ANTIOXIDANT-PROOXIDANT BALANCE OF THE KIDNEYS IN RATS OF DIFFERENT AGES UNDER CONDITIONS OF EXPERIMENTAL CRANIOSKELETAL TRAUMA.

Objective: The aim: To determine the peculiarities of the antioxidant-prooxidant balance in the kidney of rats of different ages under conditions of experimental cranioskeletal trauma (CST).

Patients And Methods: Materials and methods: The experiments involved 147 male white Wistar rats of different age groups. The first experimental group included immature animals aged 100-120 days.

[CLINICAL CHARACTERISTICS OF DISEASES OF THE ORAL MUCOSA IN PATIENTS WHO HAVE UNDERGONE COVID-19 - WHAT DOES A DENTIST NEED TO KNOW IN A PANDEMIC?].

ization and unification of diseases of the oral mucosa in patients who underwent Covid-19, in order to increase the effectiveness of qualified dental care for this group of people in a pandemic and create conditions for continuous professional development of dentists. 42 patients were attended, who came through Covid-19, aged 36 to 70 years, who applied independently or were referred by doctors of private clinics in the city of Ternopil. The gender distribution of patients was 19 males and 23 females.

[VIOLATION OF THE PROOXIDANT-ANTIOXIDANT BALANCE IN THE SPLEEN TISSUE UNDER EXPERIMENTAL CARCINOGENESIS].

This study was devoted to the investigation of antioxidant homeostasis in spleen tissue of white rats in the dynamics of development of colon adenocarcinoma induced by the introduction of sym-dimethylhydrazine (DMH). The effectiveness of the antioxidant barrier (Cu,Zn-superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, reduced glutathione) and oxidative damage products (TBARS, advanced oxidation protein products, diene and triene conjugates, Schiff bases) were measured in the homogenate of spleen tissue. A violation of the redox balance due to the accumulation of lipid peroxidation products, a decrease in the activity of antioxidant enzymes and antioxidant mediators of non-enzymatic nature was established.