[The effectiveness of forensic medical expert assessment of fatal multiple shooting wounds].

Objective - to evaluate the practical solution of forensic medical problems in cases of fatal multiple gunshot wounds. The materials of 426 forensic medical expert studies of fatal gunshot wounds were studied. The reasons for the insufficient realization of practical expert problems' solution have been established.

[Introduction to forensic gerontology].

Objective - to substantiate the identification of a new direction in forensic medicine - forensic gerontology. A statistical analysis of the structure of forensic medical research of corpses in terms of age for a twenty-year period has been carried out. The data on the features of the expert assessment of injuries in old age taking into account geriatric syndromes and aging syndromes have been analyzed.

[Life pages and scientific activity of Professor R.V. Babakhanyan].

Professor R.V. Babakhanyan - Head of the Department of Forensic Medicine and Law, Pavlov First Saint Petersburg State Medical University is one of the notable teachers and scientists among the St.

[120 years of the Department of Forensic Medicine and law, I.P. Pavlov First Saint Petersburg State Medical University].

The history of the development of the Department of Forensic Medicine and law, Pavlov First Leningrad (Saint Petersburg) State Medical University is outlined. The history is presented in the form of the scientific contribution of the heads of the Department of Forensic Medicine to the development of scientific activities of national forensic medicine. The stated period covers 120 years, starting from 1901.

[Heart damage in the combined types of systemic amyloidosis].

Unlabelled: The cardiovascular system is a common target of systemic amyloidosis (SA); amyloid light chain (AL) cardiac amyloidosis (AL-CA), the wild-type transthyretin (ATTRwt-CA), and mutant-type transthyretin (ATTRmt-CA) are the most studied types of SA. The literature describes only single cases of two types of SA in the same patient.

Objective: To identify and determine the clinical and morphological characteristics of combined types of SA in patients with biventricular chronic heart failure (CHF).

[An associations of possible genetic risk markers for Internet addiction with childhood trauma experience and personality traits in young adults : preliminary results].

Objective: To study was to test an associations of the preliminary genetic risk markers for Internet addiction (IA) with clinical, psychological and personality characteristics, taking into account the childhood traumatic experience, in 44 IA persons compared with 120 healthy individuals.

Material And Methods: The study included 164 participants: 44 individuals with IZ (group IZ), male and female, aged 16 to 30 years in the absence of diagnoses of mental health problems. diseases from rubrics F00-09 and F20-29 (ICD-10) and 120 healthy (control group).

[Indicators of oral fluid and their correction by means of hygiene in elderly people with general somatic diseases.].

The results of the study of oral fluid in older persons with somatic pathology, which was followed for 1 month, are presented. The acid-base state of the oral fluid was evaluated, and the viscosity of the oral fluid was determined. According to the results of the study of oral fluid and its correction by means of hygiene in older persons with somatic diseases, the dynamics of the indicators of the acid-base state of the oral fluid, its shift to the alkaline side and the positive dynamics of the effect of the viscosity of the oral fluid were noted.

The association of obesity with eating disorders risk: online survey of a large cohort of Russian-speaking individuals seeking medical weight correction assistance.

Background: Eating Disorders pose a serious health risk to individuals. Often, eating disorder symptoms are overlooked when assessing obesity risk. The current cross-sectional study was focused on the search of association between disordered eating behaviors evaluated by Eating Attitudes Test 26 (EAT-26) and obesity in a large cohort of Russian-speaking adults seeking online assistance with medical weight correction.

[On the issue of a comprehensive diagnosis of death coming in the late postmortem period].

According to specialized literature and the results of our own experiments to carry out a comprehensive study to find criteria for determining the time of death in the late postmortem period. It turned out that a combined assessment of microbiological, entomological and biophysical data obtained in the study of a corpse is advisable for medical diagnostics of the duration of the postmortem interval, which does not exclude the need to compare them with the results obtained by traditional morphological methods. From an applied point of view, it is very important to «standardize» the conditions of such studies.

[Airway support for endoscopic endonasal surgery in gerontology.].

Airway patency during ENT surgery in general anesthesia is a serious problem. It is important to manage the degree of intraoperative bleeding to improve the visibility of the surgical site and reduce the risk of complications. Airway management may affect the severity of intraoperative bleeding.

[Loss of masticatory apparatus integrity - Disability or Disablement.].

We examined 408 patients (151 male, 257 female) in an age range from 54 to 85 years (mean age 73,9±4,9) performing clinical (anamnesis, visual analysis, palpation, percussion, auscultation) sociological (GOHAI), additional (chewing efficiency evaluation, phonetic analysis, weight deficit of body calculation, OPG, CBCT) assessment. Among 322 of examined subjects working syndromological diagnosis was «decompensated dentition» related to lower jaw in 167 cases, 65 to upper jaw, 90 to both upper and lower jaws (altogether 412 dental arches). Chewing efficiency among edentulous patients was low considering that majority of patients had dentures.

[Traumatic defeats of the oral mucosa among people of the senior age groups: occurrence, consequences and treatment.].

Traumatic damages to the oral mucosa are the main predisposing factor for the development of the oncostomatological pathology among the old people. The aim of the investigation was to study the occurrence of traumatic lesions of the oral mucosa among people of old age groups and estimate the effectiveness of their treatment using modern domestic remedies. 967 people (569 males and 398 females) from 19 to 82 years old were examined to determine the occurrence of traumatic oral mucosal pathology.

[Terahertz modulated infrared radiation in the complex treatment of patients in the acute period of ischemic stroke].

Unlabelled: Ischemic stroke (IS) is a serious medical and social problem due to the widespread prevalence, profound and long-term disability of patients. The effectiveness of pharmaceutical neuroprotection in IS remains low which necessitates the investigation of new therapeutic methods in post-stroke patients.

Objective: The rationale for the use of infrared (IR) radiation with terahertz (THz) modulation in the complex treatment of patients in the acute period of IS.

[Abnormal development of the hard palate revealed during the forensic examination of bone remains].

In the forensic practice of examining bone remains there are cases of anomalies' detection of the skeleton development which have a high identification value for the search for a missing person. The most valuable ones are the features of the facial skull anatomical structure since they are usually well visible and recorded in photographic and medical documents. In the presented case an anomaly in the hard palate development was revealed on the skull of an unknown person found in the Leningrad region - a cleft caused by its underdevelopment.

Management of Cough in Patients with Chronic Obstructive Pulmonary Disease: Results of the Multicenter Randomized Placebo-Controlled Clinical Trial.

Background: Chronic cough declines quality of life and increases risk of complications in patients with chronic obstructive pulmonary disease (COPD). Reducing cough severity and associated negative effects is important therapeutic goal in COPD. Rengalin with anti- and protussive activity is based on technologically processed antibodies to bradykinin, histamine and morphine.

[Osteoplastic operations in the anterior part of the mandible for correction of malocclusion].

Correction of disorders during transformation into one of the most difficult tasks, both in orthodontics and in maxillofacial (orthognathic) surgery. This article presents two clinical cases of median osteotomy/ostectomy. The stages of operations are described.

[Morphological characteristics of pulmonary tuberculosis concurrent with lung cancer].

Unlabelled: The pathogenetic relationship between pulmonary tuberculosis and lung cancer in their concurrence is now still the subject of discussion.

Objective: To study the pathogenetic relationship between pulmonary tuberculosis and lung cancer.

Material And Methods: The investigators examined surgical material from 51 patients (41 men) aged 41-73 years (mean age, 63.

Presence of viremia during febrile neutropenic episodes in patients undergoing chemotherapy for malignant neoplasms.

The importance of viral infections as a leading cause of morbidity and mortality is well documented in severely immunosuppressed patients undergoing allogeneic stem cell transplantation. By contrast, viral infections generally receive less attention in patients with malignant disorders undergoing chemotherapy, where the onset of neutropenic fever is mostly associated with bacterial or fungal infections, and screening for viral infections is not routinely performed. To address the occurrence of invasive viral infections in a clinical setting commonly associated with less pronounced immunosuppression, we have prospectively screened 237 febrile neutropenic episodes in pediatric (n = 77) and adult (n = 69) patients undergoing intensive chemotherapy, primarily for treatment of acute leukemia.

[Prospects for molecular-genetic support of research on proteolytics in the necrobiome composition].

The aim of this work is to monitor the state of the proteolytic community in time and space for the subsequent development of approaches to an objective assessment of the late postmortem period. The study proposes a combination of standard bacterioscopic and bacteriological research methods with methods of molecular biology and genetics, which make it possible to identify species and strains of mammalian corpses' proteolytics at the level of specific DNA or RNA. On the basis of phenotypic traits and a comparative analysis of the nucleotide sequences of genes encoding 16S rRNA, the species belonging of the isolated strains was proved.

[To the study of the corpse tissues' impedance dynamics in the late postmortem period].

The purpose of this work is to establish the dynamics of the electrical conductivity of various corpse tissues using impedance measurements to assess this method for diagnosing the time of death. It was studied the values of the tissue impedance from the corpses of 8 persons of both sexes and different ages (30-50 years) who died from various causes, with the known date of death. A Keysight U1731 parting was used with two probes, which are stainless steel needles with a diameter of 0.

[Low-pressure pneumoperitoneum with abdominal elevation in laparoscopic radical prosta-tectomy in elderly patients with a localized form of prostate cancer.].

Prostate cancer is an actual problem among males of older age groups, while the concomi-tant premorbid background of this category of patients often leads to the development of postopera-tive complications using the standard surgical method. The article presents the results of using low-pressure pneumoperitoneum with anterior abdominal wall lifting for laparoscopic radical prostatec-tomy in elderly patients with a localized form of prostate cancer. Convincingly shown that the use of low-pressure techniques pneumoperitoneum with lifting anterior abdominal wall ensures satis-factory operating field, obtains stable indicators of operational monitoring and allow to reduce the duration of the operation, as well as reduce the duration of hospitalization and incidence of postoperative complications.

[Age-related issues of the quality of life in hearing impaired patients.].

The aim of the research was to study the quality of life in hearing impaired patients of different age. 100 patients referred to the city audiology centre because of their hearing disorders were examined: 50 patients from 34 to 59 years old and 50 patients from 60 years and older, from which 32 patients were of older age (60 to 74 years old) and 18 of oldest age (75 to 86 years old). A degree of hearing loss was assessed according to results of pure tone audiometry.

[Sepsis: from systemic inflammatory response syndrome to organ dysfunction].

Based on their extensive experience and literature data, the author outlines difficulties in the morphological diagnosis of sepsis, by taking into account the current clinical classification. Occurring not only in sepsis and lacking clear morphological criteria, a systemic inflammatory response and organ dysfunction cannot be absolute signs of sepsis diagnosis. The author gives the morphological characteristics of the systemic inflammatory response, septic shock, and organ dysfunction.

[Chronic pelvic pain syndrome in women: diagnostic and therapeutic aspects].

Chronic pelvic pain syndrome (PPS) refers to pain of three to six months duration (or longer) that occurs below the umbilicus. PPS is considered a form of chronic regional pain syndrome or functional somatic pain syndrome. Multimodal ollaborative and patient-centered approach is critical component of treatment for women with CPPS.

[Radiation-protective agent and anti-aging agents: random and predictable matches.].

Radiation-protective and anti-aging properties are often combined. Combination of this properties is linked to the common mechanisms of action such as direct and indirect antioxidant activities, inhibition of free radicals formation, increase resistance to stress impacts at the cellular level, acceleration of DNA reparation, prevention of chronic diseases linked to abnormalities in regeneration processes, activation of immune inflammatory processes and carcinogenesis. Regulation of cell cycle and apoptosis can often be considered as an implementing driver of radiation-protective and anti-aging activities.