5 results match your criteria: "Hyderabad Rheumatology Centre[Affiliation]"

Myositis India: Early lessons from a patient support group in a resource-limited setting.

Int J Rheum Dis

September 2024

Division of Rheumatology and Clinical Immunology, Arthritis and Autoimmunity Center and UPMC Myositis Center, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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Article Synopsis
  • A 36-year-old woman was diagnosed with relapsing polychondritis after experiencing symptoms like scleritis and saddle nose deformity over a 17-year period.
  • Her condition showed only partial improvement despite various treatments, including corticosteroids and immunosuppressants.
  • Tocilizumab, a newer medication, was introduced in 2017, leading to significant stabilization of both her systemic and ocular symptoms for the last four years.
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Objective: Deficiency of adenosine deaminase 2 (DADA2) is a potentially fatal monogenic syndrome characterized by variable manifestations of systemic vasculitis, bone marrow failure, and immunodeficiency. Most cases are diagnosed by pediatric care providers, given the typical early age of disease onset. This study was undertaken to describe the clinical phenotypes and treatment response both in adults and in children with DADA2 in India.

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