3,163 results match your criteria: "Hymenoptera Stings"
Hymenoptera venom allergy in children.
Ital J Pediatr
December 2024
Department of Health Sciences, University of Florence, Florence, 50139, Italy.
From a taxonomic point of view, Hymenoptera are subclassified into families: Apidae, including honeybees (Apis mellifera) and bumblebees (Bombus), and Vespidae, which, in turn, are divided into the subfamilies of Vespinae (wasps, including hornets, vespules, dolichovespules) and Polistinae (paper wasp). Hypersensitivity to Hymenoptera venom can be linked to immunological (IgE-mediated or non-IgE-mediated) and non-immunological mechanisms. Reactions are classified into local reactions, large local reactions, systemic reactions, toxic reactions, and unusual reactions.
View Article and Find Full Text PDFCorneal bee sting injury: a clinical conundrum.
BMJ Case Rep
December 2024
Shantilal Shanghvi Cornea Institute (SSCI), L V Prasad Eye Institute(LVPEI), Kode Venkatadri Chowdary(KVC) Campus, Vijayawada, Andhra Pradesh, India
This study outlines the clinical features and comprehensive management of three cases of corneal injury by a bee sting. The stinger removal was attempted, and in two cases, the stinger was successfully removed. In one case, a portion of the stinger broke and was left in situ without inciting any further inflammation.
View Article and Find Full Text PDFComponent-Based Assessment of the Main Allergens in Honeybee Venom in a Spanish Allergic Population.
J Investig Allergol Clin Immunol
December 2024
Inmunotek Laboratories, Madrid, Spain.
Africanized honeybee venom ( promotes human complement activation split products storm.
Front Immunol
November 2024
Immunochemistry Laboratory, Butantan Institute, São Paulo, Brazil.
Article Synopsis
Activation of mouse skin mast cells and cutaneous afferent C-fiber subtypes by bee venom.
Neurosci Lett
January 2025
Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Cir, Baltimore, MD 21224, USA. Electronic address:
In mammals, many Hymenopteran stings are characterized by pain, redness, and swelling - three manifestations consistent with nociceptive nerve fiber activation. The effect of a Western honeybee (Apis mellifera) venom on the activation of sensory C-fibers in mouse skin was studied using an innervated isolated mouse skin preparation that allows for intra-arterial delivery of chemicals to the nerve terminals in the skin. Our data show that honeybee venom stimulated mouse cutaneous nociceptive-like C-fibers, with an intensity (action potential discharge frequency) similar to that seen with a maximally-effective concentration of capsaicin.
View Article and Find Full Text PDFNatural History and Risk Factors of Hymenoptera Venom Allergy in Dogs.
Animals (Basel)
November 2024
Dermatology Unit, Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Article Synopsis
- Hymenoptera is an insect order that includes species like honeybees and wasps, and their venom can cause severe allergic reactions in dogs, similar to humans.
- A study examined the medical histories of 178 dogs stung by these insects to understand risk factors for severe systemic reactions (SSRs), finding that younger dogs, smaller breeds, and those stung in sensitive areas faced higher risks.
- The research highlighted that many dogs with SSRs experienced similar or worse symptoms upon subsequent stings, indicating a strong case for using venom immunotherapy (VIT) for affected dogs.
Comparative Assessment of the Allergenicity of Hyaluronidases from (Pol d 2), (Ves v 2), and Venom (Api m 2).
Toxins (Basel)
November 2024
Center of Allergy and Environment (ZAUM), Technical University of Munich, School of Medicine and Health & Helmholtz Munich, German Research Center for Environmental Health, 85764 Munich, Germany.
Article Synopsis
- * Key allergens evaluated include hyaluronidases from honey bee (Api m 2), European paper wasp (Pol d 2), and yellow jackets (Ves v 2.0101 and Ves v 2.0201), with sensitization rates among patients varying significantly.
- * Results show that individuals primarily sensitized to Api m 2 have minimal cross-reactivity with other venoms, while those sensitized to other allergens may react to Api m 2, emphasizing the importance of identifying the primary allergen for effective
Adaptive trade-offs between vertebrate defence and insect predation drive Amazonian ant venom evolution.
Proc Biol Sci
November 2024
INRAE, UMR Ecologie des forêts de Guyane - EcoFoG (AgroParisTech, CIRAD, CNRS, Université de Guyane, Université des Antilles), Campus Agronomique, BP 316, Kourou Cedex 97379, France.
Article Synopsis
Impact of environmental factors on Apis dorsata (giant Asian honeybee) venom in Bandarawela, Sri Lanka.
Toxicon
December 2024
Department of Immunology, Medical Research Institute, Colombo, Sri Lanka.
Apis dorsata stings are amongst the most frequent insect-stings in Sri Lanka. A. dorsata venom consists of a mixture of components including PLA, melittin, hyaluronidase and apamin.
View Article and Find Full Text PDFA prediction nomogram for mortality in patients following wasp stings: a retrospective study.
Sci Rep
October 2024
Department of Emergency, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, People's Republic of China.
Article Synopsis
Long-term tolerance and efficacy of venom immunotherapy after an episode of Crohn's disease and ankylosing spondylitis after up-dosing.
Allergol Select
October 2024
Department of Dermatology and Allergy, LMU Munich, University Hospital, Munich, Germany.
Hymenoptera stings can cause severe anaphylactic reactions in patients with an underlying Hymenoptera venom allergy (HVA). In such cases, venom immunotherapy (VIT) is a highly effective measure to prevent future anaphylaxis. The management of patients with a clear allergological indication for VIT and contraindications to VIT (e.
View Article and Find Full Text PDFBAX pores facilitate mitochondrial DNA release in wasp sting-induced acute kidney injury.
Int Immunopharmacol
December 2024
Department of Nephrology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China. Electronic address:
The role of B-cell lymphoma 2 (BCL2)-associated X (BAX) macropores in the leakage of mitochondrial DNA (mtDNA) and their impact on acute kidney injury (AKI) has recently been brought to the focus of researchers. This study aimed to explore the relationship between mtDNA leakage and BAX macropores during wasp sting-induced AKI. BAX mitochondrial translocation and macropores opening increased in both in vivo and in vitro models of wasp sting-induced AKI.
View Article and Find Full Text PDFClinical and pathological findings of Africanized bee (Apis mellifera) envenomation in horses.
Toxicon
November 2024
São Paulo State University (UNESP), School of Veterinary Medicine and Animal Science, Department of Veterinary Clinical Science, Botucatu, Brazil. Electronic address:
Africanized crossbred bees (Apis mellifera) originated in Brazil in 1957, and since then, the number of accidents involving humans and animals has significantly increased. Although they are considered clinical emergencies, there are few reports describing the clinical and pathological aspects of bee envenomation in horses. In this context, this report aims to describe the clinical and pathological features of bee toxicity after massive bee envenomation in three horses.
View Article and Find Full Text PDFClinical complications in envenoming by honeybee stings: insights into mechanisms, diagnosis, and pharmacological interventions.
Front Immunol
October 2024
Graduate Program in Tropical Diseases, Botucatu Medical School (FMB), São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Article Synopsis
- Honeybee stings can lead to various health issues, from mild local reactions to serious systemic effects, highlighting it as a public health concern.
- The review discusses the mechanisms of envenoming, different clinical presentations, and the importance of accurate diagnosis for effective treatment.
- It also evaluates new diagnostic technologies and treatment strategies to enhance patient care and outcomes for those affected by honeybee stings.*
Machine-learning based prediction model for acute kidney injury induced by multiple wasp stings.
Toxicon
November 2024
Department of Emergency Medicine, Yichang Central People's Hospital, Yichang, 443003, Hubei, China; Department of Critical Care Medicine, Yichang Central People's Hospital, Yichang, 443003, Hubei, China; The First College of Clinical Medical Science, China Three Gorges University, Yichang, 443003, Hubei, China. Electronic address:
Article Synopsis
- Acute kidney injury (AKI) can occur after multiple wasp stings, leading to serious health issues, but there are limited predictive models specifically for this type of injury.
- * This study developed a machine learning-based prediction model for AKI risk in wasp sting patients, analyzing data from 214 individuals treated at a hospital in China.
- * Important risk factors identified include the number of stings, presence of blood in urine, systemic inflammatory response index, and platelet count, with a nomogram demonstrating good predictive accuracy for assessing AKI risk.
Multiple mechanisms of action of an extremely painful venom.
bioRxiv
September 2024
Department of Biology, Indiana University; Bloomington, IN.
Article Synopsis
- Evolutionary arms races lead to specialized defense mechanisms in predator-prey interactions, with velvet ant venom being a prime example that induces extreme pain in would-be predators.
- Velvet ant venom targets specific pain-sensing pathways in a way that is efficient yet lower in toxicity, making it effective for deterring various vertebrate predators.
- The study revealed that a particular peptide in the venom, Do6a, activates insect nociceptors effectively but does not cause pain in mammals, indicating it may have evolved to specifically affect insect prey.
Monitoring and stopping Hymenoptera venom immunotherapy: Contribution of IgE blocking activity.
J Allergy Clin Immunol Glob
November 2024
Department of Immunology, Centre Hospitalier Universitaire de Limoges, Limoges, France.
Article Synopsis
- Hymenoptera venom allergy significantly affects quality of life, and while allergen immunotherapy (AIT) is effective, predicting its success remains challenging due to a lack of biomarkers.
- This study analyzed patient data from 1985 to 2022 at the University Hospital of Limoges to assess the role of IgE blocking activity as a potential predictor of AIT efficacy against Hymenoptera venom.
- Results indicated that IgE blocking activity did not predict relapse after stopping AIT, but a correlation was found between this activity and IgG antibody levels, suggesting that further research is needed to explore the role of these antibodies in monitoring treatment outcomes.
A lifesaving improvised peritoneal dialysis on a toddler with acute kidney injury following a swarm of bees' sting at Iringa Regional Referral Hospital, Southern Highland-Tanzania: a case report.
J Med Case Rep
September 2024
Department of Obstetrics and Gynecology, Iringa Regional Referral Hospital, Iringa, Tanzania.
Article Synopsis
- Peritoneal dialysis is a safe and cost-effective treatment for children with acute kidney injury, especially in low-income countries, but is often limited to tertiary healthcare facilities, like in Tanzania.
- A case report highlights a 22-month-old boy who received urgent peritoneal dialysis after suffering kidney injury from a bee sting, albeit under risky conditions at a secondary health facility lacking proper resources.
- The conclusion emphasizes the need for collaboration to enhance the availability and safety of peritoneal dialysis in lower-level facilities, as access to higher-tier hospitals is often insufficient and delayed.
[Chronic urticaria as an atypical reaction after a vespid bite].
Rev Alerg Mex
June 2024
Unidad de Alergia, Hospital Universitario Fundación Alcorcón, Madrid, España.
Article Synopsis
- - A 56-year-old woman experienced severe itching and widespread hives after being stung by wasps, which required extensive treatment over 12 weeks with antihistamines and corticosteroids.
- - Allergy testing indicated that she had a normal tryptase level and was sensitized to venom from Polistes dominula, a type of wasp.
- - The patient began venom immunotherapy specific to Polistes dominula, which successfully prevented any further episodes of hives after treatment.
[Bullet ant-more than just a painful sting].
Dermatologie (Heidelb)
October 2024
Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum der Universität München, LMU München, Frauenlobstr. 9-11, 80337, München, Deutschland.
Unraveling wasp sensitization in a patient with systemic mastocytosis by CAP-inhibition assay.
Allergol Immunopathol (Madr)
September 2024
Allergy Department, Hospital Universitari Vall d´Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
Article Synopsis
- Systemic mastocytosis (SM) is a disorder that can cause severe allergic reactions, especially triggered by insect stings, and diagnosing indolent SM without skin symptoms is not uncommon.* -
- Venom immunotherapy (VIT) effectively reduces the risk of future reactions in patients with indolent SM, and it's crucial to personalize this treatment by distinguishing between true venom allergies and cross-reactivity.* -
- In a case study of a man who experienced anaphylaxis after wasp stings, molecular diagnosis did not clarify his allergies, so a CAP-inhibition assay was necessary, emphasizing the need for precise assessments in hymenoptera venom allergy.*
Bites and Stings: Exotic Causes of Stroke in Asia.
Cerebrovasc Dis Extra
October 2024
Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Article Synopsis
- There are some rare causes of strokes in Asia that aren't usually seen in Western countries, like snakebites, scorpion stings, and bee or wasp stings.
- These incidents can mostly happen to young men and have serious effects on their health and families, often leading to death or disabilities.
- More research is needed to understand how these stings and bites cause strokes and to find better ways to treat them.
[Research Progress in Detection of Bee Venom Allergens].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
August 2024
Department of Allergy, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
Article Synopsis
- Some people are allergic to stings from certain insects like bees, which can be very dangerous for them.
- In China, it's hard for doctors to figure out which insect is causing the allergy because the tools they have aren’t very accurate.
- Scientists are working on new ways to identify bee venom allergens, which will help doctors give better treatment to those who are allergic.
Venom immunotherapy in clinical practice: comparison of two ultra-rush protocols.
Eur Ann Allergy Clin Immunol
September 2024
Allergy and Clinical Immunology Department, São João Local Health Unit, Porto, Portugal.
Article Synopsis
- Ultra-rush venom immunotherapy is a quick way to help people avoid bad reactions to bee or wasp stings, and it has been shown to be safe and effective.
- In a study with 110 patients who were treated from 2008 to 2021, almost all completed the therapy, and many did not have any bad reactions.
- Younger people, beekeepers, and those treated for bee stings had more reactions, but starting with a low dose of 1 µg was found to be safe and could save time.