Is Progesterone Receptor a Neglected Feature in Breast Cancer? A Retrospective Study Analysing the Clinicopathological Characteristics of Breast Cancer Based on Progesterone Receptor Status.

Purpose: The aim of this study is to analyse PR independently and its relationship with demographic and clinicopathological information.

Introduction: Steroid hormones, particularly estrogen and progesterone, play a crucial role in breast cancer (BC) etiology. Research attention has focused mainly on estrogen while the progesterone impact on breast cancer has yet to be fully uncover.

Longitudinal analysis of echocardiographic and cardiac biomarker variables in dogs with atrial fibrillation: The optimal rate control in dogs with atrial fibrillation II study.

Background: Rate control (RC; meanHR ≤ 125 bpm) increases survival in dogs with atrial fibrillation (AF). The mechanisms remain unclear.

Hypothesis/objectives: Investigate echocardiographic and biomarker differences between RC and non-RC (NRC) dogs.

Development and Validation of the Serious Educational Game in Nursing Appraisal Scale.

Objectives: This study aims to develop and validate the Serious Educational Game in Nursing Appraisal Scale (SEGiNAS), a tool designed to evaluate the implementation of serious games within nurse education contexts of quantity of process, quality of process, and learning outcomes.

Methods And Materials: This methodological and psychometric study aimed to develop and validate a scale. The item generation phase was based on the cognitive theory of multimedia learning, resulting in a 20-item scale.

Current State of Canine in Portugal.

The favourable geo-climatic conditions in Portugal have made it highly conducive to the development of in dogs, leading to its identification as an endemic region. This nematode is rapidly spreading across Europe, particularly in northeastern countries. The objective of this study was to provide an updated assessment of the prevalence of this disease in Portuguese dogs, analysing the results in relation to epidemiological and geo-environmental factors, and to identify potential risk factors.

Needs of Family Caregivers of People with Lower Limb Amputations: A Scoping Review.

Lower limb amputation affects several parameters of a patient's life. Family caregivers providing care for these patients experience multiple feelings and needs; knowing caregivers' needs is essential to prepare them for this new role, as well as the health planning of this type of care. This scoping review aimed to identify and map the needs of family caregivers of people with lower limb amputations.

Environmental health impacts and controlling measures of anthropogenic activities on groundwater quality in Southwestern Nigeria.

Groundwater is the major source of drinking water in virtually all the regions of Nigeria, including the southwestern region. It is an indispensable source of drinking water that many individuals are dependent upon for daily activities in Nigeria. However, the spontaneous rise in various forms of industrialization and other anthropogenic activities of man within the southwestern region has immensely polluted these water sources.

The assessment of researchers' competence in experimental procedures with laboratory animals: A three-step methodology to develop a global rating scale.

To conduct animal experiments, researchers must be competent to handle and perform interventions on living animals in compliance with regulations. Laboratory animal science training programmes and licensing bodies therefore need to be able to reliably ensure and certify the professional competence of researchers and technicians. This requires access to assessment strategies which can verify knowledge as well as capturing performative and behavioural dimensions of assessment.

Review: Antibacterial components of the Bivalve's immune system and the potential of freshwater bivalves as a source of new antibacterial compounds.

Antibacterial research is reaching new heights due to the increasing demand for the discovery of new substances capable of inhibiting bacteria, especially to respond to the appearance of more and more multi-resistant strains. Bivalves show enormous potential for the finding of new antibacterial compounds, although for that to be further explored, more research needs to be made regarding the immune system of these organisms. Beyond their primary cellular component responsible for bacterial recognition and destruction, the haemocytes, bivalves have various other antibacterial units dissolved in the haemolymph that intervene in the defense against bacterial infections, from the recognition factors that detect different bacteria to the effector molecules carrying destructive properties.