4 results match your criteria: "IRMAR Mathematics Research Institute of Rennes[Affiliation]"
Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer.
Cell Mol Life Sci
May 2022
EA 7501 GICC, Université de Tours, Tours, France.
Background And Aims: Recent evidences highlight a role of the mitochondria calcium homeostasis in the development of colorectal cancer (CRC). To overcome treatment resistance, we aimed to evaluate the role of the mitochondrial sodium-calcium-lithium exchanger (NCLX) and its targeting in CRC. We also identified curcumin as a new inhibitor of NCLX.
View Article and Find Full Text PDFMid-infrared spectroscopy of serum, a promising non-invasive method to assess prognosis in patients with ascites and cirrhosis.
PLoS One
October 2017
IRMAR Mathematics Research Institute of Rennes, UMR-CNRS 6625, Rennes, France.
Background & Aims: Prognostic tests are critical in the management of patients with cirrhosis and ascites. Biological tests or scores perform poorly in that situation. Mid-infrared fibre evanescent wave spectroscopy (MIR-FEWS) which allows for global serum metabolic profiling may provide more relevant information by measuring a wider range of metabolic parameters in serum.
View Article and Find Full Text PDFMid-infrared fibre evanescent wave spectroscopy of serum allows fingerprinting of the hepatic metabolic status in mice.
Analyst
October 2016
INSERM UMR 991, F-35033 Rennes, France. and University of Rennes 1, 35043, Rennes, France.
Article Synopsis
- Non-alcoholic fatty liver disease happens when too much fat builds up in the liver and is linked to problems like obesity and diabetes.
- The study aimed to see if a special method using light (called mid-infrared fibre evanescent wave spectroscopy) can help check the liver's health without causing much harm.
- Results showed that this method can find different levels of fat in the liver based on blood samples, helping doctors understand how the liver is doing in patients with this disease.
A novel method for a fast diagnosis of septic arthritis using mid infrared and deported spectroscopy.
Joint Bone Spine
May 2016
INSERM UMR 991, 35033 Rennes, France; University of Rennes 1, 35043 Rennes, France.
Objective: To assess the ability of mid infrared deported spectroscopy to discriminate synovial fluids samples of septic arthritis patients from other causes of joint effusion.
Methods: Synovial fluids obtained from patients with clinically suspected arthritis were collected, analysed and classified according to standard diagnostic procedures as septic or non-septic. A spectroscopic analysis on synovial fluid samples was then performed using a coiled optical fiber made with chalcogenide glass.