4 results match your criteria: "I. Franko University[Affiliation]"

It have been found that intraperitoneal alpha-ketoglutarate injection (20 mg/100 g body weight) results in increase in the influence of cholinergic regulation mechanisms. It also results in increase of aminotransferase activity on background of the decrease of succinate dehydrogenase activity in liver and pancreas tissues and in small intestines mucous. Activity of transamination enzymes and succinate dehydrogenase activity is much higher in the case of rats with high hypoxia resistance, alpha-ketoglutarate injection results in increase of transamination enzymes activity in the organisms of rats with low resistance to hypoxia up to the control level of rats with high resistance, and simultaneously increases rats resistance to hypoxia.

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The model of permeable gastric glands obtained by its incubation with digiton (15 mg/ml) had investigated. It was shown, that stimulated influence of Ca2+ ions on pepsinogen extrusion completely or partly reproduced by cations of transient metals. Stimulated effects of cations of metals (5 x 10(-4) M) decrease in such order: Ca2+ > Cd2+ > Mn2+ > Co2+ > La3+.

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We have investigate the effect of sodium ketoglutarate intraperitoneal injection (20 mg/100 g body weight) made 0.5 hour before and 1, 2 and 3 hours after total X-ray treatment (259 mKl/kg) on the survival of rats. Simultaneously we have define changes in cholinesterase-acetylcholine system and content of adrenaline and noradrenaline in liver and pancreas tissues, small intestines mucous and in blood.

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Kanamycin resistance gene (kmr) from the overproducing mutant strain of Streptomyces kanamyceticus ISP1375 (strain 1) and from its gentamicin-resistant mutant were cloned into the high copy number vector pIJ702 and transformed into S. lividans 66. This gene provides resistance to kanamycin, gentamicin, sisomicin and tobramicin.

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