[PUBLIC AWARENESS ABOUT INTELLECTUAL DISABILITY, ITS CAUSES AND EFFECTIVENESS OF INTERVENTIONS BY SPECIALISTS].

Unlabelled: The purpose of the study is to analyze perception of the adult population about intellectual disability (ID), its causes and effectiveness of specialist interventions.

Material And Methods: 1119 people were interviewed (men - 441, women - 678) aged 18 to 85 years (mean age - 34.3 ± 14.

The influence of social and medical factors on the quality of life in elderly and senile people.

The object of the study was senile people, who sought dental orthopedic care in municipal healthcare institutions of the town of Cheboksary, the Chuvash Republic. The sample size was 1 000 people. The obtained quantitative indicators were subjected to statistical processing using parametric and nonparametric statistical methods.

[The health of children of adolescent age delivered on time with light and large body mass].

The need to preserve and promote health of children determine one of the basic directions of development of public social policy. It is the most important strategic purpose of modern children health care, since from it depend health of the nation, increasing of life expectancy and national economic potential.Purpose of the study is to assess health status of children of adolescent age born at term with diagnosis "fetus with low birth weight for gestational age" and with large body mass.

Effect of a Substituent in the Fourth Position on the Optical Properties of 2-Oxonicotinonitriles.

Based on six representatives of 2-oxonicotinonitriles, the effect of the nature of the substituent in the fourth position of the pyridine system on the photophysical characteristics was studied. The role of the donor/acceptor nature of the substituent and the solvent nature in the absorbing and fluorescent properties of the compounds was shown.

[Testosterone and Alzheimer's disease].

Alzheimer's disease (AD) is a neurodegenerative disease that causes dementia in half of the cases. Asthma is usually found in people over 65 years of age. The etiopathogenesis of the disease is multifactorial and includes genetic factors, nutritional disorders, mitochondrial dysfunction, oxidative stress, and aging.

Megakaryocytes of the Spleen in Experimental Amyloidosis and Effect of Red Wine.

Amyloidosis was modeled in young mice by administration of aqueous solution of soy cream substitute and then, amyloidogenesis was corrected by oral administration of dry red wine. In mice with amyloidosis, the area of megakaryocytes decreased by 1.69 times, the relative content of oxyphilic forms of megakaryocytes increased by 4.

Wavelets and digital filters designed and synthesized in the time and frequency domains.

The relevance of the problem under study is due to the fact that the comparison is made for wavelets constructed in the time and frequency domains. The wavelets constructed in the time domain include all discrete wavelets, as well as continuous wavelets based on derivatives of the Gaussian function. This article discusses the possibility of implementing algorithms for multiscale analysis of one-dimensional and two-dimensional signals with the above-mentioned wavelets and wavelets constructed in the frequency domain.

Effect of Bone Marrow Autotransplantation on the Numerical Population of Tryptase-Positive Mast Cells, Heparin Sulfation Degree, and Histamine Content.

We studied the effect of bone marrow autotransplantation on the morphofunctional properties and numerical population of mast cells. The experiments were performed on 4-monthold male mice. The animals received an injection of a suspension of bone marrow obtained from the femoral epiphyses of these animals into the caudal vein.

Preparation and Characterization of a Flexible rGO-PTFE Film for a Supercapacitor Current Collector.

A mixture of water suspensions of graphene oxide (GO) and polytetrafluoroethylene (PTFE) was used to make the films GO-PTFE (50:50). They became conductive (2.0-2.

Hepatic Mast Cells in Mice with Experimental Amyloidosis.

We studied the response of mast cells in mouse liver to experimental amyloidosis modeled by administration of aqueous solution of soy cream substitute and its correction by spontaneous dry red wine intake per os. Mast cells in mice with amyloidosis and intact mice were presented by α-ortho- and β-metachromatic non-degranulating forms. In mice with amyloidosis, the relative content of β1-metachromatic mast cells in the capsule and parenchyma of the liver was by 1.

Effects of Bone Marrow Autotransplantation on the Bone Marrow Neurotransmitter Structures.

Morphological structures involved in local regulation of tissue processes and the neurotransmitters they produce are assumed to play an important role in the pathogenesis of oncological diseases. We studied the dynamics of neurotransmitter cell counts and distribution of catecholamines and serotonin in them and analyzed proliferative activity of hemopoietic cells in the bone marrow of mice after bone marrow autotransplantation. The bone marrow of male mice was studied by fluorescent and immunohistochemical methods after injection of the bone marrow from the same mouse into the caudal vein.

[On patterns of human height distributions relative to the specific length of the foot].

The purpose of the study is to clarify the patterns of distribution of height measurements relative to a specific length of a foot in humans, in order to use them for more accurate and reliable determination of body length (height). 15,892 people of mixed population (9814 men and 6078 women of 49 nationalities) aged from 20 to 50 years were examined. Their heights and their foot lengths were measured, and the coefficients of the ratios were calculated.

Cellular Composition and Expression of Cell Proliferation and Apoptosis Markers in Bone Marrow Cells after Heterotransplantation.

The effects of heterotransplantation on bone marrow structures were studied in experimental male mice. Suspension of the bone marrow from feline femur (1 ml bone marrow diluted in isotonic saline, 1:2) was injected into the caudal vein. Heterotransplantation led to an increase in the level of serotonin involved in cell differentiation.

[European registry Helicobacter pylori (Hp-EuReg): how has clinical practice changed in Russia from 2013 to 2018 years].

Unlabelled: The multicenter prospective observational study initiated by the European Helicobacter and Microbiota Study Group (EHMSG) is conducted in 27 countries in Europe. The data from the Russian part of the European registry for the management of Helicobacter pylori infection (European Registry on the management of Helicobacter pylori infection, protocol: "Hp-EuReg") allows us to analyze the real clinical practice of diagnosis and treatment of H. pylori and compare it with international recommendations.

[Infant feeding in the rural area of Chuvash Republic and Nizhny Novgorod Region].

The nature of feeding in the first year of life affects the health of the child in all subsequent periods of life. Objective - the article is devoted to the study of the state of feeding the children of the first year of life living in rural areas. The study was carried out on the basis of three children's clinics in the Chuvash Republic and the Nizhny Novgorod region by random sampling using an anonymous questionnaire of women who had children aged 1 to 2 years living in the rural areas of the Chuvash Republic and the Nizhny Novgorod Region (140 and 60 women, respectively).

New Experimental Facts on the Influence of Secondary Immunodeficiency on the Morphology and Biological Activity of Colorectal Tumor.

Colorectal tumors were studied 5 months after carcinogen injection to outbred albino rats with secondary immunodeficiency by common histological and immunobiochemical methods with the use of monoclonal and polyclonal antibodies to Ki-67, Bcl-2, p53, and VEGF. Injection of carcinogen to intact animals led to the formation of adenocarcinomas with high and moderate cell differentiation in the colon, while injection of carcinogen to animals with immunodeficiency was associated with a 1.5-fold higher incidence of GRADE 2 and GRADE 3 adenocarcinomas with more aggressive morphological phenotype and appearance of distant metastases.

[Morphological changes of cornea in children with hyperopia in the immediate and remote postoperative period after laser keratomieleusis according to confocal microscopy data].

Unlabelled: Studying morphological changes of cornea in the remote postoperative period is becoming increasingly relevant with refractive surgeries being adapted for children.

Purpose: comparative analysis of keratocyte density and hystomorphologic changes of cornea after laser in situ keratomieleusis (LASIK) and femtosecond laser-assisted LASIK (FS-LASIK) in children with hyperopia.

Material And Methods: 109 patients aged 6-17 years in 2 groups were examined with 'Confoscan-4' confocal microscope.

[Association of sleep disorders with headache].

Aim: The aim of the present study was to investigate the connection of sleep disorders (SD) with a headache (HA) among the representative sample of population.

Material And Methods: 1115 inhabitants of Chuvashia (491 men and 624 women) aged from 18 to 70 years old have been interviewed (middle age 38.7±13.

[Comparative analysis of corneal aberrations after intrastromal segments and MyoRing implantation using femtosecond laser in patients with keratoconus].

Aim: to comparatively analyze corneal aberrations after intrastromal corneal segments (ICS) and MyoRing implantation using femtosecond laser in patients with stage II-III keratoconus (KC) by Pentacam examination.

Material And Methods: We have operated on 135 patients (145 eyes) with stage II or III KC. Depending on surgical technique, all patients were divided into two groups.

[Individual resistance card in health care for patients with urogenital diseases].

Unlabelled: Currently, practical health care does not have a means to transfer patients health data when they change the place of residence and employment. In this regard, there was a need to develop a health-related instrument to accompany an individual when he/she changes the place of residence and work. The aim of the study was to develop an "individual resistance card" to use in health care for patients with diseases of the genitourinary system.

Systemic Amyloidosis Model on Young Mice.

Subcutaneous daily injection (with neglect of aseptics) of 0.5 ml solution of soybean cream substitute (10% volume in distilled water) during 30 days caused systemic amyloidosis in 30-day-old mice. All the known methods for induction of systemic amyloidosis are based on the use of old animals, as senile tissue bradytrophy allows effective simulation of amyloidosis.

Morphology and Immunohistochemical Phenotype of the Thymus in Secondary Immunodeficiency.

The thymus of outbred male rats 5 months after splenectomy (experimental secondary immunodeficiency) was studied by common histological and immunohistochemical methods using monoclonal and polyclonal antibodies to CD3, CD30, CD68, synaptophysin, to S100, p53, bcl-2, and Ki-67 proteins. Removal of the spleen led to acute involution of the thymic parenchyma, which was replaced by the adipose tissue and was associated with restructuring of the thymopoietic and nonthymopoietic components of the gland, changes in cellular composition and antigenic phenotype of the lobular cortical and medullary matter, and by reduction of cell proliferation.

[The influence of alcohol consumption on the chronological patterns of sudden cardiac death].

The objective of the present study was the retrospective analysis of the materials collected by the Republican Bureau of Forensic Medical Expertise, Ministry of Health and Social Development of Chuvash Republic, during the period from 1997 till 2002 for the elucidation of the chronological patterns of sudden cardiac death (SCD) associated with alcohol consumption depending on the sex and age of the victims, days of the week and months of the year as well as weather conditions. It was shown that the peak of mortality among men and women taking no alcohol fell on Monday. It was highest in May and decreased by February.

Thymic Structures Containing Somatostatin.

Double immunofluorescent staining confirmed co-expression of somatostatin (neuropeptide) and antigen-presenting cells of macrophage origin expressing major histocompatibility complex class II molecules in the intact thymus. The results confirmed cooperation of the neuropeptide and immunocompetent systems.

Luminescent-morphological features of mouse spleen after acupuncture.

The effectiveness of acupuncture contributing to stimulation of morphological organization and altering the dynamics of histamine in the spleen of mice already in the first days after treatment was validated using the methods of luminescent and light microscopy.