6,149 results match your criteria: "Hydatidiform Mole"
Cureus
August 2024
Foundation School, Somerset NHS Foundation Trust, Somerset, GBR.
Quant Imaging Med Surg
September 2024
Department of Ultrasound Diagnosis, Gansu Provincial Maternity and Child-care Hospital, Lanzhou, China.
Background: Placental mesenchymal dysplasia (PMD) is a rare placental vascular malformation of unknown etiology. PMD may coexist with a healthy fetus, and its ultrasound appearance is similar to that of a hydatidiform mole, especially the partial type. Prenatal ultrasonography is vital for accurate diagnosis of these conditions.
View Article and Find Full Text PDFJ Clin Ultrasound
September 2024
Department of Obstetrics and Gynecology, Faculty of Medicine, Damascus University, Damascus, Syria.
This case report presents the association of a chorionic bump with a partial mole pregnancy in a 37-year-old G3P2 woman. The differential diagnosis of a partial mole was considered after transvaginal ultrasonography revealed a chorionic bump. Subsequent pathological analysis confirmed the diagnosis.
View Article and Find Full Text PDFHematol Oncol Clin North Am
December 2024
Department of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Pelvic Cancer, Karolinska University Hospital, 171 64 Stockholm, Sweden. Electronic address:
Hematol Oncol Clin North Am
December 2024
New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Gynecol Oncol
November 2024
Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Int J Mol Sci
August 2024
Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry 605006, India.
Gestational trophoblastic diseases (GTDs) encompass a spectrum of conditions characterized by abnormal trophoblastic cell growth, ranging from benign molar pregnancies to malignant trophoblastic neoplasms. This systematic review explores the molecular underpinnings of GTDs, focusing on genetic and epigenetic factors that influence disease progression and clinical outcomes. Based on 71 studies identified through systematic search and selection criteria, key findings include dysregulations in tumor suppressor genes such as , aberrant apoptotic pathways involving (B-cell lymphoma), and altered expression of growth factor receptors and microRNAs (micro-ribose nucleic acid).
View Article and Find Full Text PDFGynecol Minim Invasive Ther
July 2024
Department of Gynecological, Chengdu Focused Ultrasound Hospital, Chengdu, China.
Pan Afr Med J
August 2024
Department 'C' of Gynecology and Obstetrics, Tunis Maternity and Neonatology Center, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
BMC Cancer
August 2024
Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710004, China.
Background: Patients with choriocarcinoma (CC) accompanying chemoresistance conventionally present a poor prognosis. Whether ras protein activator like-1 (RASAL1) functions as a tumor promoter or suppressor depends on tumor types. However, the role of RASAL1 in process of chemoresistance of CC and underlying molecular mechanism remain elusive.
View Article and Find Full Text PDFJ Ultrasound
December 2024
Department of Radiodiagnosis, All India Institute of Medical Sciences (AIIMS), Raipur, 492001, Chhattisgarh, India.
Int J Reprod Biomed
May 2024
Department of Obstetrics and Gynecology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Background: Ectopic molar pregnancy (EMP) is a rare form of gestational trophoblastic disease that occurs when a hydatidiform mole implants outside the uterus.
Case Presentation: We describe a 35-yr-old woman with mild abdominal pain, delayed menstruation for 2 months, and high beta-human chorionic gonadotropin levels. Sonography revealed a heterogeneous hyperechoic mass in the left adnexa and fluid in the endometrial cavity, suggestive of a tubal EMP.
Am J Obstet Gynecol
July 2024
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The University of Arizona, Tucson, AZ.
Diseases
July 2024
The Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140, USA.
J Clin Pathol
July 2024
Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Aims: Specific identification of a hydatidiform mole (HM) and subclassification of a complete hydatidiform mole (CHM) or partial hydatidiform mole (PHM) are critical. This study aimed to reappraise the diagnostic performance of ultrasonography and histology with a refined diagnosis.
Methods: This was a retrospective, multicentre cohort study of 821 patients with histologically suspected HM specimens.
Clin Nucl Med
December 2024
Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Histopathology
December 2024
Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
Aims: Diagnostic separation of diandric triploid gestation, i.e. partial mole from digynic triploid gestation, is clinically relevant, as the former may progress to postmolar gestational trophoblastic neoplasia.
View Article and Find Full Text PDFReprod Sci
October 2024
Reproductive Medicine Center, The First Hospital of Lanzhou University, No. 1 Dong Gang Xi Road, Chengguan District, Lanzhou, 730000, Gansu, China.
To retrospectively analyze the fertility outcomes and prognosis of gestational trophoblastic disease (GTD) patients, providing a basis for targeted fertility guidance and counseling. 82 GTD patients of childbearing age who received treatment at the Obstetrics and Gynecology Department of Lanzhou University First Hospital from January 2016 to January 2023 were stratified into re-pregnancy (n = 20) and non-re-pregnancy (n = 33) cohorts based on their pregnancy outcomes. The impacts of various factors on pregnancy outcomes were subsequently evaluated, encompassing the rates of subsequent pregnancies, live births, miscarriages, ectopic pregnancies, and ongoing pregnancies.
View Article and Find Full Text PDFActa Med Philipp
June 2024
Division of Trophoblastic Diseases, Department of Obstetrics and Gynecology, Philippine General Hospital, University of the Philippines Manila.
Hydatidiform mole coexistent with a live fetus (CMCF) is a rare entity occurring in 1:20,000 to 1:100,000 pregnancies. Three mechanisms of this type are possible: (1) a singleton pregnancy consisting of partial mole with a triploid fetus, (2) a twin gestation consisting of an androgenic complete hydatidiform mole with a biparental diploid fetus, and (3) a twin gestation consisting of a biparental diploid fetus with a normal placenta and a partial hydatidiform mole (PHM) with a triploid fetus. The abnormal triploid fetus in a partial mole tends to die in the first trimester while the fetus coexisting with a complete or partial mole in the dizygotic twin pregnancy has a chance to survive.
View Article and Find Full Text PDFInt J Gynecol Pathol
January 2025
Center for the Precision Medicine of Trophoblastic Disease, Department of Pathology, Yale School of Medicine, New Haven, Connecticut.
Mixed gestational trophoblastic tumors are exceptionally rare and have variable clinicopathological presentations. We report 3 such tumors with different combinations of choriocarcinoma (CC), placental site trophoblastic tumor (PSTT), and epithelioid trophoblastic tumor (ETT). The patients' age ranged from 38 to 44 years.
View Article and Find Full Text PDFAsian J Surg
December 2024
Department of Pathology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, China.
BMJ Case Rep
June 2024
Obstetrics and Gynecology, Louisiana State University Health Sciences Center Shreveport, Shreveport, Louisiana, USA
J Int Med Res
June 2024
Department of Obstetrics and Gynecology, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, China.
We herein report a rare case of simultaneous intrauterine molar pregnancy and tubal pregnancy. A woman of childbearing age who had never been pregnant underwent an ultrasound examination 70 days after the onset of menopause. She had a history of ovulation induction.
View Article and Find Full Text PDFJ Med Case Rep
June 2024
Department of Gynecology and Andrology, Cliniques Universitaires Saint-Luc, 1200, Brussels, Belgique.
Background: This case describes the youngest patient documented in the literature who presented with a giant hydatidiform mole, effectively addressed through conservative treatment.
Case Presentation: Our department received a 20-year-old Caucasian patient who was admitted due to significant metrorrhagia in an undisclosed pregnancy. During examination, we identified a massive, highly vascularized hydatidiform mole measuring 22 cm (cm).