Cryptogenic organizing pneumonia (COP) is typically treated with corticosteroids, but this study compares the effectiveness of clarithromycin (CAM) versus prednisone (PRE) in patients without respiratory failure.
Over 15 years, 40 patients received CAM and 22 received PRE, with similar clinical presentations but notable differences in treatment response and side effects.
CAM showed a better tolerance and fewer relapses (10% vs. 54.5%) compared to PRE, suggesting it's a viable alternative for patients with normal pulmonary function, although not effective for everyone.