25 results match your criteria: "Ibn Rochd University Hospital of Casablanca[Affiliation]"

Glioblastoma Vaccines as Promising Immune-Therapeutics: Challenges and Current Status.

Vaccines (Basel)

June 2024

Laboratory of Biomedical and Translational Research, Faculty of Medicine, Pharmacy and Dental Medicine of Fez, Sidi Mohamed Ben Abdellah University, Fez 30070, Morocco.

Article Synopsis
  • Glioblastoma (GBM) is a very common and aggressive brain tumor, with standard treatments like surgery and chemotherapy not significantly improving patient outcomes.
  • *Current research is focusing on immunotherapy methods such as vaccines and T-cell therapies, which are showing encouraging results in trials.
  • *The review discusses the challenges of immunotherapy, identifies key biomarkers as potential therapeutic targets, and suggests strategies to enhance the effectiveness of treatments for GBM.
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Introduction: few studies have examined the factors influencing fertility differentials and the variation in their effects in countries with different socioeconomic and cultural backgrounds and different fertility transition paces. To address this gap, our study sought to first identify the factors that influenced fertility differentials in Morocco and Burundi during their fertility transition periods, and then to compare the effects of these factors between the two countries.

Methods: using data from the 2003-4 Morocco and 2010 Burundi Demographic and Health Surveys, bivariable and multivariable Poisson regression analyses offset by the natural logarithm of the women´s age were performed to identify the socioeconomic and cultural factors that influenced fertility differentials in Morocco and Burundi during their fertility transition.

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Article Synopsis
  • Micropulse transscleral cyclophotocoagulation (TSCPC) is being evaluated for its safety and effectiveness in treating refractory glaucoma in a study involving 39 eyes from 31 patients.
  • The procedure showed significant improvement, with intraocular pressure (IOP) reducing from an average of 42.3 mmHg pre-operation to 16.9 mmHg nine months post-operation, resulting in a reduction of nearly 50%.
  • Most patients experienced a decrease in the number of glaucoma medications needed, with a success rate of 60.5% in managing their condition.
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Background: Propranolol is the first-line treatment for infantile hemangiomas (IH). Cases of propranolol-resistant infantile hemangiomas are rarely reported. The purpose of our study was to investigate the predictive factors for poor response to propranolol.

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Introduction: According to the World Health Organization (WHO), disability is a public health problem that can be difficult to manage medically and financially. Disability can either be innate or develop after resuscitation. Therefore, the decision regarding whether to resuscitate a patient or not raises certain ethical questions, especially in the context of a Muslim country such as Morocco.

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Healthy adnexal torsion in pregnancy: A case report.

Int J Surg Case Rep

November 2022

Department of Gynecology - Obstetrics, Ibn Rochd University Hospital of Casablanca, Faculty of Medicine and Pharmacy of Casablanca, Hassan 2 University, Casablanca, Morocco.

• Adnexal torsion during pregnancy is a rare surgical emergency. • The diagnosis of certainty of adnexal torsion can only be made intraoperatively. • In the absence of any contraindication, laparoscopy should be the preferred approach.

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Risk factors for breast cancer in women: an update review.

Med Oncol

September 2022

Molecular Engineering, Biotechnology and Innovation Team, Geo-Bio -Environment Engineering and Innovation Laboratory, Polydisciplinary Faculty of Taroudant, IBN ZOHR University, Hay El Mohammadi (Lastah) B.P: 271, 83000, Taroudannt City, Morocco.

Article Synopsis
  • - Breast cancer is the most complex cancer and leading cause of death among women globally, according to the World Health Organization in 2021.
  • - Recent research highlights key risk factors for breast cancer, including age, family history, obesity, oral contraceptive use, menopausal status, smoking, alcohol intake, lifestyle choices, and genetics based on a compilation of 15 studies involving over 1.25 million participants.
  • - The establishment of a prevention program, supported by scientific evidence, could potentially save millions of lives, but more studies are necessary to confirm these findings and improve preventive practices.
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Background: Very little is known about factors influencing adolescent childbearing despite an upward trend in adolescent childbearing prevalence in Burundi, and its perceived implications on the rapid population growth and ill-health of young mothers and their babies. To adress this gap, this study aimed to examine the prevalence, trends and determinants of adolescent childbearing in Burundi.

Methods: Secondary analyses of the 1987, 2010 and 2016-17 Burundi Demographic and Health Surveys (BDHS) data were conducted using STATA.

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Primary clear cell adenocarcinoma of the vagina not associated with diethylstilbestrol: A case report.

Int J Surg Case Rep

September 2022

Mohamed VI Cancer Treatment Center, Ibn Rochd University Hospital of Casablanca, Faculty of Medicine and Pharmacy of Casablanca, Hassan II University, Casablanca, Morocco.

Primary vaginal cancers are rare and clear cell adenocarcinoma is a malignant tumor that is all the more rare when the woman has not been exposed in utero to synthetic diethylstilboestrol (DES). We report the case of a 60-year-old woman with a history of balanced essential hypertension and partial mastectomy for neoplasia, who presented with a recurrent left inguinal adenopathy. Clinical examination revealed a 3 cm bulging lesion of the anterior vaginal wall in the lower third with indurated left inguinal adenopathy.

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Cerebral fat embolism is a rare and potentially fatal condition that may occur following a long bone fracture. Its characterized by respiratory, neurological, and mucocutaneous signs. Isolated severe brain syndrome remains exceptional.

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Recurrent palpebral herpes complicated by preseptal cellulitis in a child.

J Fr Ophtalmol

September 2021

Hassan II University of Casablanca, Department of pediatric ophtalmology, Ibn Rochd University Hospital of Casablanca, 1, rue des Hôpitaux, Casablanca, Morocco.

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Acute spontaneous hematoma of the corpus callosum in a COVID-19 patient: a case report.

Pan Afr Med J

June 2021

Department of Nephrology, Ibn Rochd University Hospital of Casablanca, Hassan II University, Casablanca, Morocco.

Neurovascular involvement is a frequent occurring reported in COVID-19 patients. However, spontaneous hematomas of the corpus callosum are exceptionally seen. The authors of this article aim to report an unusual case of corpus callosum hematoma in a COVID-19 patient and discuss potential etiologies and mechanisms responsible for intracranial hemorrhage.

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Impact of pregnancy on papillary thyroid carcinoma prognosis.

Pan Afr Med J

June 2021

Endocrinology, Diabetology and Metabolic Disease Department, Ibn Rochd University Hospital of Casablanca, Casablanca, Morocco.

Introduction: thyroid carcinoma is more frequent in women of reproductive age. It can affect both fertility and the course of pregnancy. The aim of the study was to investigate the influence of pregnancy as a factor of recurrence or progression, on the prognosis of thyroid carcinoma.

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COVID-19: Patient care after discharge from the Intensive Care Unit.

Int J Clin Pract

September 2021

Pneumology Department, 20 Août Hospital, Ibn Rochd University Hospital of Casablanca, Faculty of Medicine and Pharmacy-University Hassan II, Casablanca, Morocco.

Introduction: The Ibn Rochd CHU is a tertiary care structure that provides care for the most severe cases of COVID-19 requiring hospitalisation in intensive care. The objective of study is to describe the complementary medical and psychological care of patients with COVID-19 in the endocrinology department after a stay in intensive care.

Patients And Methods: This is a descriptive observational study of patients transferred from the intensive care unit to the endocrinology service following a COVID-19 infection during the period from 17 April 2020 to May 26, 2020.

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Introduction: metabolic steatopathy or non-alcoholic fatty liver disease (NAFLD) is frequently associated with type 2 diabetes mellitus (T2DM) with an increased risk of progression to advanced fibrosis. The purpose of our study was to determine the interest of hepatic steatosis index (HSI) in the detection of hepatic steatosis in patients with type 2 diabetes in order to establish an appropriate screening program of this disease in our population.

Methods: cross-sectional study involving 281 type 2 diabetics hospitalized in the Department of Endocrinology in collaboration with the Hepato-gastroenterology Department at the University Hospital Ibn Rochd Casablanca between January 2018 and June 2018.

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Introduction And Importance: Colorectal cancer is a major global health problem. In 5% of cases, a genetic predisposition to cancer's syndrome is the etiology, such as Lynch syndrome. The population prevalence of Lynch syndrome has been estimated at 1/440.

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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread across the globe, leading to the declaration of a pandemic. While most present mild symptoms, it appears as though nearly 20% of confirmed patients develop significant complications. At this time of uncertainty, we are struggling to provide appropriate care to hematological cancer patients.

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Coronavirus disease-19 (COVID-19) associated with acute pancreatitis: case report.

Pan Afr Med J

February 2021

Department of Anesthesiology and Intensive Care, Ibn Rochd University Hospital of Casablanca, Hassan II University, Casablanca, Morocco.

The SARS-CoV-2 primarily attacks the respiratory system and the most common symptoms include cough, shortness of breath, and fever. However, its tropism for the digestive system has been demonstrated and its clinical digestive manifestations are increasingly recognized. Nevertheless, little attention has been paid to pancreatic lesions included in SARS-CoV-2 infection.

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Retinoblastoma is the most common malignant tumor of the eye in children (incidence:1/15,000 to 1/20,000 births), with a sex ratio of 1,5/1. Retinoblastoma, in its inherited form, is a disease caused by a syndrome of genetic predisposition to cancer. The RB1 gene, a tumor suppressor gene, is localized at 13q14.

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COVID-19 and fortuitous discovery of chronic lymphocytic leukemia: biological findings and therapeutic challenges.

Pan Afr Med J

November 2020

Department of Anesthesiology and Intensive Care, Ibn Rochd University Hospital of Casablanca, Hassan II University, Casablanca, Morocco.

With the major spread of SARS-COV-2 around the world, its association with various pathologies has been reported. However, hemopathy has rarely been revealed during a coronavirus infection. The authors of this article aim to emphasize the diagnostic and therapeutic challenges faced while treating COVID/hemopathy patients.

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Associated pediatric neuromyelitis optica and dermatomyositis: A case report.

Rev Neurol (Paris)

April 2020

Hassan II University of Casablanca, Pediatric Rheumatology department, Pediatrics 5, Harouchi Children's Hospital, Casablanca, Morocco.

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Article Synopsis
  • - The study investigates the role of endogenous vascular endothelial growth factor (EG-VEGF) in colorectal cancer (CRC) and its link to metastatic peritoneal carcinomatosis (PC), highlighting that high levels of circulating EG-VEGF are associated with advanced cancer stages.
  • - Increased circulating levels of EG-VEGF were found in metastatic PC patients compared to those with CRC and healthy controls, and local EG-VEGF expression was linked to higher tumor and nodal stages in CRC.
  • - The research suggests that the EG-VEGF and its receptors could play a key role in CRC's progression to PC and propose that circulating EG-VEGF might serve as a useful prognostic marker for CRC patients. *
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Pulmonary hypertension: prevalence and risk factors.

Int J Cardiol Heart Vasc

June 2016

Department of Nephrology, Dialysis and Renal Transplantation, Ibn Rochd University Hospital of Casablanca, 1, Quartier des Hôpitaux, Casablanca 20100, Morocco.

Article Synopsis
  • Pulmonary arterial hypertension (PAH) is prevalent in hemodialysis patients, with 16.22% of the studied group showing elevated pressures.
  • The study included 111 patients, finding that the average pulmonary artery pressure was 45 mm Hg, with a small percentage classified as having mild to severe PAH.
  • Key risk factors linked to PAH were longer hemodialysis duration and specific heart conditions like valvular calcification and regurgitation.
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T-acute lymphoblastic leukemia (T-ALL) represents 25 % of cases of acute lymphoblastic leukemia (ALL) in adults. The clinical presentation is dominated by a elevated number of white blood cells and in immunophenotype the lymphoblasts are generally Tdt positive and variably express CD1a, CD2, CD3, CD4, CD5, CD7, and CD8. NK/T non Hodgkin lymphoma is presented as a single lesion often ulcerated with torpid evolution affecting the nasal cavity, nasopharynx and/or palate.

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