140 results match your criteria: "IMPACT Institute[Affiliation]"

Psychological factors of emotional distress and cognition have an important role in the understanding and management of endometriosis; however, their temporal relationship with key pain variables is not fully understood. This exploratory study sought to establish the temporal relationship between psychological and pain-related factors in a 12-month prospective study of 208 Australian women with endometriosis. Participants, aged 18-50 years and living in Australia, were recruited via social media and completed baseline (May 2019) and 12-month follow-up (June 2020) surveys.

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Article Synopsis
  • Inflammatory bowel disease (IBD) is a long-term gastrointestinal condition where standard treatments may not suffice for all patients, especially those labeled as Patients at Risk of Suboptimal Outcomes (PARSO).
  • The study analyzed 760 PARSO and 208 control participants through two online surveys to investigate various biopsychosocial factors influencing IBD outcomes, including quality of life, stress, and fatigue.
  • Findings revealed that factors such as younger age, female sex, Crohn's disease, and higher disease activity levels are significantly linked to being categorized as PARSO, suggesting a need for personalized, multidisciplinary treatment approaches for better patient well-being.
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Serum levels of carnosine may be associated with the duration of MDD episodes.

J Affect Disord

January 2023

Institute of Clinical Medicine, University of Oslo, Oslo, Norway; R&D department, Division of Mental Health Services, Akershus University Hospital, Lørenskog, Norway; Department of Psychiatry, University of Helsinki, Helsinki, Finland.

Background: Major depressive disorder (MDD) is a recurrent disorder that incurs a high societal burden. However, the etiology of MDD remains unclear. The functioning of several systems associated with the etiopathogenesis of MDD, such as inflammatory and stress systems, is partially modulated by the dipeptide carnosine.

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Advocacy is instrumental to achieving significant policy change for vision. Global advocacy efforts over the past decades enabled recognition of vision as a major public health, human rights, and development issue. The United Nations General Assembly adopted its first-ever Resolution on vision: "Vision for Everyone-Accelerating Action to Achieve the Sustainable Development Goals (SDGs)" on 23 July 2021.

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Background: Mis/disinformation has reached an epidemic level with the COVID-19 virus and can be largely attributed to the growing digitalization of information and its rapid transmission via social media. Approximately 96% of Canadians and 80% of Americans report encountering COVID-19 dis/misinformation on at least one social media site/app. COVID-19 dis/misinformation promotes scepticism and a lack of confidence in COVID-19 interventions.

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Musculoskeletal Deficits and Cognitive Impairment: Epidemiological Evidence and Biological Mechanisms.

Curr Osteoporos Rep

October 2022

Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, 635 Barnhill Drive, MS5022A, Indianapolis, IN, 46202, USA.

Purpose Of Review: Cognitive impairment is associated with obesity, sarcopenia, and osteoporosis. However, no critical appraisal of the literature on the relationship between musculoskeletal deficits and cognitive impairment, focusing on the epidemiological evidence and biological mechanisms, has been published to date. Herein, we critically evaluate the literature published over the past 3 years, emphasizing interesting and important new findings, and provide an outline of future directions that will improve our understanding of the connections between the brain and the musculoskeletal system.

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This study explores the discourse of social entrepreneurs and their audiences in pitch situations. Adopting a practice perspective on social entrepreneurship, we videotaped 49 pitches by social entrepreneurs at five different events in two incubators in Germany and Switzerland. Our analysis of the start-ups' pitches and the audience's questions and comments as well as of interview data elucidates the nuances of social and business discourse that social entrepreneurs and their audiences draw upon.

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Background: Low bone density (BMD) and fractures commonly affect women with premature ovarian insufficiency (POI). However, bone microarchitecture and body composition data are lacking.

Objective: To assess and characterise musculoskeletal phenotype and effects of oestrogen replacement therapy (ERT) in women with POI.

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Trends and Predictors of Cardiac Rehabilitation Referral Following Percutaneous Coronary Intervention: A Prospective, Multi-Site Study of 41,739 Patients From the Victorian Cardiac Outcomes Registry (2017-2020).

Heart Lung Circ

September 2022

School of Public Health and Preventive Medicine, Monash University, Melbourne, Vic, Australia; Department of Cardiology, The Alfred Hospital, Melbourne, Vic, Australia; Department of Cardiology, Western Health, Melbourne, Vic, Australia; Centre for Research and Evaluation, Ambulance Victoria, Melbourne, Vic, Australia; Baker Heart and Diabetes Institute, Melbourne, Vic, Australia.

Background: Following percutaneous coronary intervention (PCI), outpatient cardiac rehabilitation (CR) is essential for secondary prevention. However uptake of CR is suboptimal, despite strong evidence demonstrating benefits. The aim of this study was to identify contemporary trends and predictors of CR referral of PCI patients in Victoria.

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Unlabelled: We describe the collection of cohorts together with the analysis plan for an update of the fracture risk prediction tool FRAX with respect to current and novel risk factors. The resource comprises 2,138,428 participants with a follow-up of approximately 20 million person-years and 116,117 documented incident major osteoporotic fractures.

Introduction: The availability of the fracture risk assessment tool FRAX® has substantially enhanced the targeting of treatment to those at high risk of fracture with FRAX now incorporated into more than 100 clinical osteoporosis guidelines worldwide.

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We aimed to examine associations between skeletal muscle deficits and indices of poor health. Cut-points for skeletal muscle deficits were derived using data from the Geelong Osteoporosis Study and definitions from the revised European Consensus on Definition and Diagnosis and the Foundation for the National Institutes of Health. Participants ( = 665; 323 women) aged 60-96 year had handgrip strength measured by dynamometry and appendicular lean mass by whole-body dual-energy X-ray absorptiometry.

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What works for whom when treating major depression with psychotherapy?

Aust N Z J Psychiatry

September 2022

Academic Department of Psychiatry, Kolling Institute, Northern Clinical School, Faculty of Medicine and Health, The University of Sydney, Saint Leonards, NSW, Australia.

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The Relationship Between Adverse Childhood Experiences and Alzheimer's Disease: A Systematic Review.

Front Aging Neurosci

May 2022

School of Medicine, IMPACT - Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, VIC, Australia.

Background: Alzheimer's disease is a global health concern, and with no present cure, prevention is critical. Exposure to adverse childhood experiences may increase the risk of developing Alzheimer's disease. This systematic review was conducted to synthesize the evidence on the associations between adverse childhood experiences (<18 years) and the risk of Alzheimer's disease in adulthood.

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Objectives: Effectively supporting the mental health of elite athletes and coaches requires validated tools that assess not only individual-level factors but organisational-level influences. The aim of this study was to develop a bespoke scale assessing perceived psychological safety within high-performance environments.

Methods: 337 elite athletes (=24.

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Contemporary myocardial infarction (MI) care and management has evolved dramatically since the 1950's; yet outpatient rehabilitation remains underutilized. Deepening our understanding of the origins and history of cardiac rehabilitation highlights a contemporary shift required for policy and practice related to secondary prevention of coronary disease in light of societal changes as well as medical, digital and surgical advancements. Contemporary "cardiac rehabilitation" began when bed rest and physical inactivity was recommended and commonplace for MI survivors.

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Objective: To rebut the claims made in an opinion piece by Anaf and colleagues regarding the recommendations for psychotherapy within the 2020 RANZCP Mood Disorders Clinical Practice Guidelines (CPG).

Conclusions: The CPG attaches importance to psychological interventions and recommends their administration as first-line in the treatment of depression. The concerns raised by Anaf and colleagues have no basis and are readily dismissed by referring to the guidelines.

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Changes in body composition in the year following critical illness: A case-control study.

J Crit Care

October 2022

Deakin University, IMPACT (Institute of Mental and Physical Health and Clinical Translation), Geelong, Australia; Barwon Health, Geelong, Australia; Australian and New Zealand Intensive Care Research Centre (ANZIC-RC) Department of Epidemiology and Preventive Medicine (DEPM), Monash University, Melbourne, Australia.

Purpose: To measure changes in dual x-ray absorptiometry (DXA) derived body composition in Intensive Care Unit (ICU) survivors in the year following discharge and compare to population controls.

Materials And Methods: Using prospective observational data changes in hip and spine DXA estimated lean and fat mass between ICU discharge and 1-year follow-up were calculated and compared with age-sex-height matched controls from the Geelong Osteoporosis Study via multivariable linear regression.

Results: Sixty-four participants were included, with median age 68.

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Article Synopsis
  • Fatigue in inflammatory bowel disease (IBD) is often not effectively managed, and while psychotherapy shows potential, current methods need enhancements due to varying results and high dropout rates.
  • This study explored factors influencing willingness to engage in psychotherapy for IBD-related fatigue, including mental health, IBD activity, pain, and beliefs about psychotherapy.
  • Results from a survey of 834 participants indicated that antidepressant use, pain levels, and self-worth beliefs are significant predictors of willingness to try psychotherapy, suggesting clinicians should focus on addressing patient expectations.
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There is accumulating evidence for the fundamental role of diet in the integrated care of disorders of gut-brain interaction. Food is a complex mixture of components with individual, synergistic, and antagonistic effects, compared with the relative purity of a pharmaceutical. Food is also an inherent part of individuals' daily lives, and food choice is strongly tied to food preferences, personal beliefs, cultural and religious practices, and economic status, which can influence its ability to function as a therapeutic intervention.

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Addressing high and stagnant physical inactivity rates remains a pervasive challenge for researchers, and a priority for health organisations, governments, and physical activity practitioners. Leaders are a prevailing feature of numerous physical activity contexts and can fundamentally influence people's physical activity behaviours and experiences. In line with this, fitness companies and organisations commonly claim that the leaders of their classes, groups, or sessions will motivate, inspire, and ensure exercisers achieve their goals.

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Background: This article describes the research activities undertaken to plan and design a self-compassion intervention for family carers of people living with dementia using a person-based and co-design approach. In providing this example, our aim is two-fold: to highlight the value of using qualitative research and co-design processes within intervention development; and to showcase systematic reporting of an intervention's early planning and design stages.

Methods: A person-based and co-design approach informed the planning and design of the self-compassion intervention.

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