169 results match your criteria: "Hyogo Prefectural Awaji Medical Center.[Affiliation]"

Background: Atrial infarction is a complication of myocardial infarction with ventricular infarction; however, isolated atrial infarction (IAI) has rarely been reported. Herein, we report a case of IAI associated with sick sinus syndrome and atrial fibrillation (AF).

Case Summary: An 83-year-old woman was brought to the emergency department with a complaint of general malaise.

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Background & Aims: In older patients undergoing cardiac surgery, physical function is a critical determinant of postoperative outcomes. Beta-hydroxy-beta-methylbutyrate (HMB) supplementation has been shown to promote muscle protein anabolism and inhibit catabolism, thereby preventing muscle weakness. However, its efficacy in older patients undergoing cardiac surgery remains unknown.

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Background: Atrial standstill is characterized by the absence of atrial activity. We report a case of a patient with extensive atrial fibrosis who underwent electrophysiologic study (EPS) and electroanatomical mapping (EAM) to identify surviving atrial sites amenable for pacemaker lead implantation.

Case Summary: A 72-year-old man with persistent atrial fibrillation (AF) and atrial functional mitral regurgitation/tricuspid regurgitation (MR/TR) underwent a Cox-Maze surgery, mitral and tricuspid valve repair, and biatrial plication.

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Primary tracheal diffuse large B-cell lymphoma (DLBCL) is a rare, aggressive, but potentially curable malignancy that is difficult to diagnose and treat. We herein report a 93-year-old Japanese man diagnosed with primary tracheal DLBCL after presenting with progressive dyspnea due to severe upper tracheal stenosis during follow-up for pulmonary amyloidosis. Following the diagnosis, the patient was treated with corticosteroids, followed by R-CHOP chemotherapy, resulting in a therapeutic response.

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Background: Patients with heart failure exhibiting low systolic blood pressure (SBP) have a poor prognosis. Sacubitril/valsartan reduces cardiovascular events; however, its use in patients with low SBP has not been fully examined. Therefore, in this study, we aimed to investigate the association between baseline SBP and adverse events (AEs) in patients starting sacubitril/valsartan therapy using data from a real-world registry in Japan.

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Article Synopsis
  • - The study focuses on the increasing detection of wild-type transthyretin (ATTR) amyloidosis and evaluates the effectiveness of Tc-labeled pyrophosphate (Tc-PYP) scintigraphy for diagnosing ATTR cardiac amyloidosis in patients across Japan from 2018 to 2022.
  • - Out of 180 patients, 135 were analyzed, with 62 testing positive for Tc-PYP; researchers developed a scoring system based on five clinical factors to predict positivity, revealing that a higher score correlates with a greater likelihood of positive results.
  • - The study concludes that combining commonly available clinical data can significantly enhance the pretest prediction accuracy for Tc-PYP scintigraphy, aiding clinicians in the early diagnosis of ATTR amyloidosis
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Background: A novel cardioprotective drug, vericiguat, reduces the risk of cardiovascular mortality for patients already on guideline-directed medical therapy. However, the effect of vericiguat on left ventricular (LV) reverse remodeling in patients with reduced LV ejection fraction (LVEF) with or without guideline-directed medical therapy, known as quadruple medical therapy, remains undetermined.

Methods And Results: This study comprised 73 heart failure (HF) patients with reduced LVEF (<45%) from 5 institutions in Japan.

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Article Synopsis
  • Stage B heart failure (HF) involves structural heart disease without symptoms, and identifying risk in these patients is complex but crucial for early intervention.
  • A study of 1,646 heart failure patients established a scoring system called BEEAF to categorize stage B HF patients into low, moderate, and high-risk groups based on specific health indicators.
  • The results indicated that higher risk levels predicted worse outcomes, with high-risk stage B patients faring similarly to those in stage C HF.
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  • The study aimed to develop guidelines for antibiotic use during tooth extractions in cancer patients on denosumab, as there's a risk of medication-related osteonecrosis of the jaw (MRONJ).
  • It analyzed 68 cancer patients' antibiotic administration practices and their correlation with MRONJ after tooth extractions over a 10-year period.
  • Results showed a lot of inconsistency in antibiotic usage among hospitals, with amoxicillin being the most common; however, no significant link between MRONJ occurrence and the dosage or duration of amoxicillin was identified, suggesting a single preoperative dose may be sufficient.
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  • The study aimed to compare the effectiveness of optical frequency domain imaging (OFDI) versus intravascular ultrasound (IVUS) in guiding percutaneous coronary intervention (PCI) for patients with acute coronary syndrome (ACS).
  • PCI was successful in all cases, with fewer complications observed in the OFDI group, and better post-procedure coronary flow.
  • Both methods resulted in similar in-stent minimum lumen area at 8 months, suggesting that OFDI guidance is as safe and effective as IVUS guidance for ACS patients.
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Purpose: To investigate the midterm stent patency and patient prognosis after stenting for superior mesenteric artery malperfusion complicating with acute aortic dissection.

Material And Methods: Thirteen patients who underwent branch vessel stenting for superior mesenteric artery malperfusion between 2011 and 2021 in six institutions were retrospectively reviewed. By comparing pre- and postoperative computed tomography scans in the same plane, the length of the stent implanted in the superior mesenteric artery and the stent-to-vessel diameter ratio were measured.

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  • A study was conducted to evaluate the effectiveness of a rapid urease test (Swab-RUT) for detecting Helicobacter pylori (H. pylori) compared to traditional methods like Forceps-RUT and the C-urea breath test (UBT).
  • The research involved 94 participants across four institutions, where both Swab-RUT and Forceps-RUT were performed during esophagogastroduodenoscopy; UBT was used to confirm H. pylori status.
  • Results showed Swab-RUT had high sensitivity (93.3%), specificity (92.2%), and accuracy (92.6%), indicating it’s a reliable method for detecting H. pylori infections without complications.
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Background: Combining morphological and physiological evaluations might improve the risk stratification of patients who undergo percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) culprit lesions.

Aims: We aimed to investigate the clinical utility of morphofunctional evaluation after PCI for identifying ACS patients with increased risk of subsequent clinical events.

Methods: We retrospectively studied 298 consecutive ACS patients who had undergone optical coherence tomography (OCT)-guided PCI.

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  • Tricuspid annular disjunction (TAD) is a rare heart condition often linked with mitral annular disjunction (MAD), but it primarily leads to tricuspid regurgitation (TR) rather than mitral regurgitation (MR).
  • A case involving a 63-year-old woman revealed severe TR caused by TAD, characterized by a redundant tricuspid valve leaflet, which required surgical treatment despite initial MR being detected.
  • The report highlights the growing recognition of TAD's impact on TR, the gradual nature of its progression compared to MAD, and the diagnostic difficulties that underline the need for better imaging techniques for effective management.
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Objectives: We introduced the critical pathway (CP) for follow-up on patients with postoperative lung cancer to the staff of the Hyogo Prefectural Awaji Medical Center and regional medical institutions in Japan, in 2010.

Methods And Results: We raised awareness within our hospital and collaborating medical institutes and trained our staff on the CP before introducing it. From May 2013 through October 2023, lung cancer surgery was performed on 460 patients.

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Side branch embolization before endovascular abdominal aortic aneurysm repair to prevent type II endoleak: A prospective multicenter study.

Diagn Interv Imaging

September 2024

Department of Diagnostic and Interventional Radiology, Kobe University Hospital, Kobe, 7-5-2 Kusunokicho, Chuo Ward, Kobe City, Hyogo 650-0017, Japan.

Purpose: The purpose of the study was to evaluate the efficacy and safety of pre-emptive transcatheter arterial embolization (P-TAE) of aortic side branches to prevent type II endoleak in patients with abdominal aortic aneurysm after endovascular abdominal aneurysm repair (EVAR).

Materials And Methods: This multicenter, prospective, single-arm trial enrolled 100 patients with abdominal aortic aneurysm from nine hospitals between 2018 and 2021. There were 85 men and 15 women, with a mean age of 79.

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Article Synopsis
  • The study aimed to assess the safety and effectiveness of pre-emptive transcatheter arterial embolization (P-TAE) for aortic side branches to prevent Type 2 endoleaks (EL2) before endovascular aneurysm repair (EVAR) using the Excluder stent-graft system.
  • A total of 80 patients participated, with successful P-TAE performed on 81.6% of aortic side branches, leading to a 25.7% incidence of EL2 at 6 months and significant aneurysmal sac shrinkage in a portion of patients.
  • The findings suggest that P-TAE is a safe and effective approach, aiding in early aneurysmal sac shrinkage and
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  • This study looked at early signs of pancreatic ductal adenocarcinoma (PDAC), specifically focal parenchymal atrophy and main pancreatic duct (MPD) dilatation, to better understand their progression over time.
  • Out of 1,832 patients with PDAC, 320 had CT scans prior to diagnosis, and 47.8% showed suspicious findings, with focal parenchymal atrophy being the earliest sign, detected an average of 2.7 years before diagnosis.
  • The research highlighted that focal parenchymal atrophy frequently appeared before MPD dilatation, with both findings progressing before diagnosis, suggesting potential markers for early detection in patients.
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Background: Early detection and intervention for preclinical heart failure (HF) are crucial for restraining the potential increase in patients with HF. Thus, we designed and conducted a single-center retrospective cohort study to confirm the efficacy of B-type natriuretic peptide (BNP) for the early detection of preclinical HF in a primary care setting.

Methods and results: We investigated 477 patients with no prior diagnosis of HF who were under the care of general practitioners.

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Article Synopsis
  • A study investigated the effects of continuing steroid therapy beyond 3 years for patients with autoimmune pancreatitis who maintained remission during an initial 3-year period.
  • Out of 211 patients, those who continued steroid therapy had a lower relapse rate compared to those who stopped, but they also faced a higher risk of developing macrovascular complications.
  • The findings suggest that while ongoing steroid use may prevent relapse, it also raises concerns about serious long-term health issues, particularly for patients with renal involvement.
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