409 results match your criteria: "Hyperthyroidism Thyroid Storm and Graves Disease"
Spontaneous Unilateral Carotid Dissection: A Case Report of a Rare Complication in a Patient With Graves' Disease.
Cureus
October 2024
Department of Endocrinology and Metabolism, University of Antioquia, Hospital San Vicente Foundation, Medellín, COL.
Article Synopsis
Liver Dysfunction in Hyperthyroidism.
Hepat Med
November 2024
Division of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Article Synopsis
Iodine and Hyperthyroidism: A Double-Edged Sword.
Endocr Pract
November 2024
Section of Endocrinology, Diabetes, Nutrition, and Weight Management, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts. Electronic address:
Article Synopsis
Preoperative Preparation in Hyperthyroidism and Surgery in the Hyperthyroid State.
Sisli Etfal Hastan Tip Bul
September 2024
Department of General Surgery, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Article Synopsis
Pediatric Graves' Disease: Surgical Interventions in a Single Institution - A Comprehensive Case Series.
Indian J Otolaryngol Head Neck Surg
October 2024
Division of Oncology Surgery, Department of Surgery, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Diponegoro Street Number 71, Jakarta, 10430 Indonesia.
Article Synopsis
- Graves' disease is the main cause of hyperthyroidism in kids and teens, but data on how it affects Indonesian youth is scarce, making diagnosis and treatment difficult.
- In a study of five pediatric GD patients, all showed symptoms like neck lumps and had low TSH and high FT4 levels before surgery; they all underwent total thyroidectomy, with some facing complications like hoarseness and hypocalcemia.
- While total thyroidectomy can be an effective treatment, managing the surgery risks and monitoring for complications afterward is crucial for better patient outcomes.
Unusual Presentations of Thyrotoxic Tricuspid and Mitral Regurgitations in 62 Adults: A Systematic Review of Case Reports with In-depth Pathophysiological Review.
Eur Cardiol
July 2024
Department of Internal Medicine, Faculty of Medicine, Dr Hasan Sadikin General Hospital, Universitas Padjadjaran Bandung, West Java, Indonesia.
Article Synopsis
- Thyrotoxicosis is linked to cardiovascular issues and may lead to conditions like tricuspid regurgitation (TR) and mitral regurgitation (MR), though research on these specific heart problems is still limited.
- A systematic review analyzed 57 case reports of 62 predominantly female patients (average age 45.77 years) with thyrotoxicosis, revealing improvements in heart conditions like TR, MR, heart failure (HF), and pulmonary hypertension (PH) after treatment.
- The study concludes that treating hyperthyroidism can lead to significant clinical recovery in heart issues within six months, driven by both direct effects of thyroid hormones and other related factors.
Generation of a mouse model of thyroid storm and preliminary investigation of the therapeutic effects of ghrelin.
BMC Endocr Disord
August 2024
First Department of Medicine, Wakayama Medical University, Wakayama, Japan.
Article Synopsis
- Researchers developed a mouse model of thyroid storm (TS) using triiodothyronine and lipopolysaccharide to better understand the condition and test treatments like ghrelin.
- The TS mouse model showed increased serum IL-6 levels, indicating hypercytokinemia, and had a survival rate of about 30% without treatment, but improved significantly to 66.7% with ghrelin administration.
- This study provides insights into TS mechanisms and potential therapeutic strategies, marking progress towards effective treatments for this life-threatening condition.
From routine to rescue: Thyroidectomy for life-threatening thyrotoxicosis.
World J Surg
December 2024
Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Article Synopsis
A Lower Prevalence of Central Nervous System and Higher Prevalence of Cardiac Symptoms Characterises Indian Patients with Thyrotoxic Storm: A Retrospective Analysis.
Indian J Endocrinol Metab
June 2024
Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Article Synopsis
- Thyroid storm is a rare but serious condition resulting from excessive thyroid hormones, with a mortality rate of 10%, and the study focused on understanding its characteristics among inpatients in India from 2004 to 2020.
- Out of 35 patients studied, a majority were women, the most common cause was Graves' disease, and many presented with cardiovascular and gastrointestinal issues, while only about 42% showed central nervous system symptoms.
- Nearly half of the patients had no prior diagnosis of thyroid issues, and the study suggested that the Japanese Thyroid Association's diagnostic criteria might differ from the Burch-Wartofsky score due to the lack of CNS symptoms in Indian patients.
Assessing the relationship between psoriasis and thyroid dysfunction through two sample MR analysis.
Arch Dermatol Res
June 2024
Institute of Dermatology, Guangzhou Medical University, Guangzhou, China.
Article Synopsis
- The study investigates the relationship between psoriasis and thyroid dysfunction (hyperthyroidism/hypothyroidism) using Mendelian randomization methods due to inconsistent findings in previous research.
- The analysis of genetic data from various sources found no overall correlation between psoriasis and thyroid issues, but noted certain types of psoriasis (vulgar and guttate) were linked to hypothyroidism and Graves' disease.
- The conclusion emphasizes that while no direct association was found between psoriasis and thyroid dysfunction, awareness of potential risks, such as hypothyroidism and Graves' disease, is essential in clinical practice for patients with certain forms of psoriasis.
The Two-Year Results of Using Radiofrequency Ablation as a Novel Treatment for Persistent or Relapsed Graves' Disease: A Prospective Study.
Thyroid
August 2024
Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
Article Synopsis
- Graves' disease is the leading cause of hyperthyroidism, and while antithyroid drugs are the first-line treatment, many patients experience relapses after stopping these medications, prompting the need for alternative treatments like radiofrequency ablation (RFA).
- A study involving 30 patients with persistent Graves' disease who underwent RFA found a 60% remission rate at 12 months and 56.7% at 24 months, with total thyroid volume as a key factor affecting relapse risk.
- The study highlighted that among patients who relapsed after RFA, most required a lower dose of antithyroid drugs than before the procedure, and RFA achieved full remission in patients with smaller thyroid volumes (<20 mL
Thyroid storm after coronavirus disease 2019 mRNA vaccination in a patient with a history of Graves' disease after coronavirus disease 2019 infection.
BMJ Case Rep
June 2024
Endocrinology and Metabolism, Dokkyo Medical University, Shimotsuga-gun, Japan.
Article Synopsis
- - The case describes a patient who potentially developed Graves' disease after being infected with COVID-19.
- - It suggests that the COVID-19 vaccination may have worsened the patient's condition, leading to a thyroid storm.
- - While it's difficult to prove a direct link between the vaccine and the thyroid disease onset, the combination of prior COVID-19 infection and vaccination could have played a role in triggering the Graves' disease.
Perioperative Care of a Child With Hyperthyroidism.
J Med Cases
April 2024
The Ohio State University College of Medicine, Columbus, OH, USA.
Article Synopsis
- A 3-year-old child with Graves' disease required a total thyroidectomy after suffering from severe symptoms and TS, which could not be controlled with medication due to adverse reactions.
- Following surgery, the child's condition improved, and he was discharged with levothyroxine therapy, highlighting the need for awareness and management of TS in pediatric patients who do not respond to standard treatments.
Plasmapheresis in thyrotoxicosis: a single-center case series.
J Med Case Rep
March 2024
Department of Endocrinology-Diabetology and Nutrition, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital Center, University of Mohammed 1st, 4806, 60049, Oujda, Morocco.
Article Synopsis
- Plasmapheresis is explored as a therapy for hyperthyroidism, especially in severe cases like thyroid storm, where it helps quickly reduce thyroid hormone levels and antibodies.
- The study showcases three young African patients with Graves' disease who experienced complications from traditional treatments and successfully underwent plasmapheresis, which stabilized their condition for surgery.
- The findings suggest that while standard treatments are often effective, plasmapheresis can be a safe and efficient alternative for patients unable to tolerate conventional medications before surgery.
Prospective Multicenter Registry-Based Study on Thyroid Storm: The Guidelines for Management From Japan Are Useful.
J Clin Endocrinol Metab
December 2024
First Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, Japan.
Context: The mortality rate in thyroid storm (TS) has been reported to be higher than 10%.
Objective: We aimed to evaluate the effectiveness of the 2016 guidelines for the management of TS proposed by the Japan Thyroid Association and Japan Endocrine Society.
Methods: In this prospective multicenter registry-based study, patients with new-onset TS were registered in the Research Electronic Data Capture (REDCap), a secure web platform.
A Case of Acute Neurologic Deficit and Hypoglycemia in the Setting of Thyroid Storm and Diabetic Ketoacidosis: A New Clinical Scenario.
Korean J Fam Med
January 2024
I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
The simultaneous development of diabetic ketoacidosis (DKA) and thyroid storm (TS) is a rare but potentially lifethreatening condition that requires immediate and targeted treatment. However, their combined diagnosis poses a serious challenge because of the similarities between their clinical manifestations. To date, only a few dozen cases have been described; most of which have been linked to the progression of thyrotoxicosis or uncontrolled hyperglycemia as contributing factors.
View Article and Find Full Text PDFComplications related to thyroidectomy among patients with hyperthyroidism: Exploring the potential for ambulatory surgery.
Head Neck
May 2024
Department of Otorhinolaryngology - Head and Neck Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA.
Article Synopsis
- A study investigated the safety of outpatient total thyroidectomy in 183 patients with hyperthyroidism over a seven-year period, focusing on complications and postoperative outcomes.
- Results showed no instances of thyroid storm, with low rates of complications like vocal nerve damage and hypocalcemia, along with minimal emergency department visits and no readmissions.
- The findings suggest that outpatient surgery could be a viable option for hyperthyroid patients, highlighting the need for further research to understand factors influencing postoperative risks.
Autoimmune Implications in a Patient with Graves' Hyperthyroidism, Pre-eclampsia with Severe Features, and Primary Aldosteronism.
Medicina (Kaunas)
January 2024
Department of Internal Medicine, Texas Tech University Health Sciences Center, Amarillo, TX 79106, USA.
Article Synopsis
Thyroid storm triggered by thyroid nodule fine needle aspiration biopsy: a case report.
AME Case Rep
December 2023
Division of Endocrinology, University of Miami School of Medicine, Miami, FL, USA.
Background: Thyroid storm is a potentially fatal thyrotoxicosis triggered by an event, such as manipulation of the thyroid gland, acute iodine load, trauma, or infection. Prior to deciding on fine needle aspiration (FNA) biopsy, patients who have been diagnosed with hyperthyroidism or low thyroid stimulating hormone and multinodular goiter (MNG) should be imaged via radionuclide thyroid scan.
Case Description: We present a case of a 62-year-old female patient with history of MNG, who had thyrotoxicosis on presentation due to medication noncompliance and was found to have Graves' disease.
Perchlorates in the treatment of hyperthyroidism and thyrotoxicosis: a comprehensive review.
Endocrine
July 2024
Interdisciplinary Department of Medicine, School of Medicine, University of Bari "Aldo Moro", Bari, 70124, Italy.
Article Synopsis
- * A systematic review was conducted to assess current guidelines and clinical trials related to the effectiveness and safety of perchlorates in various forms of hyperthyroidism, including Graves' disease and pregnancy-related issues.
- * Despite limitations in existing studies, perchlorates could be regarded as a second-line treatment option for iodine-related hyperthyroidism and thyroid storm, especially when other treatments are not viable.
Graves' Disease Exacerbation with Impending Thyroid Storm After SARS-CoV-2 Infection: A Case Report.
Am J Case Rep
January 2024
Department of Internal Medicine, Charleston Area Medical Center (CAMC), Charleston, WV, USA.
Article Synopsis
Therapeutic Plasma Exchange in Refractory Atrial Fibrillation Secondary to a Thyroid Storm.
Cureus
November 2023
Obesity, Endocrine, and Metabolism Centre, King Fahad Medical City, Riyadh, SAU.
Article Synopsis
Advancing Preoperative Strategies for Thyroidectomy in Graves' Disease: A Narrative Review.
Cureus
November 2023
Anatomical Sciences, St. George's University School of Medicine, Saint George's, GRD.
Article Synopsis
New-Onset Graves' Disease With Thyroid Storm After COVID-19 Infection.
Cureus
October 2023
Endocrinology, Beaumont Hospital, Farmington Hills, Farmington Hills, USA.
Article Synopsis
Therapeutic Plasma Exchange as a Bridging Therapy for the Definitive Treatment of a Patient with Graves' Disease and Methimazole-Induced Liver Injury.
Int J Endocrinol Metab
July 2023
Division of Surgical Oncology, Department of Surgery, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia.
Introduction: Graves' disease (GD) is an autoimmune condition affecting the thyroid gland. The aim of treating GD is to control the symptoms of hyperthyroidism and achieve long-term remission. Antithyroid drugs (ATDs) are the medications of choice among newly-diagnosed GD patients as they are easy to be delivered and cause remission in more than 50% of patients.
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