5 results match your criteria: "IRCCS S.Luca Hospital[Affiliation]"

Sympathetic nervous system and hypertension: New evidences.

Auton Neurosci

March 2022

Clinica Medica, S. Gerardo Hospital, University Milano Bicocca, Monza, Italy.

Evidences collected in the past few years have strengthened the concept that the sympathetic nervous system plays a primary role in the development and progression of the hypertensive state, starting from the early stage, and in the hypertension-related cardiovascular diseases. Several pathophysiological mechanisms are involved. Among them the genetic background, the immune system in conjunction with sympathetic activation.

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Introduction: Serum uric acid (SUA) has been depicted as a contributory causal factor in metabolic syndrome (MS), which in turn, portends unfavourable prognosis.

Aim: We assessed the prognostic role of SUA in patients with and without MS.

Methods: We used data from the multicentre Uric Acid Right for Heart Health study and considered cardiovascular mortality (CVM) as death due to fatal myocardial infarction, stroke, sudden cardiac death, or heart failure.

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Article Synopsis
  • The study investigates the impact of short-term blood pressure variability (BPV) on mortality and cardiovascular events in haemodialysis patients, an area previously unexplored.
  • It involved 227 patients monitored continuously for 44 hours, analyzing various BPV metrics like standard deviation and average real variability over about 30 months.
  • Results showed that higher short-term BPV correlated with increased risks of all-cause death and cardiovascular issues, highlighting the importance of BPV monitoring in this patient population.
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Blood pressure variability is increasing from the first to the second day of the interdialytic interval in hemodialysis patients.

J Hypertens

December 2017

aTherapeutiki Hemodialysis Unit bDepartment of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki cPieria Hemodialysis Unit, Katerini dHemodialysis Unit, Achillopouleion General Hospital, Volos eSection of Nephrology and Hypertension, 1st Department of Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece fDepartment of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPAZ and CIBER in Epidemiology and Public Health (CIBERESP), Madrid, Spain gDepartment of Cardiovascular, Neural and Metabolic Sciences, IRCCS S. Luca Hospital, Istituto Auxologico Italiano hDepartment of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.

Objectives: Patients with end-stage renal-disease under hemodialysis have increased cardiovascular risk and experience severe blood pressure (BP) fluctuations during the dialysis session and the subsequent interdialytic period. BP variability (BPV) may be an additional risk factor for cardiovascular events and preliminary data suggest increased BPV with advancing stages of chronic kidney disease. This is the first study to examine BPV during the whole intradialytic and interdialytic period in hemodialysis patients with ambulatory BP monitoring.

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Markers of activation of coagulation and fibrinolysis in patients with Cushing's syndrome.

J Endocrinol Invest

March 2000

2nd Chair of Endocrinology, University of Milan, IRCCS S. Luca Hospital, Italian Auxologic Center.

Patients with active Cushing's syndrome have an increased thrombotic tendency. We chose to reassess the mechanism underlying the thrombophilic state associated with this clinical condition using sensitive markers of coagulation and fibrinolysis activation in 17 patients with active disease. The results were compared with those obtained in 12 Cushing's patients successfully treated by surgery and in 20 normal individuals.

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