Aurora kinase A expression in pleomorphic adenoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma of salivary glands: an immunohistochemical study.

Background: Aurora kinase A (AurkA) plays a vital role in mitosis and is therefore critical in tumors development and progression. There are a few studies on AurkA expression in salivary gland tumors. The aim of the present study was to evaluate the expression pattern of AurkA in the most common benign and malignant salivary gland tumors by immunohistochemistry.

Revamping field practicum: insights for future health services management professionals.

Background: The effectiveness of Health Services Management curricula relies heavily on practical experiences that reflect the evolving needs of the healthcare sector. This study focuses on revising Field Practicum 4 for undergraduate students to better prepare them for leadership roles in healthcare.

Methods: This qualitative and cross-sectional case study was conducted during the 2022-2023 academic year at Zabol University of Medical Sciences.

Is the convergence insufficiency symptom survey applicable to elderly individuals?

Background: The psychometric properties of the Convergence Insufficiency Symptom Survey (CISS) have been previously determined across the younger adult population. This study investigated the psychometric properties of the CISS in presbyopic adults via classical and Rasch analysis.

Methods: A total of 100 presbyopic individuals (40-60 years) were selected with far and near acuity of 20/20 with their habitual spectacles; 50 had convergence insufficiency and 50 had normal binocular vision.

Mental health literacy of reproductive age women: a qualitative study.

Background: Women's reproductive years are a time of increased vulnerability to mental health problems. However, only a small proportion of women seek help, and seems that poor mental health literacy is a major obstacle in this regard. This study aimed to elucidate the concept and provide a better understanding of the main dimensions of mental health literacy in women of reproductive age.

Exploring barriers to accessing health care services by young women in rural settings: a qualitative study in Australia, Canada, and Sweden.

Background: The aim of this study is to explore young rural women's perceived barriers in accessing healthcare services with a focus on the interrelation between three marginalization criteria: age (youth), gender (female), and place of residence (rural areas) in Australia, Canada, and Sweden.

Methods: Using a qualitative interpretive approach, we conducted semi-structured in-depth interviews with 31 young women aged 18 to 24 in selected rural communities. Data collection took place from May 2019 to January 2021, and the qualitative data were analyzed using NVivo software.

A multi-stage weakly supervised design for spheroid segmentation to explore mesenchymal stem cell differentiation dynamics.

Unlabelled: There is a growing interest in utilizing 3D culture models for stem cell and cancer cell research due to their closer resemblance to in vivo environments. In this study, human mesenchymal stem cells (MSCs) were cultured using adipocytes and osteocytes as differentiative mediums on varying concentrations of chitosan substrate. Light microscopy was employed to capture cell images from the first day to the 21st day of differentiation.

Mitigating soil compaction and enhancing corn (Zea mays L.) growth through biological and non-biological amendments.

Soil compaction is a pressing issue in agriculture that significantly hinders plant growth and soil health, necessitating effective strategies for mitigation. This study examined the effects of sugarcane bagasse, both in its raw form and as biochar, along with biological activators (Bacillus simplex UTT1 and Phanerochaete chrysosporium) on soil characteristics and corn (Zea mays L.) plant biomass in a compacted soil.

Agronomic characteristics, mineral nutrient content, antioxidant capacity, biochemical composition, and fatty acid profile of Iranian pistachio (Pistacia vera L.) cultivars.

Background: Pistachio (Pistacia vera L.) nuts are among the most popular nuts. The pistachio cultivars are tolerant to both drought and salinity, which is why they are extensively grown in the arid, saline, and hot regions of the Middle East, Mediterranean countries, and the United States.

Investigating the effect of ceramic fiber on the mechanical properties of glassphalt.

Glassphalt suffers from performance defects, especially against moisture damage and fatigue cracking. In this research, the performance of glassphalt modified with CF has been evaluated against moisture damage, fatigue cracking and rutting. Based on this, Modified Lottman, Wilhelmy Plate (WP), Indirect Tensile Stiffness Modulus (ITSM), Indirect Tensile Fatigue (ITF), and Repeated Load Axial (RLA) tests have been performed on glassphalt modified with CF.

Comparing the effects of Mycozin and Clotrimazole 1% creams on vaginal candidiasis: a triple-blinded randomized controlled trial.

Clotrimazole 1% and Mycozin vaginal cream have been reported to be effective in relieving the symptoms of vulvovaginitis caused by Candida. The resistance to azole compounds, and the side effects of chemical drugs have been reported following azole therapy. It was hypothesized that Mycozin is at least as effective as Clotrimazole in treating vaginal candidiasis.

Designing a terahertz optical sensor based on helically twisted photonic crystal fiber for toxic gas sensing.

A novel helically twisted photonic crystal fiber (PCF) is designed and proposed for sensing toxic gases with refractive indices ranging from 1.00 to 1.08.

A sustainable and green method for controlling acidic corrosion on mild steel using leaves of Araucaria heterophylla.

There are several studies that announce the inhibitory behavior of this sort of substance to strengthen the shield of metals, which is one of the positive benefits of green inhibitors. In the current investigation, Araucaria heterophylla studied as a green corrosion inhibitor to avert the mild steel during the acidic cleaning. The examination of this plant's ability to control corrosion at different concentrations in the acidic solution used certain expert measures.

Determination of genetic diversity in persimmon accessions using morphological and inter simple sequence repeat markers.

Background: Persimmon (Diospyros kaki L.) belongs to the Ebenaceae family, which includes six genera and about 400 species. This study evaluated the genetic diversity of 100 persimmon accessions from Hatay province, Türkiye using 42 morphological and pomological traits, along with inter simple sequence repeat (ISSR) markers and multivariate analysis.

CRISPR challenges in clinical developments.

CRISPR-Cas (clustered regularly interspaced short palindromic repeats and associated proteins) is a novel genome editing technology with potential applications in treating diseases. Currently, its use in humans is restricted to clinical trials, although its growth rate is significant, and some have received initial FDA approval. It is crucial to examine and address the challenges for this technology to be implemented in clinical settings.

Characterization and application of polysaccharides produced by Pseudomonas atacamensis M7D1 for chromium (III) removal from tannery effluent.

The wastewater from various industries contaminated with heavy metals poses significant environmental challenges. Biosorption has emerged as a widely used method for removing heavy metals from industrial wastewater. Pseudomonas atacamensis M7D1 is known to produce polysaccharides, but the potential of its polysaccharides as an adsorbent for heavy metal removal still needs to be explored.

Vanillin and IGF1-loaded dual-layer multifunctional wound dressing with micro-nanofibrous structure for full-thickness wound healing acceleration.

Multifunctional dual-layer wound dressings hold significant promise for comprehensive full-thickness wound management by closely mimicking the native skin structure and features. Herein, we employed an innovative approach utilizing electrospinning techniques to develop a dual-layer dressing comprising a microfibrous Ecoflex®-Vanillin (Ex-Vnil) top layer (TL) and a nanofibrous Soluplus®-Insulin-like growth factor-1 (Sol-IGF1) bottom layer (BL). The tensile properties of dual-layer wound dressings were within the standard range for use in skin tissue regeneration.

Optimization of environmental and energy performance of egg production using data envelopment analysis (DEA) and life cycle assessment (LCA).

Intensive farming systems can present different environmental concerns. Among the many animal products, eggs are consumed globally as a cheap, valuable source of protein. Iran is among the top 10 egg producing countries in the world.

A mechanistic insight into whey protein isolate (WPI) fibrillation driven by divalent cations.

Protein fibrillation complex mechanisms led to an emerging trend in research for years. The mechanisms behind whey protein isolate (WPI) fibrillation driven by divalent cations remained still a matter of speculation. All cations (Ca, Fe, Mg, and Zn) enhanced the microenvironment polarity through π-π stacking, and the amide I and II shifts confirmed the fibrillation.

Implementing active learning approach to promote motivation, reduce anxiety, and shape positive attitudes: A case study of EFL learners.

Active Learning (AL) represents a transformative instructional approach that departs from traditional methods by immersing students in experiential learning activities such as problem-solving, discussions, role-plays, interactive engagement, and case studies. Despite its widely recognized potential, the effects of AL on psycho-affective constructs in English as a Foreign Language (EFL) contexts remain underexplored. Hence, this study explored the impact of AL on EFL learners' motivation, attitudes, and anxiety in Iran.

Evaluation of anti-Pertussis antibody levels in Iranian infants and children: Is it time to include booster acellular Pertussis Vaccines in the immunization schedule?

Introduction: The prevalence of anti-pertussis antibodies among infants and children in Iran has not been thoroughly investigated. Given that recommendations for booster vaccines are based on national disease epidemiology, we aimed to evaluate the seroprevalence of pertussis antibodies among infants and children in an Iranian referral hospital.

Materials And Methods: A total of 1012 infants and children were included in the study.

Using direct method to estimate calcium digestibility of barley and soybean meal in quail chicks.

The availability of calcium (Ca) in poultry diets is influenced by various factors, such as the feed ingredients used. This study assessed the apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of Ca in barley and soybean meal (SBM) in young quail chicks using a direct method. Three diets were formulated, including a Ca-free basal diet to evaluate ileal endogenous calcium losses (IECaL), and two diets with barley or SBM as the sole Ca sources.

Evaluation of sectional anatomic, micro-computed tomographic, and magnetic resonance imaging features of the thorax in Syrian hamsters (Mesocricetus auratus).

Clinically, the rodent thorax is important because of the variety of problems that may affect the heart, lungs, and other thoracic structures. Syrian hamsters are the most common pet and experimental hamster species. Sectional imaging of small mammals is widely increasing in use for clinical and research settings; however, no reports on the thoracic sectional imaging anatomy in this species have been made.

Expression level of miR-548aa in tissue samples of patients with colorectal cancer.

Background: The pathogenesis of colorectal cancer (CRC) is influenced by various risk factors, and genetic alterations in progression of colon polyps. The expression patterns of microRNA-548 (miR-548) in colorectal tissues have been sufficiently characterized. The aim of this study is to clarify the role of miR-548aa in tumorigenesis, gene targeting, predictive value and its expression levels in tumoral versus adjacent marginal tissues in CRC patients.

A Protocol for Detecting DNA Methylation Changes at CpG Sites of Stemness-Related Genes in Aging Stem Cells.

Aging adversely affects the self-renewal and differentiation capabilities of stem cells, which impairs tissue regeneration as well as the homeostasis. Epigenetic mechanisms, specifically DNA methylation, play a key role in the maintenance of pluripotency in stem cells and regulation of pluripotency-related gene expression. Age-related modifications in methylation patterns could influence the expression of genes critical for stem cell potency maintenance, including transcription factors Nanog and Sox2.

Behavioral and acaricidal effects of the chlorfenapyr and acequinocyl on the predatory mites, Neoseiulus californicus and Phytoseiulus persimilis (Acari: Phytoseiidae).

The two-spotted spider mite, Tetranychus urticae Koch (Acari: Tetranychidae), is a major pest of various plants with a worldwide distribution. Extensive use of chemical pesticides has led to the development of resistance in this pest, making biological control agents a viable alternative for its management. The predatory mites, Neoseiulus californicus (McGregor) and Phytoseiulus persimilis Athias-Henriot (Acari: Phytoseiidae) are the most important predators of the two-spotted spider mites.