Trainee experience in virtual reality simulation in orbital surgery.

Purpose: To demonstrate the role of Virtual Reality (VR) in orbital surgery as an educational tool for surgical trainees.

Methods: A single-center prospective study was conducted from February 2021 to April 2023. Pre-operative magnetic resonance imaging and computed tomography scans were used to create patient-specific VR models of the orbit using ImmersiveTouch Software.

Elastic Fibers in Orbital Septum.

Purpose: To examine microscopically the nature of the elastic fibers of the orbital septum in elderly specimens in comparison with the young specimen.

Materials And Methods: Histological evaluation of 15 tissues of the orbital septa from upper eyelid (8 right, 7 left) from 11 Japanese cadavers (age range: 36-94 years old, average: 75.5) was performed.

Primary Orbital Conjunctival Cyst Associated With the Inferior Rectus Muscle.

Primary simple conjunctival cysts are congenital, non-neoplastic, fluid-filled lesions lined by non-keratinizing squamous epithelium without dermal appendages. They are usually located in the anterior superonasal or superotemporal orbit and are typically managed with complete surgical excision. A 69-year-old woman presented with a 10-month history of diplopia and a 2-week history of right lower eyelid swelling.

Orbital Septum in Lateral Canthus.

Purpose: To disclose the precise attachment site of the orbital septum in the lateral canthus.

Methods: Nine specimens of 7 Japanese cadavers aged 66 to 85 years at death were included. The attachment site of the orbital septum in the lateral canthus was grossly dissected.

Clinical outcomes and prognostic factors in patients with nasolacrimal duct obstruction or stenosis using dacryoendoscopy.

Objective: To evaluate the effectiveness of dacryoendoscopic-assisted laser dacryoplasty with silicone intubation (DLDI) for the management of nasolacrimal duct obstruction (NLDO) or stenosis, and to identify the factors associated with DLDI failure.

Methods And Analysis: This study was designed as a prospective, single-centre cohort study. Patients with NLDO or stenosis who underwent DLDI from December 2019 to December 2021 at Tianjin Eye Hospital were considered for enrolment.

The importance of simultaneous oculoplastic surgery in quality of life related to vision in surgical resection of large vestibular schwannomas.

Objectives: Facial nerve palsy is one of the most important complications of vestibular schwannoma resection. When VII cranial nerve is damaged, ocular complications might appear, impacting patient´s quality of life. Therefore, standardized eye care must be a priority.

[Expert consensus on the diagnosis and treatment of immunoglobulin-G4 related ophthalmic disease (2024 edition)].

Immunoglobulin-G4 related ophthalmic disease (IgG4-ROD) is an immune-mediated fibroin flammatory condition characterized by ocular mass lesions and elevated plasma IgG4 level. Since all the ocular tissues can be involved, and it can be accompanied by multiple organ and systemic diseases, the diagnosis and treatment require multidisciplinary collaboration. The Oculoplastic and Orbital Disease Group of Chinese Ophthalmological Society of Chinese Medical Association and the Chinese Rheumatology Association convened experts in ophthalmology, and rheumatology and immunology, and formulated "Expert consensus on the diagnosis and treatment of immunoglobulin-G4 related ophthalmic disease (2024 edition)" for the diagnosis and treatment of IgG4-ROD based on domestic and international studies and experience.

Reconstructive Techniques Following Malignant Eyelid Tumour Excision-Our Experience.

: Malignant eyelid tumours present a considerable challenge in the field of ophthalmic oncology, necessitating a combination of precision oncological care and meticulous reconstruction to ensure the preservation of eyelid functionality and the maintenance of facial aesthetics. : This study presents a review of the outcomes of 167 patients who underwent eyelid reconstruction following the excision of primary non-melanocytic malignant tumours. The choice of reconstruction technique was dependent on a number of factors, including the stage of the tumour, its location, and the characteristics of the patient.

Teprotumumab for the Treatment of Thyroid Eye Disease: Why Should We Keep Our Eyes "Wide Open"?-A Clinical and Pharmacovigilance Point of View.

Thyroid eye disease (TED) treatment has been recently revolutionized with the approval of teprotumumab, a targeted insulin growth factor 1 receptor (IGF1R) inhibitor. To date, teprotumumab is the only FDA-approved drug for treating TED. In this article, we would like to temper the current enthusiasm around IGF1R inhibitors.

Immunohistochemistry-Assisted Mohs Surgery for Invasive Eyelid and Periorbital Cutaneous Melanoma.

Background: Prior studies describe wide local excision and "slow Mohs" outcomes for periocular melanoma. Mohs micrographic surgery (MMS) with immunohistochemistry maximizes tissue preservation and offers same-day comprehensive margin evaluation, which facilitates expedited repair, and coordination of oculoplastic reconstruction when necessary.

Objective: To describe oncologic and reconstructive outcomes of invasive periocular cutaneous melanoma treated with immunohistochemistry-assisted MMS.

The efficacy of a netilmicin/dexamethasone gel combination in the treatment of posterior blepharitis in moderate-severe dry eye patients.

Purpose: To evaluate the safety and efficacy of netilmicin/dexamethasone combination in the treatment of meibomian gland dysfunction (MGD)-associated posterior blepharitis.

Methods: In this prospective and controlled study were enrolled 40 patients with MGD and symptoms of dry eye disease. Two groups were established: 20 patients (group 1) received netilmicin 3 mg/ml and dexamethasone 1 mg/ml eye gel, whereas in group 2 (20 patients) received vehicle for 15 days.

Comparison between local-made and imported porous polyethylene orbital implant: a randomized controlled equivalence trial and multicenter study.

Aim: To compare the exposure rate, infection rate, percentage of enhancement, and success rate between Medpor and the three-dimensional printed polyethylene (3DP-PE) orbital implant in a preliminary report.

Methods: This prospective, randomized, equivalence, controlled trial was conducted at two institutes. The equivalent margin was ±10%.

Calcium Hydroxyapatite as a Co-adjuvant Treatment Option in a Patient With Morphea: A Report of a Case With a One-Year Follow-Up.

Morphea, or localized scleroderma, is a chronic inflammatory condition that unequivocally affects the dermis and subcutaneous connective tissue. It undeniably causes significant disfigurement in approximately half of patients, profoundly impacting their self-esteem. The available treatment options include corticosteroids (taken orally or administered subcutaneously), phototherapy, CO fractional laser treatment, and biologically mediated medications.

Retinal Vasculopathy and Choroiditis after Pegcetacoplan Injection: Clinicopathologic Support for a Drug Hypersensitivity Reaction.

Purpose: To report the detailed histopathology of 2 enucleated eyes from 2 patients who developed severe visual loss associated with retinal hemorrhages, vessel sheathing, and vascular nonperfusion after administration of an initial dose of intravitreal pegcetacoplan, and propose, with supportive histopathology, the pathogenesis of the clinical syndrome previously termed hemorrhagic occlusive retinal vasculitis.

Design: Case series.

Subjects: Two enucleated eyes from 2 patients treated with intravitreal pegcetacoplan.

Immediate Postoperative Difference of Eyelid Height Based on Intraoperative Measurement of Levator Aponeurosis Advancement in Patients with Unilateral Ptosis.

Purpose: To determine the relationship between marginal reflex distance (MRD-1) outcomes and the distance of levator aponeurosis advancement.

Methods: This retrospective observational study included patients with acquired unilateral aponeurotic ptosis, who underwent small-incision anterior levator advancement. The distance of levator advancement, and intra-operative MRD-1 in the sitting position, were analyzed to determine a correlation between the two.

Clinical performance of a novel and rapid bioassay for detection of thyroid-stimulating immunoglobulins in Graves' orbitopathy patients: a comparison with two commonly used immunoassays.

Background: For the selective detection of thyroid-stimulating hormone receptor antibodies with stimulating properties (thyroid-stimulating immunoglobulins; TSI), a novel and rapid bioassay (Turbo TSI) has been introduced. We evaluate the clinical performance of Turbo TSI in Graves' orbitopathy (GO) patients and compare it to a bridge-based TSI binding immunoassay and third generation TSH-R-binding inhibitory immunoglobulins (TBII) assay. Also, we investigate the association of Turbo TSI and TBII measurements with GO activity and severity, as well as response to intravenous methylprednisolone (IVMP), and compare results to previous findings on the bridge-based TSI binding immunoassay.

Lymphatic Channel Distribution in Comparison With Blood Vessels in the Upper Eyelid.

Purpose: To examine microscopically the distribution of the lymphatic channels in comparison with the blood vessels in the upper eyelid.

Methods: Central sagittal sections of 13 upper eyelids (8 right, 5 left) from 11 Japanese cadavers, aged 36 to 87 years old (average age: 66.6 years), were histologically examined.

Thickness of the Orbital Septum in Comparison to Periorbita and Periosteum.

Purpose: To examine the thickness of the orbital septum in comparison to that of the periorbita and the periosteum of the frontal bone.

Methods: Histological evaluation of 11 tissues around the upper arcus marginalis, including the orbital septum, periorbita, and periosteum of the frontal bone (5 right, 6 left) from 11 Japanese cadavers (age range: 63-91-year-old, average: 77.1, male: 5 cases and female: 6 cases) was performed.

The use of trypan blue to enhance intraoperative visualization during congenital lacrimal fistulectomy.

We describe the use of trypan blue stain to enhance visualization of the tract of the fistula during congenital lacrimal fistulectomy in a 9-year-old boy. This video demonstrates the surgical technique and the intraoperative finding of deep branching of the fistula in this case. We discuss alternative methods of improving delineation of the fistula's path during congenital lacrimal fistulectomy.