5,078 results match your criteria: "I-Shou University[Affiliation]"
J Oral Biosci
December 2024
Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan R.O.C; Marine Biology and Cetacean Research Center, National Cheng Kung University, Tainan, Taiwan R.O.C. Electronic address:
Objective: Drug resistance and subsequent adverse effects, such as cancer cachexia, limit the clinical use of cisplatin. Oligonol® (Olg), a low-molecular-weight polyphenol, exhibits NF-κB inhibitory properties. NF-κB activation has been implicated in cisplatin resistance of cancer cells and skeletal muscle wasting.
View Article and Find Full Text PDFClin Ther
December 2024
Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan; School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:
Purpose: Intraoperative topical vancomycin has been widely used in several surgical fields to prevent wound infection. However, there have been limited studies on the systemic exposure of topical vancomycin. The aim of this study was to investigate systemic exposure after topical vancomycin over the sternal edge in cardiac surgical patients.
View Article and Find Full Text PDFSurg Obes Relat Dis
November 2024
Bariatric and Metabolism International Surgery Center, E-Da Hospital, Kaohsiung, Taiwan; School of Medicine for International Students, College of Medicine, I-Shou University, Kaohsiung, Taiwan; Division of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan. Electronic address:
Background: Little is known about the associations between changes in hepatic steatosis and changes in abdominal adiposity after metabolic bariatric surgery.
Objectives: To evaluate the serial changes in hepatic steatosis and abdominal adiposity following sleeve gastrectomy (SG).
Setting: University hospital, Taiwan.
J Antimicrob Chemother
December 2024
Department of Medical Laboratory Science, I-Shou University, Kaohsiung City, Taiwan.
Objectives: Group A Streptococcus (GAS) results in invasive diseases. Our published studies show that AR-12 can directly kill GAS. However, AR-12 is toxic to the human microvascular endothelial cells (HMEC-1 cells) even at its MIC.
View Article and Find Full Text PDFChild Adolesc Psychiatry Ment Health
December 2024
Department of Anesthesiology, Chi Mei Medical Center, No.901, ChungHwa Road, YungKung Dist, Tainan, 71004, Taiwan.
Background: We aimed at investigating the efficacies of probiotics in alleviating the core and associated symptoms of autism spectrum disorder (ASD).
Methods: Randomized placebo-controlled trials were identified from major electronic databases from inception to Nov 2023. The outcomes of interests including improvements in the total and associated symptoms of ASD were quantitatively expressed as effect size (ES) based on standardized mean difference (SMD) with 95% confidence interval (CI).
Health Sci Rep
December 2024
Division of Infectious Diseases, Department of Medicine Taipei Veterans General Hospital Taipei Taiwan.
Background And Aims: People living with human immunodeficiency virus (HIV, PLWH) are aging, and there are growing concerns regarding combined antiretroviral therapy (cART)-associated negative metabolic consequences. We aimed to investigate the metabolic outcomes of PLWH by replacing rilpivirine (RPV)/tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) with RPV/tenofovir alafenamide (TAF)/FTC.
Methods: This retrospective study enrolled PLWH who changed from RPV/TDF/FTC to RPV/TAF/FTC between January 2019 and September 2023.
BMC Complement Med Ther
December 2024
Department of Pediatrics, E-Da Hospital, I-Shou University, No. 1, Yi-Da Road, Yan-Chao District, Kaohsiung City, 82445, Taiwan, R.O.C..
Background: Esophageal achalasia, a primary disorder impacting the lower esophageal sphincter (LES), presents symptoms such as dysphagia, regurgitation, chest pain, and weight loss. Traditional treatments, including calcium channel blockers and nitrates, offer limited relief, prompting exploration into alternative therapies. This study examines the efficacy of Traditional Chinese Medicine (TCM), focusing on Coptis chinensis (C.
View Article and Find Full Text PDFPharmacopsychiatry
December 2024
Department of Psychiatry, Beitou Branch, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Background: This study aimed to assess the association between the risk of colorectal cancer (CRC) and exposure to mood stabilizers, antidepressants, and antipsychotics in patients with affective disorders.
Methods: This nested case-control study used data from the National Health Insurance Database of Taiwan collected between 2001 and 2011. All participants in this study had affective disorders.
Diagnostics (Basel)
November 2024
Department of Emergency Medicine, E-Da Hospital, I-Shou University, Kaohsiung 824005, Taiwan.
Background And Objectives: Chest X-ray (CXR) images are commonly used to diagnose respiratory and cardiovascular diseases. However, traditional manual interpretation is often subjective, time-consuming, and prone to errors, leading to inconsistent detection accuracy and poor generalization. In this paper, we present deep learning-based object detection methods for automatically identifying and annotating abnormal regions in CXR images.
View Article and Find Full Text PDFJ Clin Anesth
December 2024
Department of Anesthesiology, E-Da Hospital, I-Shou University, Kaohsiung City, Taiwan. Electronic address:
Anaesthesia
December 2024
School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung City, Taiwan.
Introduction: General anaesthesia and regional anaesthesia are used for hip and knee arthroplasty but their impact on long-term outcomes remains unclear. This study aimed to compare one-year clinical outcomes and healthcare utilisation in patients receiving general or regional anaesthesia for hip or knee arthroplasty.
Methods: Using data from the TriNetX Global Collaborative Network, we conducted a retrospective analysis of 247,142 patients aged 40-90 y who underwent hip or knee arthroplasty between 2010 and 2023.
Biomater Res
December 2024
Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
The presence of anti-polyethylene glycol (anti-PEG) antibodies can hinder the therapeutic efficacy of PEGylated drugs. With the widespread use of a PEGylated coronavirus disease 2019 (COVID-19) messenger RNA vaccine (Comirnaty), the impact of pre-existing anti-PEG antibodies on vaccine potency has become a point of debate. To investigate this, we established mouse models with pre-existing anti-PEG antibodies and divided them into 3 groups: group 1 with anti-PEG immunoglobulin G + immunoglobulin M concentrations of 0.
View Article and Find Full Text PDFJ Viral Hepat
January 2025
School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
Hepatitis C virus (HCV) infection is associated with a myriad of extrahepatic manifestations (EHM), as well as the production of autoantibodies, including rheumatoid factor (RF). This study aims to elucidate whether serum levels of RF change before and after HCV eradication, and whether these changes differ according to the type of therapy used. This is a retrospective cohort study of adults with chronic HCV infection treated with interferon-free or interferon-based regimens.
View Article and Find Full Text PDFJ Formos Med Assoc
December 2024
Huang Cheng Kuo Clinic, Taiwan. Electronic address:
The COVID-19 pandemic has had a profound impact globally, particularly in high-risk populations such as those with underlying health conditions. In response to the evolving pandemic landscape and the recent surge in confirmed cases in Taiwan, the Taiwan Association of Family Medicine (TAFM) established a consensus on COVID-19 vaccine recommendations for vulnerable groups through a comprehensive literature review, expert panel discussions, and a practice-oriented formulation procedure to develop evidence-based guidance. Its key findings highlight the increased risk of severe COVID-19 outcomes among individuals with disorders such as diabetes, obesity, chronic kidney disease, cardiovascular disease, and respiratory illness.
View Article and Find Full Text PDFJ Sex Med
December 2024
Department of Urology, National Taiwan University Hospital and College of Medicine, Zhongzheng Dist., Taipei City 100225, Taiwan (R.O.C.).
Background: Pelvic arterial (PLA) stenosis is associated with arterial insufficiency of the penis and erectile dysfunction (ED), but the effect of different severities of PLA stenosis on ED remains unclear.
Aim: To investigate how different severities of PLA stenosis affect erectile function.
Methods: We included patients who visited our clinic for ED and underwent computed tomography angiography (CTA) and dynamic duplex sonography (DUS).
J Formos Med Assoc
December 2024
Division of Thoracic Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Background/purpose: This multi-institutional study was aimed to analyze prognostic factors of completely resected early stage thymoma.
Methods: Patients with surgically treated early stage thymoma between 1988 and 2019 were enrolled. Statistical associations were evaluated using the χ test, Fisher's exact test, and Student's t-test.
Aging (Albany NY)
December 2024
Department of Chinese Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Niaosong District, Kaohsiung 833, Taiwan.
Objective: The study aimed to assess the clinical effects of employing the Huangqi formula (Eefooton; EFT) for chronic kidney disease (CKD) treatment. A narrative literature review was undertaken to elucidate the specific ingredients of EFT and their potential impact on renal health.
Methods: A retrospective observational study investigated EFT treatment in outpatients with stable CKD (stages 3B to 5) from March 2019 to March 2021.
Biologics
December 2024
Graduate Institute of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan.
Biomacromolecules
December 2024
Division of Molecular Science, Graduate School of Science and Technology, Gunma University, 1-5-1 Tenjin, Kiryu 376-8515, Gunma, Japan.
We investigated the fracture behavior of cellulose nanofiber (CNF)-reinforced poly(vinyl alcohol) (PVA) hydrogels cross-linked with borax and the effect of freeze-thaw (FT) cycles on it. The CNF/PVA/Borax hydrogel not subjected to FT achieved a fracture energy of 5.8 kJ m and a dissipative length of 2.
View Article and Find Full Text PDFSTAR Protoc
December 2024
Department of Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan. Electronic address:
2-deoxy-D-glucose (2DG) is a glucose analog converted to 2-deoxy-D-glucose-6-phosphate (2DG-6P) by hexokinase in glycolysis. While 2DG commonly measures glucose uptake, 2DG-6P detects glucose utilization. Here, we present a protocol to measure glucose utilization in various tissues after entering a mouse's body using radiolabeled 2DG.
View Article and Find Full Text PDFJ Palliat Med
December 2024
Department of Family Medicine and Division of Geriatrics and Gerontology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Misconceptions of and cultural differences in aging influence older adults' medical decision-making self-efficacy and engagement in advance care planning (ACP). This study aims to investigate the association between current medical decision-making participation self-efficacy and ACP engagement among older individuals receiving home-based medical care (HBMC) in Taiwan. Baseline data analysis of a nationwide cohort study.
View Article and Find Full Text PDFBioresour Technol
December 2024
Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. Electronic address:
Aquaculture waste and carbon dioxide (CO) are a global concern. Sarcodia suiae cultivated in outdoor photobioreactors (PBRs) using shrimp aquaculture wastewater and CO from biogas demonstrates significant benefits. It boosted biomass by 18.
View Article and Find Full Text PDFJ Toxicol Environ Health A
December 2024
Department of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan.
Sex ratio at birth (SRB) is a simple, noninvasive way to monitor the reproductive health of a population. Apparently only a few studies have assessed the relationship between ambient air pollution and SRBs. The studies that investigated this relationship have yielded inconsistent results.
View Article and Find Full Text PDFAnticancer Res
December 2024
Division of Colon and Rectal Surgery, Department of Surgery, Chang-Gung Memorial Hospital Kaohsiung Medical Center, Chang-Gung University College of Medicine, Kaohsiung, Taiwan, R.O.C.
Cell Transplant
December 2024
Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan.