1 results match your criteria: "INO (National Optics Institute)[Affiliation]"
Effect of liposomal confinement on photochemical properties of photosensitizers with varying hydrophilicity.
J Biomed Opt
January 2009
INO (National Optics Institute), Department of Biophotonics, 2740 Einstein Street, Quebec G1P 4S4, Canada.
Article Synopsis
- The study investigates how the hydrophilic or hydrophobic properties of photosensitizers (PSs) influence their localization and phototoxic effects in a cellular model using liposomes.
- Three different PSs with varying hydrophilicity were analyzed for their absorbance and fluorescence properties both in bulk solution and when confined within liposomes, revealing distinct localization patterns.
- The findings highlight that the differences in the aggregation state of PSs within liposomes are influenced by their hydrophilicity, which could lead to better optimization of photodynamic therapy drugs.