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Outcomes after stroke thrombolysis according to prior antiplatelet use.

Int J Stroke

February 2015

Department of Neurology and Stroke Centre, Bichat University Hospital, Paris, France; Laboratory of Vascular Translational Science, INSERM 1148 and Paris-Diderot University, Paris, France.

Background: Thirty percent of ischemic stroke (IS) patients suffering from acute stroke are under antiplatelet therapy.

Aims: We evaluated whether prior antiplatelet use before intravenous (IV), intra-arterial (IA) or combined IV/IA therapy may be associated with worse outcomes and an increased intracerebral hemorrhage (ICH) risk after reperfusion therapies.

Methods: We analyzed data from our patient registry (n = 874) and conducted a systematic review of previous observational studies.

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