

January 2025

Central Radiology Department, Ibn Sina University Hospital Center, Mohamed V University of Rabat, Rabat, Morocco.

Neuro-Behçet disease is often difficult to diagnose due to its complex and severe clinical presentation. This article reports the case of a 35-year-old female patient with a history of Behçet's disease, admitted for a deep coma. Brain MRI performed upon admission revealed extended lesions in the basal ganglia, thalami, and midbrain, along with leptomeningeal contrast enhancement in the temporal region, suggesting meningoencephalitis compatible with parenchymal involvement of neuro-Behçet's disease.

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Article Synopsis
  • * Imaging techniques, especially ultrasound, are essential for detecting this condition due to their effectiveness in identifying its specific features.
  • * A case study of a 9-month-old boy demonstrated colocolic intussusception with no clear cause, leading to tissue damage that required surgical removal and reconnection of the affected colon segments.
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Persistent primary vitreous: A report on 2 rare pediatric cases.

Radiol Case Rep

January 2025

Department of Pediatric Radiology, Children Hospital of Rabat, Ibn Sina University Hospital Center, Faculty of Medicine and Pharmacy of Rabat, Rabat, Morocco.

Persistence of the fetal vasculature (PFV) is a rare ocular malformation of unknown origin, characterized by a spectrum of complex presentations with varying functional prognoses. We reported the cases of 2 male patients: a 3-month-old infant and a 4-year-old child. A thorough examination of their eyes, often requiring general anesthesia, is essential for diagnosis.

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Marchiafava-Bignami disease is a rare neurological condition characterized by necrosis and demyelination of the corpus callosum, typically associated with chronic alcoholism and/or malnutrition. The clinical manifestations of Marchiafava-Bignami disease are diverse and often nonspecific. Diagnosis of Marchiafava-Bignami disease relies on magnetic resonance imaging findings, which reveal significant and symmetrical involvement of the corpus callosum.

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Dyspnea and hemoptysis revealing Behçet's syndrome: Pulmonary artery aneurysms in a case report.

Radiol Case Rep

January 2025

Emergency Radiology Department, Ibn Sina University Hospital Center, Mohammed V University, Rabat, Morocco.

Article Synopsis
  • * A 27-year-old man presented with breathing difficulties and coughing up blood; imaging revealed dangerous pulmonary artery aneurysms.
  • * Effective diagnosis typically requires CT pulmonary angiography, and treatment options include immunosuppression, surgery, or embolization in severe cases to manage complications like significant bleeding.
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Dermoid cysts represent the most frequent type of orbital cystic lesions observed in children. While superficial orbital dermoid cysts manifest early in life as slowly growing masses, deep dermoid cysts typically remain clinically undetectable until adolescence or adulthood, at which point they enlarge and induce proptosis. Imaging studies play a pivotal role in precisely determining location and size, excluding intracranial and intraorbital extensions, and facilitating the planning of management strategies for complex cases.

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Microcephaly is defined as an occipitofrontal head circumference two standard deviations (2SD) below average for age and sex, with severe microcephaly below three standard deviations (3SD). Congenital toxoplasmosis is one of the congenital infections that can potentially lead to microcephaly. It reflects neurotropism for fetal central nervous system (CNS) cells from toxoplasma, causing massive destruction of neural tissue, resulting in serious neurological damage.

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Hydatidosis, caused by the larval form of the parasite , is a rare condition, especially in pediatric patients, with pleural involvement being exceedingly uncommon. We report a case of primary pleural hydatidosis in a 9-year-old child, emphasizing the importance of various imaging techniques in establishing an accurate diagnosis.

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Patient Safety in Anesthesiology: Progress, Challenges, and Prospects.

Cureus

September 2024

Epidemiology and Public Health, Laboratory of Community Health, Preventive Medicine and Hygiene, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.

Article Synopsis
  • - Anesthesiology has evolved significantly through advancements in technology and pharmacology, enhancing patient outcomes and enabling complex surgeries, but it still faces challenges and risks for both patients and healthcare professionals.
  • - The specialty is particularly challenged in low and middle-income countries, where collaborative actions and initiatives are essential to improve safety and access to anesthesia.
  • - Emerging technologies like simulation, genomics, artificial intelligence, and robotics offer potential solutions for enhancing patient safety in anesthesiology, but require careful ethical oversight and reliable research to maximize their benefits.
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Superior Vena Cava Syndrome Revealing Sarcoidosis a Decade Later: A Case Report.

Cureus

September 2024

Department of Pulmonology, Ibn Sina University Hospital Center, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, MAR.

Article Synopsis
  • * The case involves a 54-year-old woman who initially had treatment for tuberculosis and later developed superior vena cava syndrome (SVCS) with an unclear cause.
  • * In 2023, she was diagnosed with mediastino-pulmonary sarcoidosis type II but remained stable without needing specific treatment, highlighting that while malignancies typically cause SVCS, benign conditions like sarcoidosis should also be considered.
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Article Synopsis
  • Hemophilia is a medical condition where a person has trouble stopping bleeding because their body doesn't have enough special proteins called coagulation factors.
  • People with hemophilia can easily get bruises and bleeding in their joints, which can cause serious long-term problems in how their joints work.
  • Doctors can diagnose hemophilia through blood tests and use MRI scans to see how the disease is affecting the bones and joints, as shown in two cases of patients with very similar symptoms.
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Cystic lymphangioma is a benign lymphatic malformation that primarily affects children, with rare occurrences in adults. These malformations are most commonly found in the head and neck region, though their presence in the abdominal cavity is infrequent. In this report, we present the case of 71-year-old women with a cystic lymphangioma located in the omental bursa.

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Article Synopsis
  • Textilomas, or gossypibomas, are rare but serious complications from forgotten surgical sponges that can cause inflammatory reactions, abscesses, and are often mistaken for tumors like sarcomatoid carcinoma.
  • In a case study involving a 58-year-old woman with back pain and a retroperitoneal mass, imaging misidentified the mass as a tumor, but surgery revealed it was actually a textiloma.
  • Accurate diagnosis relies on medical history and imaging techniques, such as CT and MRI, and despite the reduced incidence due to radio-opaque sponges, careful counting remains necessary to prevent these complications.
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Disease activity score for still's disease.

Clin Rheumatol

November 2024

Internal Medicine Department, Faculty of Medicine, University of Algiers 1, Bab El Oued University Hospital Center, Said Touati Street, 16000, Bab El Oued, Algiers, Algeria.

Objective: To develop the Still's Disease Activity Score (SDAS).

Methods: We used data from the prospective adult-onset Still's disease cohort study and evaluated the disease activity. An expert group selected the most frequent, reproducible, and objective variables significantly modified in statistical analysis when comparing patients in the active group and in the remission group.

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Article Synopsis
  • Multiple primary malignancies can develop in adults simultaneously (synchronous) or at different times (metachronous).
  • Retroperitoneal liposarcoma is a rare cancer from fat tissue, while gastric adenocarcinoma is among the most common cancers globally.
  • The case report details a 52-year-old man with both malignancies, highlighting it as only the second known instance ever documented.
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