Hybrid Plasmonic Symmetry-Protected Bound state in the Continuum Entering the Zeptomolar Biodetection Range.

Photonics bound states in the continuum (BICs) are peculiar localized states in the continuum of free-space waves, unaffected by far-field radiation loss. Although plasmonic nano-antennas squeeze the optical field to nanoscale volumes, engineering the emergence of quasi-BICs with plasmonic hotspots remains challenging. Here, the origin of symmetry-protected (SP) quasi-BICs in a 2D system of silver-filled dimers, quasi-embedded in a high-index dielectric waveguide, is investigated through the strong coupling between photonic and plasmonic modes.

Editorial for the Special Issue on MEMS and Microfluidic Devices for Analytical Chemistry and Biosensing.

The outbreak of the SARS-CoV-2 pandemic has made the general public aware of the breakthrough technologies which were developed in recent years for state-of-the-art biosensing, and terms such as clinical specificity and sensitivity are now widely understood [...

Behavioral Change Prediction from Physiological Signals Using Deep Learned Features.

Predicting change from multivariate time series has relevant applications ranging from the medical to engineering fields. Multisensory stimulation therapy in patients with dementia aims to change the patient's behavioral state. For example, patients who exhibit a baseline of agitation may be paced to change their behavioral state to relaxed.

Remaining Useful Life Prediction from 3D Scan Data with Genetically Optimized Convolutional Neural Networks.

In the current industrial landscape, increasingly pervaded by technological innovations, the adoption of optimized strategies for asset management is becoming a critical key success factor. Among the various strategies available, the "Prognostics and Health Management" strategy is able to support maintenance management decisions more accurately, through continuous monitoring of equipment health and "Remaining Useful Life" forecasting. In the present study, convolutional neural network-based deep neural network techniques are investigated for the remaining useful life prediction of a punch tool, whose degradation is caused by working surface deformations during the machining process.

Emerging oxidized and defective phases in low-dimensional CrCl.

Two-dimensional (2D) magnets such as chromium trihalides CrX (X = I, Br, Cl) represent a frontier for spintronics applications and, in particular, CrCl has attracted research interest due its relative stability under ambient conditions without rapid degradation, as opposed to CrI. Herein, mechanically exfoliated CrCl flakes are characterized at the atomic scale and the electronic structures of pristine, oxidized, and defective monolayer CrCl phases are investigated employing density functional theory (DFT) calculations, scanning tunneling spectroscopy (STS), core level X-ray photoemission spectroscopy (XPS), and valence band XPS and ultraviolet photoemission spectroscopy (UPS). As revealed by atomically resolved transmission electron microscopy (TEM) and energy dispersive X-ray (EDX) analysis, the CrCl flakes show spontaneous surface oxidation upon air exposure with an extrinsic long-range ordered oxidized O-CrCl structure and amorphous chromium oxide formation on the edges of the flakes.

Vision-Based Road Rage Detection Framework in Automotive Safety Applications.

Drivers' road rage is among the main causes of road accidents. Each year, it contributes to more deaths and injuries globally. In this context, it is important to implement systems that can supervise drivers by monitoring their level of concentration during the entire driving process.

A Reliable BioFET Immunosensor for Detection of p53 Tumour Suppressor in Physiological-Like Environment.

The concentration of wild-type tumour suppressor p53 in cells and blood has a clinical significance for early diagnosis of some types of cancer. We developed a disposable, label-free, field-effect transistor-based immunosensor (BioFET), able to detect p53 in physiological buffer solutions, over a wide concentration range. Microfabricated, high-purity gold electrodes were used as single-use extended gates (EG), which avoid direct interaction between the transistor gate and the biological solution.

Near-field enhancement in oxidized close gap aluminum dimers.

Aluminum bowtie nanoantennas represent a possibility to confine and enhance electromagnetic (EM) field at optical frequencies in subwavelength regions by using an abundant and inexpensive metal. The native oxidation process of this metal is often viewed as a limitation for its application in plasmonics. Here, we show that in close gap configurations, the high refractive index of the native aluminum oxide helps in squeezing the plasmonic mode in extremely reduced size volumes, providing a higher EM near-field confinement and enhancement in the bowtie antenna gaps than achieved in the pure aluminum counterpart.

Thin Diamond Film on Silicon Substrates for Pressure Sensor Fabrication.

Thin polycrystalline diamond films chemically vapor deposited on thinned silicon substrates were used as membranes for pressure sensor fabrication by means of selective chemical etching of silicon. The sensing element is based on a simple low-finesse Fabry-Pérot (FP) interferometer. The FP cavity is defined by the end-face of a single mode fiber and the diamond diaphragm surface.

Fabrication and characterization of AlN-based flexible piezoelectric pressure sensor integrated into an implantable artificial pancreas.

This study reports on the fabrication and characterization of an event detection subsystem composed of a flexible piezoelectric pressure sensor and the electronic interface to be integrated into an implantable artificial pancreas (IAP) for diabetic patients. The developed sensor is made of an AlN layer, sandwiched between two Ti electrodes, sputtered on Kapton substrate, with a preferential orientation along c-axis which guarantees the best piezoelectric response. The IAP is made of an intestinal wall-interfaced refilling module, able to dock an ingestible insulin capsule.

AI-Based Early Change Detection in Smart Living Environments.

In the smart environments we live today, a great variety of heterogeneous sensors are being increasingly deployed with the aim of providing more and more value-added services. This huge availability of sensor data, together with emerging Artificial Intelligence (AI) methods for Big Data analytics, can yield a wide array of actionable insights to help older adults continue to live independently with minimal support of caregivers. In this regard, there is a growing demand for technological solutions able to monitor human activities and vital signs in order to early detect abnormal conditions, avoiding the caregivers' daily check of the care recipient.

Immune Profiling of Polysaccharide Submicron Vesicles.

Alginate (ALG) and chitosan (CS) have been extensively used for biomedical applications; however, data relative to immune responses exerted by them are scarce. We synthesized a submicron vesicle system (SV) displaying a CS shell over an ALG core. Intravenous injection of these promising carriers could be a possible route of delivery; therefore, we evaluated their impact on human peripheral blood mononuclear cells (PBMCs).

Coalescence of silver clusters by immersion in diluted HF solution.

The galvanic displacement deposition of silver on H-terminated Si (100) in the time scale of seconds is instantaneous and characterized by a cluster density of 10(11)-10(12) cm(-2). The amount of deposited Ag follows a t(1/2) dependence in agreement with a Cottrell diffusion limited mechanism. At the same time, during the deposition, the cluster density reduces by a factor 5.

PDMS/Kapton interface plasma treatment effects on the polymeric package for a wearable thermoelectric generator.

The present work highlights the progress in the field of polymeric package reliability engineering for a flexible thermoelectric generator realized by thin-film technology on a Kapton substrate. The effects of different plasma treatments on the mechanical performance at the interface of a poly(dimethylsiloxane) (PDMS)/Kapton assembly were investigated. To increase the package mechanical stability of the realized wearable power source, the Kapton surface wettability after plasma exposure was investigated by static contact-angle measurements using deionized water and PDMS as test liquids.

A supramolecular approach to sub-ppb aromatic VOC detection in air.

Micromachining technology is coupled to a selective pre-concentration material for the development of a portable sub-ppb level monitoring system for aromatic volatile organic compounds (VOC); the high sensitivity of Metal Oxide (MOX) gas sensors is combined with a supramolecular concentration unit to increase selectivity and reduce the detection limits.