161 results match your criteria: "Huntsman Mental Health Institute[Affiliation]"
Sci Adv
March 2024
Department of Psychiatry, Huntsman Mental Health Institute, University of Utah, Salt Lake City, UT 84108, USA.
Heliyon
March 2024
Department of Occupational and Environmental Medicine, Inha University School of Medicine, Incheon, Republic of Korea.
Background: Particulate air pollution and residential greenness are associated with sleep quality in the general population; however, their influence on maternal sleep quality during pregnancy has not been assessed.
Objective: This cross-sectional study investigated the individual and interactive effects of exposure to particulate matter (PM) air pollution and residential greenness on sleep quality in pregnant women.
Methods: Pregnant women (n = 4933) enrolled in the Korean Children's Environmental Health Study with sleep quality information and residential address were included.
J Occup Environ Med
May 2024
From the Center for Mental Healthcare and Outcomes Research, Central Arkansas Veterans Healthcare System, Little Rock, Arkansas (B.J.G., M.C.W., J.P.); Psychiatric Research Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas (B.J.G., M.C.W., J.P.); Lyda Hill Institute for Human Resilience, University of Colorado-Colorado Springs, Colorado Springs, Colorado (B.J.G., C.C.B., M.M., A.J.S.); School of Business, La Salle University, Philadelphia, Pennsylvania (P.T.C.); South Central Mental Illness Research, Education, and Clinical Center, Little Rock, Arkansas (M.C.W., J.P.); Department of Psychiatry and Behavioral Sciences, University of California-San Francisco, San Francisco, California (S.M.); San Francisco Veterans Health Care System, San Francisco, California (S.M.); Department of Psychiatry, Geisel School of Medicine at Dartmouth and Dartmouth Health, Hanover, New Hampshire (M.S.D., R.E.B.); Huntsman Mental Health Institute, University of Utah, Salt Lake City, Utah (H.W., T.L., A.J.S.); and Department of Psychiatry and Behavioral Health, The Ohio State University, Columbus, Ohio (S.A.L.).
Bipolar Disord
March 2024
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia.
Mol Psychiatry
April 2024
Department of Psychiatry & Behavioral Health, Stony Brook University, Stony Brook, NY, USA.
This review describes the Hierarchical Taxonomy of Psychopathology (HiTOP) model of psychosis-related psychopathology, the psychosis superspectrum. The HiTOP psychosis superspectrum was developed to address shortcomings of traditional diagnoses for psychotic disorders and related conditions including low reliability, arbitrary boundaries between psychopathology and normality, high symptom co-occurrence, and heterogeneity within diagnostic categories. The psychosis superspectrum is a transdiagnostic dimensional model comprising two spectra-psychoticism and detachment-which are in turn broken down into fourteen narrow components, and two auxiliary domains-cognition and functional impairment.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2023
Department of Community Health Systems, University of California, San Francisco, San Francisco, CA, United States.
The aim of this narrative review is to consolidate knowledge on the role of the hypothalamic-pituitary-adrenal (HPA) axis in depression pathophysiology at different reproductive stages across the female lifespan. Despite growing evidence about the impact of gonadal hormones on mood disorders, no previous review has examined the interaction between such hormonal changes and the HPA axis within the context of depressive disorders in women. We will focus on HPA axis function in depressive disorders at different reproductive stages including the menstrual cycle (e.
View Article and Find Full Text PDFFront Psychiatry
December 2023
Huntsman Mental Health Institute, Salt Lake City, UT, United States.
Introduction: The externalizing disorders of attention deficit hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and conduct disorder (CD) are common in adolescence and are strong predictors of adult psychopathology. While treatable, substantial diagnostic overlap complicates intervention planning. Understanding which factors predict the onset of each disorder and disambiguating their different predictors is of substantial translational interest.
View Article and Find Full Text PDFMol Genet Metab
January 2024
Department of Psychiatry, University of Utah Huntsman Mental Health Institute, Salt Lake City, UT, USA.
Background: Pegvaliase, an enzyme substitution therapy, is a treatment option for phenylketonuria (PKU). Due to the neuropathophysiology and disease burden of PKU, individuals can experience baseline anxiety unrelated to pegvaliase therapy. In addition, there are aspects of pegvaliase therapy that may be anxiety-inducing for those considering or receiving treatment.
View Article and Find Full Text PDFPediatr Pulmonol
March 2024
Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
Background: Rates of venous thromboembolism (VTE) are increasing in people with cystic fibrosis (PwCF). Providers treating VTE in PwCF have reported low confidence concerning anticoagulant drug selection, dose, duration, and drug-drug interactions. As there are currently no published reports regarding management of VTE in PwCF, our objective was to describe the management of VTE in PwCF.
View Article and Find Full Text PDFBipolar Disord
December 2023
Department of Psychiatry, University of Toronto, Toronto, Canada.
medRxiv
October 2023
Huntsman Mental Health Institute, Salt Lake City, UT 84103.
Background: Thought disorder (TD) is a sensitive and specific marker of risk for schizophrenia onset. Specifying factors that predict TD onset in adolescence is important to early identification of youth at risk. However, there is a paucity of studies prospectively predicting TD onset in unstratified youth populations.
View Article and Find Full Text PDFFront Psychiatry
October 2023
Cognitive Neuroscience Center, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, United States.
Introduction: Emerging literature suggests that childhood trauma may influence facial emotion perception (FEP), with the potential to negatively bias both emotion perception and reactions to emotion-related inputs. Negative emotion perception biases are associated with a range of psychiatric and behavioral problems, potentially due or as a result of difficult social interactions. Unfortunately, there is a poor understanding of whether observed negative biases are related to childhood trauma history, depression history, or processes common to (and potentially causative of) both experiences.
View Article and Find Full Text PDFJ Med Case Rep
October 2023
Department of Biomedical Engineering, University of Utah, Salt Lake City, USA.
Background: Severe forms of depression have been linked to hyperactivity of the subcallosal cingulate cortex. The ability to stimulate the subcallosal cingulate cortex or associated circuits noninvasively and directly would maximize the number of patients who could receive treatment. To this end, we have developed an ultrasound-based device for effective noninvasive modulation of deep brain circuits.
View Article and Find Full Text PDFbioRxiv
October 2023
Department of Psychiatry, Huntsman Mental Health Institute, School of Medicine, University of Utah, Salt Lake City, USA.
JAMA Pediatr
December 2023
Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics, Harvard Law School, Cambridge, Massachusetts.
Camb Q Healthc Ethics
October 2023
Huntsman Mental Health Institute, Department of Psychiatry, University of Utah, Salt Lake City, UT, USA.
Critics of medical aid in dying (MAID) often argue that it is impermissible because background social conditions are insufficiently good for some persons who would utilize it. I provide a critical evaluation of this view. I suggest that receiving MAID is a sort of "hard choice," in that death is bad for the individual and only promotes that person's interests in special circumstances.
View Article and Find Full Text PDFTransl Psychiatry
October 2023
Department of Applied Mathematics, University of Washington, Seattle, WA, USA.
Three-quarters of lifetime mental illness occurs by the age of 24, but relatively little is known about how to robustly identify youth at risk to target intervention efforts known to improve outcomes. Barriers to knowledge have included obtaining robust predictions while simultaneously analyzing large numbers of different types of candidate predictors. In a new, large, transdiagnostic youth sample and multidomain high-dimension data, we used 160 candidate predictors encompassing neural, prenatal, developmental, physiologic, sociocultural, environmental, emotional and cognitive features and leveraged three different machine learning algorithms optimized with a novel artificial intelligence meta-learning technique to predict individual cases of anxiety, depression, attention deficit, disruptive behaviors and post-traumatic stress.
View Article and Find Full Text PDFNutrients
September 2023
Diagnosis and Treatment of Congenital Metabolic Diseases Unit (UDyTEMC), Department of Pediatrics, Faculty of Medicine, Clinical University Hospital of Santiago de Compostela, University of Santiago de Compostela, CIBERER, MetabERN, Institute of Clinical Research of Santiago de Compostela (IDIS), Rúa de San Francisco s/n, 15706 Santiago de Compostela, Spain.
Many adults with phenylketonuria (PKU) rely on medical nutrition therapy (MNT; low phenylalanine (Phe) diet with protein substitutes/medical foods) to maintain blood Phe concentrations within recommended ranges and prevent PKU-associated comorbidities. Despite disease detection through newborn screening and introduction of MNT as early as birth, adherence to MNT often deteriorates from childhood onwards, complicating the assessment of its effectiveness in the long term. Via a modified Delphi process, consensus (≥70% agreement) was sought on 19 statements among an international, multidisciplinary 13-member expert panel.
View Article and Find Full Text PDFPalliative interventions are intended to alleviate suffering and improve quality, not quantity, of life and are not intended to cure illness. In psychiatry, uncertainty about which interventions count as palliative stems from the fact that psychiatry generally prioritizes symptom management irrespective of diagnosis or specific pathophysiology of illness. This commentary on a case considers how distinctions between palliative and other psychiatric interventions might not be all that helpful in resolving clinical and ethical questions about which interventions are-and when they are-appropriate.
View Article and Find Full Text PDFJ Alzheimers Dis
October 2023
Department of Neurology, University of Utah, Salt Lake City, UT, USA.
Background: Despite reports of gross motor problems in mild cognitive impairment (MCI) and Alzheimer's disease (AD), fine motor function has been relatively understudied.
Objective: We examined if finger tapping is affected in AD, related to AD biomarkers, and able to classify MCI or AD.
Methods: Forty-seven cognitively normal, 27 amnestic MCI, and 26 AD subjects completed unimanual and bimanual computerized tapping tests.