901 results match your criteria: "Ibn Sina hospital[Affiliation]"

Granulosa tumors are rare tumors arising from the cells of the sexual cord and stroma of the ovary. They account for 5% of ovarian cancers and 70% of stromal cancers of the sex cords. Retroperitoneal tumors (RPTs) are also rare and develop in the retroperitoneal and subperitoneal space.

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Cryoglobulinemic vasculitis is a rare small-vessel vasculitis leading to multi-organ dysfunction, often associated with chronic infections like hepatitis C virus (HCV), and autoimmune disorders. Most cases involve mixed monoclonal or polyclonal immunoglobulins, presenting symptoms such as purpura, arthralgias, and weakness. Severe organ involvement, particularly cardiac, is rare but potentially life-threatening.

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Article Synopsis
  • The study focuses on the outcomes of aortic valve replacement (AVR) in young Moroccan patients with severe aortic regurgitation and impaired left ventricle function.
  • A total of 42 out of 110 patients with significant aortic regurgitation and an ejection fraction of ≤35% underwent AVR, showing a low immediate postoperative mortality rate of 4.7%.
  • Long-term follow-up indicated a high survival rate of 86.8% after 15 years, along with significant clinical improvements and increased left ventricle ejection fraction post-surgery.
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Introduction: Multilocular cystic nephroma is an uncommon condition with only few cases described in the literature, although its benign nature is well-recognized.

Case Presentation: We present a case of a 28-year-old male patient who presented with a right flank pain, imaging suspected a multicystic renal cell carcinoma. A radical nephrectomy was performed view the size of the cyst and the high tumor complexity, which histology confirmed the diagnosis of multilocular cystic nephroma.

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Emergency departments (EDs) encounter substantial challenges during peak vacation periods, including increased patient volumes, limited access to medical histories, language and cultural barriers, insurance complexities, and disruptions in continuity of care. These factors strain emergency department operations, resulting in prolonged wait times, diagnostic errors, and compromised care quality. This study reviews the literature to identify patient satisfaction indicators and common challenges and evaluate strategies to improve patient outcomes during vacation-related emergency department visits.

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Background: Sleep disorders are a common health problem that can be classified into many types that are distinguished by their history and characteristics. In this case report, we discuss a case of a patient suffering from recurrent unusual prolonged sleep attacks lasting up to 9 days that responded excellently to levetiracetam.

Case Presentation: An 18-year-old Syrian male patient presented to the neurology department complaining of recurrent prolonged sleep episodes lasting for 9 days.

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Introduction The objectives of this study are to assess the knowledge, attitudes, and practices of patients with chronic inflammatory rheumatism (CIR) about diet. Aiming to identify their level of understanding of the role of nutrition in symptom management, explore their perceptions about different types of foods, and analyze their current dietary habits. The study also aims to assess the impact of this knowledge and dietary changes on their CIR management.

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Mesenteric desmoid tumor in its cystic form: Case report of a very rare variant.

Radiol Case Rep

February 2025

Department of Surgery « A », Ibn Sina Hospital, Mohammed V University, Faculty of Medicine and Pharmacy, Rabat, Morocco.

Desmoid tumors, also known as deep fibromatosis or desmoid-type fibromatosis, represent a rare subset of deep fibromatoses. It is a locally aggressive tumor, with no specific symptoms, and no metastatic potential. We report a case of a 38-year-old male patient with an abdominal mass.

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Background: Isolated sphenoid sinus fungal mucoceles are extremely rare and potentially associated with visual disturbances, cranial nerve (CN) deficits, or pituitary dysfunction. Their initial symptoms are often absent or nonspecific, and routine examination offers little information, resulting in diagnostic and therapeutic delays. A high index of suspicion and a thorough understanding of their clinical presentation, neuroradiological features, microbiological implications, and complication profile are crucial for early diagnosis and prompt management.

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 an opportunist pathogen mainly isolated in healthcare-associated infections, is a rare cause of infective endocarditis (IE) that generates an increased mortality rate compared to the usual agents. We report a case of a 70-year-old male patient who underwent a mitral valve replacement and was readmitted two months later with a high-grade continuous fever and deterioration of the general status. The diagnosis of early IE due to was established upon further investigation.

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Golimumab-Induced Anti-NuMA-1 (Nuclear Mitotic Apparatus Protein 1) Antibodies in a Rheumatoid Arthritis Patient: A Case Report.

Cureus

November 2024

Department of Rheumatology B, Ayachi Hospital, Ibn Sina Hospital Center, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.

Anti-nuclear mitotic apparatus (NuMA) 1 antibodies are uncommonly detected in routine antinuclear antibody (ANA) screening. We present the case of a 65-year-old female with rheumatoid arthritis undergoing golimumab biotherapy who developed lupus-like symptoms including photosensitivity, fatigue, weakness, myalgias, alopecia, oral ulcers, and worsening of arthritis. Elevated serum levels of NuMA-1 antibodies were detected using indirect immunofluorescence (IIF) on HEp-2 cells with a titer of 1:1000, but no other ANA patterns were associated.

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Background: Congenital intracranial immature teratoma is a rare tumor that is present in the first year of life. It is composed of three embryonic germ layers. These tumors are mainly manifested by hydrocephalus.

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Role of macroscopic on-site evaluation of endoscopic ultrasound-guided fine-needle aspiration/biopsy: Results of a multicentric prospective study.

World J Gastrointest Endosc

November 2024

Department of Gastroenterology and Endoscopy Center, Cheikh Khalifa International University Hospital, Mohammed VI University of Sciences and Health, Casablanca 82403, Casablanca-Settat, Morocco.

Article Synopsis
  • The study evaluates the effectiveness of macroscopic on-site evaluation (MOSE) during endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/FNB) in diagnosing solid lesions, particularly focusing on histological core sample adequacy.
  • Conducted across 16 medical centers in Egypt, Iraq, and Morocco, the study involved over 1000 patients and revealed that a significant majority of biopsied samples were adequate for histological evaluation, demonstrating a high diagnostic yield.
  • Results indicated that FNB needles performed best in terms of sensitivity and sample quality, highlighting the potential of MOSE as a valuable alternative to traditional rapid on-site evaluation methods.
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Background: For individuals with multiple sclerosis (MS), treatment interruption can result in relapse/recurrence of the disease activity. Currently, there are no consensus guidelines about whether an abrupt stop with a short washout period or gradual tapering is better for fingolimod (Gilenya) cessation. We investigated the impact of the fingolimod discontinuation strategy on the recurrence of disease activity and the rebound occurrence of symptoms during washout.

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Pediatric onset multiple sclerosis in Kuwait.

Clin Neurol Neurosurg

January 2025

Department of Neurology, Ibn Sina Hospital, P.O. Box 25427, Safat, 13115, Kuwait; Department of Neurology and Psychiatry, Minia University, P.O. Box 61519, Minia 61111, Egypt. Electronic address:

Background: Epidemiological data of pediatric-onset multiple sclerosis (POMS) in the Middle East is limited.

Objective: To determine the demographic and clinical characteristics of POMS in Kuwait.

Methods: A retrospective study was conducted to assess the clinical characteristics of multiple sclerosis (MS) patients who disease onset started at age < 18 years and fulfilled the International Pediatric MS Study Group (IPMSSG) criteria for MS.

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Introduction: Urethral caruncle is a benign lesion located at the urethral meatus, predominantly affecting postmenopausal women. Though often asymptomatic, it can sometimes present with symptoms that significantly impact the patient's quality of life. Diagnosis is usually straightforward based on physical examination.

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Diverticula of the jejunum is a rare but real disease with various manifestations. The diagnosis is often missed due to a lack of awareness, leading to delays and added complications, and consequently increased morbidity and mortality. Management remains controversial, ranging from a conservative approach that recommends rest, analgesics with close monitoring even for mildly complicated cases, to an aggressive approach justified by the increased risk of complications.

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Background: Atrial fibrillation (AF) is the most frequently encountered sustained arrhythmia worldwide. This supraventricular rhythm disorder is precipitated by advanced age, valvular heart disease, hypertension, heart failure, congenital heart defects, and others. However, the role of anabolic steroids (ASs) abuse in precipitating AF remains insufficiently researched and largely underreported, despite their known cardiovascular risks.

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Superior mesentery artery (SMA)-like syndrome is an increasingly used term to describe vascular compression of the third duodenal portion between structures other than the superior mesenteric artery and aorta. Although rare, this clinical condition is as serious as true SMA syndrome and requires similar management. However, the diagnostic criteria are not well established yet and require a case-by-case analysis, including a review of various clinical symptoms, especially evolving ones, as well as radiological imaging and effectiveness of conservative therapeutic manoeuvres.

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Introduction: Pheochromocytoma is a rare neuroendocrine tumor that arises from chromaffin cells in the adrenal medulla, with an incidence of 2-8 cases per million adults.

Case Presentation: This case study presents the case of a 39-year-old male patient who experienced recurrent headaches, palpitations, and hypertension, ultimately diagnosed with malignant pheochromocytoma after imaging revealed a large adrenal mass with vascular invasion and metastasis.

Discussion: Despite the rarity of malignant pheochromocytomas, they present significant clinical challenges.

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Article Synopsis
  • A 46-year-old woman with chronic kidney issues and kidney stones was diagnosed with primary hyperoxaluria type 1 (PH1) through a bone marrow biopsy.
  • Genetic testing revealed a specific mutation (p.Ile244Thr) in the AGXT gene, which is linked to the disorder.
  • The paper emphasizes the need for early diagnosis of kidney stone issues, especially in families with a history of the condition, to avoid severe kidney damage and systemic complications.
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