2 results match your criteria: "Huzhou Center Blood Station[Affiliation]"
Prevalence and molecular characteristics of occult hepatitis B virus infection among blood donors in Huzhou City, eastern China.
Gene
November 2024
Departmentof Precision Medicine, Huzhou Central Hospital, Affiliated Central Hospital, Huzhou University, Huzhou, Zhejiang 313000, China; Huzhou Key Laboratory of Precision Medicine Research and Translation for Infectious Diseases, Huzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, Zhejiang 313000, China. Electronic address:
Article Synopsis
- Occult hepatitis B virus (HBV) infection (OBI) poses a challenge for HBV control; a study in Huzhou City found a 0.070% prevalence of OBI among blood donors.
- Among OBI cases, genotype C was the most common, and specific mutations in the surface (S) gene were associated with the infection, including several novel mutations not previously documented.
- The study highlights the need for further research on these S gene mutations to understand their role in OBI and improve HBV transmission prevention in blood transfusions.
Efficacy and Safety of Hepatic Arterial Infusion Therapy with Cinobufacini in Advanced Hepatocellular Carcinoma with Macrovascular Invasion: A Retrospective Cohort Study.
Cancer Manag Res
March 2024
Laboratory of Blood Transfusion Research, Huzhou Center Blood Station, Huzhou, People's Republic of China.
Background: The presence of macrovascular invasion (MVI) is associated with poor prognosis in advanced hepatocellular carcinoma (HCC). This study aims to evaluate the efficacy and safety of Cinobufacini therapy via hepatic arterial infusion (HAI) in advanced HCC patients with MVI.
Methods: The clinical records of 130 consecutive patients with unresectable advanced HCC and MVI who had received Cinobufacini or cisplatin plus 5-fluorouracil (CF) treatment via HAI were retrospectively analyzed.