Assessment of compliance and therapeutic efficacy of albendazole treatment in Chinese patients with echinococcosis.

Background: Echinococcosis is an infectious parasitic disease that is extremely harmful to human health. Albendazole is provided free of charge to patients requiring medication under the central government finance transfer payment scheme for echinococcosis control and prevention in China. Our aim is to monitor the state of patient medication and its therapeutic impact, which will help improve medication compliance and the therapeutic effect.

Intermuscular hydatid cyst in the thigh musculature: a case report.

Introduction: Echinococcus granulosus, a tapeworm, is responsible for causing hydatid disease. Hydatid cysts rarely affect the musculoskeletal system, occurring in less than 5% of cases. This case report presents the clinical presentation, diagnosis, and management of muscle echinococcosis.

ECHINOCOCCUS MULTILOCULARIS IN NEW YORK WILDLIFE: DISTRIBUTION AND GENETIC DIVERSITY OF AN EMERGING PATHOGEN.

Echinococcus is a genus of cestode parasites of paramount veterinary and medical importance globally. Two species, Echinococcus granulosus sensu lato and Echinococcus multilocularis, are endemic to North America and are the etiologic agents of cystic echinococcosis and alveolar echinococcosis, respectively. North America is currently experiencing an epidemiological shift in the state of transmission, distribution, and prevalence of E.

Echinococcosis of the liver in Poland - review of the literature and our own clinical material.

Echinococcosis is considered one of the world's most dangerous zoonoses, and the tapeworm that causes it is one of the two most dangerous parasites to humans globally. Untreated cases may be associated with as high as 90% mortality. The incidence of this pathology is increasing.

Echinococcosis: An Uncommon Cause of Thoracic Pain.

Echinococcosis is caused by larvae, the metacestode stage of the tapeworm , and poses a public health issue in many developing countries. It generally affects a single organ, most commonly the liver or lungs, and rarely involves multiple organs. We present the case of a 24-year-old Indian man living in Portugal, who was admitted to the Emergency Department with left-sided thoracic pain radiating to the back.

Disseminated Abdominal Cystic Echinococcosis After Blunt Abdominal Trauma: A Case Report.

Rupture of a hydatid cyst can lead to the development of a disseminated form of intra-abdominal cystic echinococcosis if not diagnosed and treated promptly. Anaphylactic shock is a definite indication of cyst rupture. The presented clinical case was a young athlete with a disseminated form of cystic echinococcosis, which was investigated in 2023 at the Syzganov National Scientific Center for Surgery of Kazakhstan.

Rare presentation of Echinococcal Disease: A Systematic Review on Arterial Hydatid Cyst.

Background: Echinococcosis is a parasitic disease caused by Echinococcus granulosis that most commonly affects the liver (70%) and lungs (20%). Despite rarely reported, arterial echinococcosis represents a severe and potentially life-threatening condition but management strategies and related outcomes have not been fully investigated.

Methods: A comprehensive review of the international English literature was performed on PubMed, Scopus and Web of Science from inception to May 30, 2024 to identify relevant articles about arterial echinococcosis.

Development of a Copro-RPA-CRISPR/Cas12a assay to detect Echinococcus granulosus nucleic acids isolated from canine feces using NaOH-based DNA extraction method.

Background: Cystic echinococcosis (CE), caused by Echinococcus granulosus sensu lato (E. granulosus s.l.

The European Union One Health 2023 Zoonoses report.

This report by the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of zoonoses monitoring and surveillance activities carried out in 2023 in 27 Member States (MSs), the United Kingdom (Northern Ireland) and 10 non-MSs. Key statistics on zoonoses and zoonotic agents in humans, food, animals and feed are provided and interpreted historically. In 2023, the first and second most reported zoonoses in humans were campylobacteriosis and salmonellosis, respectively.

Narrowing the region of candidate genes that control the development of protoscoleces of Echinococcus multilocularis in the mouse liver.

Alveolar echinococcosis is a zoonosis caused by the larval stage of Echinococcus multilocularis. In previous studies, QTL analysis using C57BL/6 N (B6) and DBA/2 (D2) which differ in susceptibility suggested the presence of genes on chromosome 1 that control protoscolex development. In this study, we constructed several congenic mice with different chromosome 1 regions substituted to confirm the presence of responsible genes and to narrow down the regions where the responsible genes exist.

ELISA based seroprevalence and risk factors for three zoonotic parasites (Toxoplasma gondii, Echinococcus granulosus and Trichinella spiralis) in humans in Khyber Pakhtunkhwa, Pakistan.

Zoonotic parasitic infections can affect both animal and human health, while also having food safety and economic implications. These pathogens can also pose occupational risks for certain groups, including veterinary professionals, animal handlers, and butchers. This study was conducted in the district of Swabi located in the Khyber Pakhtunkhwa Province of northwestern Pakistan.

Risk factors associated with human echinococcosis: a systematic review and meta-analysis.

Introduction: Echinococcosis is a widespread zoonotic disease caused by tapeworms of the Echinococcus genus, manifesting in mature or larval forms. Cystic echinococcosis (CE) and alveolar echinococcosis (AE) are the primary types affecting humans, linked, respectively, to and . This study is a systematic review and meta-analysis of the risk factors associated with CE and AE in humans.

A liver CT based nomogram to preoperatively predict lung metastasis secondary to hepatic alveolar echinococcosis.

Purpose: To develop a nomogram based on liver CT and clinical features to preoperatively predict lung metastasis (LM) secondary to hepatic alveolar echinococcosis (HAE).

Methods: A total of 291 consecutive HAE patients from Institution A undergoing preoperative abdominal contrast-enhanced CT and chest unenhanced CT were retrospectively reviewed, and were randomly divided into the training and internal validation sets at the 7:3 ratio. 82 consecutive patients from Institution B were enrolled as an external validation set.

Splenic Lymphoma Mimicking a Hydatid Cyst Causing a Diagnostic Challenge: A Case Report.

Splenic lymphoma, particularly primary splenic diffuse large B-cell lymphoma (PS-DLBCL), is a rare malignancy that often presents with nonspecific symptoms, complicating diagnosis. This case report describes a 44-year-old female with left flank pain and nausea whose imaging studies, including ultrasound and CT, revealed a well-defined heterogeneous lesion in the spleen and left pleural effusion, initially suggesting a hydatid cyst. Despite negative serological tests for echinococcosis, clinical suspicion remained due to the endemic presence of the disease.

A rare case of recurrent spinal hydatid cyst in a 17-year-old man with neurological deficits and balance impairment.

Background: Hydatid cysts are caused by the larval stage of the tapeworm parasite Echinococcus granulosus, leading to a rare but significant zoonotic infection. This disease is primarily observed in regions with prevalent agricultural and livestock practices. While the liver, lungs, and brain are most affected, spinal involvement is notably rare.

[Hepatic T cell subtypes and functional analysis among alveolar echinococcosis patients using single-cell RNA sequencing].

Objective: To investigate T cell subtypes and their functions in liver immune microenvironments among patients with alveolar echinococcosis (AE) using single-cell RNA sequencing (scRNA-seq).

Methods: Four AE patients that were admitted to Qinghai Provincial People's Hospital in 2023 for hepatic surgery for the first time were enrolled, and liver specimens were sampled 1 cm (peri-lesion, PL group) and > 5 cm from AE lesions (distal lesion, DL group) among each patient. Finally, a total of eight liver specimens were sampled from four AE patients for scRNA-seq analysis.

[Spatiotemporal distribution of newly diagnosed echinococcosis patients in Qinghai Province from 2016 to 2022].

Objective: To investigate the spatiotemporal distribution characteristics and potential influencing factors of newly diagnosed echinococcosis cases in Qinghai Province from 2016 to 2022, so as to provide insights into the formulation of the echinococcosis control strategy in Qinghai Province.

Methods: The number of individuals screened for echinococcosis, number of newly diagnosed echinococcosis cases, number of registered dogs and number of stray dogs were captured from the annual reports of echinococcosis control program in Qinghai Province from 2016 to 2022, and the detection of newly diagnosed echinococcosis cases was calculated. The number of populations, precipitation, temperature, wind speed, sunshine hours, average altitude, number of year-end cattle stock, number of year-end sheep stock, gross domestic product (GDP) per capita, and number of village health centers in each county (district) of Qinghai Province were captured from the , and county-level electronic maps in Qinghai Province were downloaded from the National Platform for Common Geospatial Information Services.

Dissimilar local risk factors among patients diagnosed with cystic echinococcosis upon voluntary screening in highly endemic regions of Kyrgyz Republic.

Echinococcosis is a parasitic invasion caused by a cestode of the genus . Kyrgyzstan is a country in Central Asia known for an extremely high incidence of echinococcosis. A total of 10 093 subjects were screened in the Osh, Naryn and Batken regions of Kyrgyzstan in 2015–2017 by ultrasound and questioned for potential risk factors.

Expression and serodiagnostic efficacy of a novel echinococcosis-specific recombinant fusion antigen rAgB8/1-Em18-Eg95.

Echinococcosis lacks sensitive serological diagnostic tools. The echinococcosis-specific antigens Eg95, AgB8/1 and the Em18 gene sequences were fused and expressed as the novel recombinant antigens rAgB8/1-Em18-Eg95 (T3) and rEm18-Eg95 (T2), used for the diagnosis of hydatid disease, prepared into an enzyme-linked immunosorbent reaction (ELISA) kit, and evaluated for their serological diagnostic value. The relative molecular weight of the T3 protein was 88.

Low-cost acrylic cranioplasty using an implant cast on a pre-printed 3D polylactic acid model in a child with a complicated osteolytic extradural hydatid cyst.

Cranioplasty to restore calvarial defects involves reconstruction with alloplastic materials or autologous tissues in order to provide the best protection to all intracranial contents. Sometimes, autologous bone may not be available; therefore, different materials have emerged such as polymethylmethacrylate plate, titanium mesh, and hydroxyapatite. However, when it is impossible to replace the autologous bone, the aesthetic result is generally unsatisfactory.

Cerebral Hydatidosis in a Lamb.

A 6-month-old Afshari male lamb was examined on a semi-intensive farm due to anorexia and neurologic signs, including head tilt, circling, bilateral positive menace response and stupor. The sheep was slaughtered and necropsied. After routine parasitology and histopathology procedures, the occurrence of cerebral hydatidosis was confirmed.