856,201 results match your criteria: "IN; and Indiana University School of Medicine Department of Emergency Medicine P.V.[Affiliation]"

Intraoperative neurophysiological monitoring (IONM) has achieved popularity because it facilitates monitoring of the functional integrity of neural structures under general anesthesia. It aids in the early detection of injury and minimizes postoperative neurologic deficit or neurologic morbidity from surgical manipulations of various neurologic structures. The patient mentioned in this case report presented with lower limb radiculopathy and was diagnosed with diastematomyelia Type II, and she was planned for surgical intervention under general anesthesia.

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Medial meniscus root tears (MMRTs) are serious injuries that disrupt knee biomechanics, often accelerating cartilage degeneration and osteoarthritis when left untreated. These injuries are increasingly recognized as a major cause of knee pain and functional limitations, particularly among middle-aged and older adults. This systematic review and meta-analysis aimed to evaluate the outcomes of conservative management compared to surgical intervention for MMRT, focusing on pain relief, functional recovery, and the progression of osteoarthritis.

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Penetrating thoracic injuries, especially those affecting cardiac structures, are rare but can be life-threatening, requiring urgent medical care. Right atrium injuries pose significant risks, including rapid blood loss, cardiac tamponade, hemodynamic instability, and, subsequently, potential death. We report the case of a 24-year-old male patient with stab wounds leading to a right-sided chest penetration three hours prior to presentation.

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Persistent anterolateral ankle pain is a debilitating condition often associated with soft tissue impingement following inversion injuries. It can lead to significant limitations in daily activities and overall quality of life, particularly in individuals with chronic ankle instability. This systematic review examines the efficacy and safety of minimally invasive arthroscopic decompression techniques in managing anterolateral ankle impingement syndrome.

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Terson Syndrome in Two Infants: Case Report and Literature Review.

Cureus

December 2024

Department of Ophthalmology, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, SAU.

Article Synopsis
  • The report discusses two infants in Saudi Arabia diagnosed with Terson syndrome following traumatic head injuries.
  • Both infants underwent pars plana vitrectomy (PPV) in an attempt to improve their vision.
  • Unfortunately, both cases resulted in poor visual outcomes due to complications such as macular scars and retinal detachment.
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Introduction: On-road tests are considered the gold standard for evaluating real-world driving skills. However, their reliability and validity remain inadequately established, particularly under varying legal and road conditions across countries.

Aim: This study investigates the discriminant validity of the closed-course version of the Standardized On-Road Assessment for Drivers (SOAD) in Japan.

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The aim of this systematic review and meta-analysis was to evaluate and compare the effectiveness of surgical fasciotomy and conservative management for chronic exertional compartment syndrome (CECS) concerning symptom relief, functional recovery, and patient satisfaction. A comprehensive search of PubMed, Scopus, Google Scholar, and Cochrane Library identified studies comparing surgical fasciotomy with conservative management for CECS. Four studies met the inclusion criteria, comprising both retrospective and prospective cohort designs.

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Article Synopsis
  • This review and meta-analysis evaluated the effectiveness of single-bundle (SB) vs. double-bundle (DB) techniques in ACL reconstruction, analyzing ten different studies to primarily assess knee stability and functional outcomes.
  • Results indicated no significant differences in knee stability (Lachman and pivot-shift tests) or patient-reported outcomes (IKDC and Lysholm scores) between SB and DB techniques, suggesting both are equally effective.
  • Moderate variability among the studies pointed to the need for more standardized research methods to confirm these findings across various patient groups.
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Osteochondritis dissecans is a rare condition characterized by the deterioration of a small area of bone and cartilage without infection. Its exact cause is unclear, though factors such as abnormal bone development, joint pressure, repetitive injuries, inadequate blood supply, and genetic links have been observed. In this case, a 27-year-old woman experienced chronic right knee pain following a twisting injury, which led to reduced mobility and mild pain.

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Novel carbon dots with dual Modulatory effects on the bone marrow and spleen as a potential therapeutic candidate for treating spinal cord injury.

Bioact Mater

March 2025

Tianjin Key Laboratory of Spine and Spinal Cord, International Science and Technology Cooperation Base of Spinal Cord Injury, Department of Orthopedics, International Chinese Musculoskeletal Research Society Collaborating Center for Spinal Cord Injury, Tianjin Medical University General Hospital, Tianjin, 300070, China.

Spinal cord injury triggers leukocyte mobilization from the peripheral circulation to the injury site, exacerbating spinal cord damage. Simultaneously, bone marrow hematopoietic stem cells (HSCs) and splenic leukocytes rapidly mobilize to replenish the depleted peripheral blood leukocyte pool. However, current treatments for spinal cord injuries overlook interventions targeting peripheral immune organs and tissues, highlighting the need to develop novel drugs capable of effectively regulating peripheral immunity and treating spinal cord injuries.

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Research progress on digestive disorders following traumatic brain injury.

Front Immunol

January 2025

Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.

Article Synopsis
  • Traumatic brain injury (TBI) is a significant global health issue, leading to digestive dysfunction that complicates recovery and health outcomes.
  • The mechanisms affecting digestion post-TBI include inflammation, the enteric nervous system, and hormonal changes, all of which can hinder neurologic recovery through the brain-gut axis.
  • The article explores the pathogenesis of digestive issues after TBI, aiming to enhance treatment strategies and the long-term prognosis for patients by improving digestive function through recent technological advancements.
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The rotator cuff, a vital group of tendons and muscles in the shoulder, is essential for stabilizing the joint and enabling a wide range of arm movements. Rotator cuff tears, common across all age groups, often cause significant pain and functional limitations. Rotator cuff repair surgery aims to alleviate pain, restore function, and improve quality of life.

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Blunt abdominal trauma causing intraperitoneal injury and/or bleeding can be life-threatening, requiring immediate intervention. Diagnosing these cases can be challenging, especially when pre-existing conditions are involved. Low-grade appendiceal mucinous neoplasm (LAMN) is a rare tumor of the appendix that can lead to pseudomyxoma peritonei.

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Purpose: This biomechanical study aimed to investigate the effectiveness of a hinged elbow orthosis in reducing passive valgus forces following medial ulnar collateral ligament (UCL) injuries of the elbow joint. The hypothesis tested was that a hinged elbow orthosis reduces these passive valgus forces.

Methods: Eight fresh frozen cadaveric elbow specimens were prepared and tested under three scenarios: intact ligaments, simulated UCL rupture and application of a hinged elbow brace after simulated UCL rupture.

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Background And Aims: Even though patient tolerance is critical to the success of noninvasive ventilation (NIV), research on using sedation to improve tolerance to NIV after traumatic chest injuries is limited. We hypothesized that dexmedetomidine would be superior to ketamine in terms of patient tolerance and lengthening the NIV sessions after blunt chest trauma.

Material And Methods: This randomized, double-blinded, placebo-controlled trial included 45 patients of both genders aged 18-60 who needed NIV after blunt chest trauma.

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Noggin Combined With Human Dental Pulp Stem Cells to Promote Skeletal Muscle Regeneration.

Stem Cells Int

December 2024

Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Shanghai Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, China.

Article Synopsis
  • Dental pulp stem cells (DPSCs) show promise for muscle injury repair, but their ability to differentiate into muscle cells is currently limited.
  • Treating DPSCs with Noggin, which inhibits bone morphogenetic protein (BMP) signals, enhances myogenic differentiation, increases myogenic markers, and generates satellite-like cells, improving muscle regeneration.
  • Implanting Noggin-treated DPSCs in a mouse model of muscle loss resulted in significant reductions in defect size and scar tissue, indicating that BMP/Smad signaling regulation by Noggin effectively promotes muscle repair.
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Musculoskeletal ultrasound (MSKUS) has emerged as a valuable diagnostic tool in the evaluation and management of lateral elbow pathologies. This imaging modality provides high-resolution, dynamic visualization of superficial soft tissue structures, making it particularly advantageous for assessing conditions such as lateral epicondylitis (tennis elbow), ligamentous injuries, radial tunnel syndrome, and other common disorders. This article reviews the utility of MSKUS for rehabilitation providers, focusing on its role in accurately identifying pathoanatomical changes, guiding treatment strategies, and monitoring therapeutic outcomes.

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Background: The United States military strives to prepare soldiers physically and mentally for war while preventing injury and attrition. Previous research has focused on physical injury risk factors but has not prospectively examined psychological risk factors.

Purpose: This study's purpose was to investigate whether self-efficacy is a risk factor for musculoskeletal injury in an initial military training environment and compare it to other known risk factors.

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Injuries are commonplace in the overhead athlete, with many occurring to the shoulder and elbow. The increasing prevalence of injuries to the shoulder and elbow has been discussed at length in recent years, with increased research focus being placed on arm care for rehabilitation and prevention strategies. Even though the pitching motion is well-established as a whole-body kinetic chain movement, most attention in rehabilitation and prevention efforts is often placed on the upper extremity.

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Vascular Injury of Penetrating Trauma of the Extremities.

Emerg Med Int

December 2024

Department of Emergency Medicine, Etimesgut Sehit Sait Ertürk Hospital, Ankara, Türkiye.

Physical examination and computed tomography angiography (CTA) are used for diagnosing arterial injury in extremity trauma. In recent years, CTA has been overused to obtain more objective data. Our study aimed to investigate the effect of using CTA for the management of patients with extremity penetrating injuries, specifically in cases where vascular injury was not detected during initial examination.

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Purpose: Trauma-associated coagulopathy has been considered to develop as a result of increased fibrinolysis due to massive bleeding, tissue damage and hypoperfusion. However, it has not been investigated whether hematoma may cause trauma-associated coagulopathy. Using experimental animal model, we analyzed the effects of hematoma formation on coagulation and fibrinolysis parameters.

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Article Synopsis
  • The study focused on elderly patients (65+) with fall-related injuries who were also infected with COVID-19, analyzing their hospital outcomes.
  • A total of 807 patients were reviewed, where 16% were tested for COVID-19, resulting in a 17% positivity rate among those tested, showcasing common comorbidities like hypertension and diabetes.
  • The findings highlighted significant complications such as respiratory failure and a 19% in-hospital mortality rate, suggesting that COVID-19 poses a severe risk for older adults with fall injuries.
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Introduction: The aim of this study was to assess the percentage of trauma patients admitted and receiving intervention, and to identify which of these interventions were performed by non-trauma specialists.

Methods: The authors conducted a retrospective chart review of all adult patients who presented to the trauma service between January 2019 and June 2019. Collected data included demographics, trauma activation level, total interventions performed, interventions performed by the trauma team, interventions performed by subspecialty teams, and isolated injuries requiring orthopedic, neurosurgical, or other specialized care.

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