103,339 results match your criteria: "Hungary; VIB Structural Biology Research Center[Affiliation]"

Background: Breastfeeding in Syria is a common practice supported by social norms, family traditions, and cultural values. In Hungary, recent statistics show that exclusive breastfeeding is significantly lower than the recommendation of the World Health Organization. Understanding the perspectives of educated young ladies is crucial for discovering the difficulties of breastfeeding practices within Syrian-Hungarian societies.

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Background: disordered eating (DE) and eating disorders (ED) can negatively impact athletes' health, wellbeing, and athletic performance.

Objective: this cross-sectional study aims to assess DE risk, body composition, and nutrition knowledge among elite Hungarian athletes.

Methods: DE risk was assessed using DESA-6H and EAT-26 scales, nutrition knowledge through the Abridged Nutrition for Sport Knowledge Questionnaire (A-NSKQ), and body composition with the OMRON BF511 device.

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Article Synopsis
  • The study evaluates the ability of three AI chatbots (Gemini, Microsoft Copilot, and ChatGPT 4.0) to create personalized weight-loss diet plans for different genders and caloric levels (1400-1800 kcal).
  • All chatbots produced satisfactory diet quality scores (DQI-I > 70), but struggled with achieving optimal balance in macronutrient distributions.
  • ChatGPT 4.0 excelled in caloric accuracy, while Gemini had notable inconsistencies, suggesting that while AI shows promise in personalized nutrition, it still needs improvement and should complement, not replace, human dietetic expertise.
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Background/objectives: Both hyperandrogenism (HA) and vitamin D deficiency (VDD) can separately lead to impaired vascular reactivity and ovulatory dysfunction in fertile females. The aim was to examine the early interactions of these states in a rat model of PCOS.

Methods: Four-week-old adolescent female rats were divided into four groups: vitamin D (VD)-supplemented ( = 12); VD-supplemented and testosterone-treated ( = 12); VDD- ( = 11) and VDD-and-testosterone-treated ( = 11).

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This study attempted to isolate and identify pedospheric microbes originating in dumpsites and utilized them for the degradation of selected synthetic polymers for the first time in a cost-effective, ecologically favorable and sustainable manner. Specifically, low-density polyethylene (LDPE) and polyurethane (PUR) were converted by the isolated fungi, i.e.

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Article Synopsis
  • Neuroinflammation contributes to the worsening of neurodegenerative diseases, driven by immune system activation and release of inflammatory molecules.
  • Medicinal plants show promise as natural alternatives to reduce neuroinflammation, with specific plants identified for their ability to lower pro-inflammatory cytokines and enhance antioxidant defenses.
  • Future research should aim for standardized dosages and safety assessments, utilizing advanced methods to improve the clinical use of these plants in treating neurodegenerative conditions.
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Cytotoxic Activity of Bisphosphonic Derivatives Obtained by the Michaelis-Arbuzov or the Pudovik Reaction.

Pharmaceuticals (Basel)

January 2025

Department of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3, 1111 Budapest, Hungary.

Methylenebisphosphonic derivatives including hydroxy-methylenebisphosphonic species may be of potential biological activity, and a part of them is used in the treatment of bone diseases. Methylenebisphosphonates may be obtained by the Michaelis-Arbuzov reaction of suitably α-substituted methylphosphonates and trialkyl phosphites or phosphinous esters, while the hydroxy-methylene variations are prepared by the Pudovik reaction of α-oxophosphonates and different >P(O)H reagents, such as diethyl phosphite and diarylphosphine oxides. After converting α-hydroxy-benzylphosphonates and -phosphine oxides to the α-halogeno- and α-sulfonyloxy derivatives, they were utilized in the Michaelis-Arbuzov reaction with trialkyl phosphites and ethyl diphenylphosphinite to afford the corresponding bisphosphonate, bis(phosphine oxide) and phosphonate-phosphine oxide derivatives.

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: Peripheral artery disease (PAD) is a prevalent vascular condition characterized by arterial narrowing, which impairs blood flow and manifests as intermittent claudication, a pain or cramping sensation induced by physical activity or ambulation. Walking distance is a crucial clinical indicator of peripheral artery disease, and it correlates with the disease severity and risk of mortality. It reflects the severity of the disease, with reduced mobility indicating an increased risk of morbidity.

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Barbell squats are commonly used in strength training, but the anterior-posterior displacement of the Center of Mass (COM) may impair joint stability and increase injury risk. This study investigates the key factors influencing COM displacement during different squat modes.; Methods: This study recruited 15 male strength training enthusiasts, who performed 60% of their one-repetition maximum (1RM) in the Front Barbell Squat (FBS), High Bar Back Squat (HBBS), and Low Bar Back Squat (LBBS).

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Investigation of Sliding Mode Control in the Nonlinear Modeling of Cordless Jigsaws.

Sensors (Basel)

January 2025

Department of Electrical Engineering and Mechatronics, Faculty of Engineering, Vehicles and Mechatronics Institute, University of Debrecen, Ótemető Str. 2-4., H-4028 Debrecen, Hungary.

The aim of this paper was to reduce the current spikes in battery-powered saw motors by designing and implementing a sliding mode model-following adaptive controller. The proposed controller reduces overcurrent consumption, improves system energy efficiency, and effectively maximizes battery runtime, especially under high-load conditions. By applying nonlinear compensation techniques, the controller can ensure smooth motor operation, reduce mechanical stress, and prolong tool life.

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Developing a Health Support System to Promote Care for the Elderly.

Sensors (Basel)

January 2025

Physiological Controls Research Center, University Research and Innovation Center, Obuda University, 1034 Budapest, Hungary.

In light of the demographic shift towards an aging population, there is an increasing prevalence of dementia among the elderly. The negative impact on mental health is preventing individuals from taking proper care of themselves. For individuals requiring hospital care, those receiving home care, or as a precaution for a specific individual, it is advantageous to utilize monitoring equipment to track their biological parameters on an ongoing basis.

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The processing of beans begins with a particularly time-consuming procedure, the hydration of the seeds. Ultrasonic treatment (US) represents a potential environmentally friendly method for process acceleration, while near-infrared spectroscopy (NIR) is a proposedly suitable non-invasive monitoring tool to assess compositional changes. Our aim was to examine the hydration process of red kidney beans of varying sizes and origins.

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Altered Pattern of Serum N-Glycome in Subarachnoid Hemorrhage and Cerebral Vasospasm.

J Clin Med

January 2025

Institute of Chemistry, Faculty of Materials Science and Engineering, University of Miskolc, 3515 Miskolc, Hungary.

: Subarachnoid hemorrhage is a serious condition caused by ruptured intracranial aneurysms, resulting in severe disability mainly in young adults. Cerebral vasospasm is one of the most common complication of subarachnoid hemorrhage; thus, active prevention is key to improve the prognosis. The glycosylation of proteins is a critical quality attribute which is reportedly altered in patients diagnosed with acute ischemic stroke.

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Inflammatory bowel diseases (IBDs), encompassing Ulcerative Colitis (UC) and Crohn's Disease (CD), are chronic inflammatory disorders affecting the gastrointestinal tract. The association between IBD and colorectal cancer (CRC) is well-documented. Multiple factors have been identified as contributors to the risk of developing CRC in patients with IBD, including duration of disease, disease extension, family history of CRC, co-existance of primary sclerosing cholangitis (PSC), and potentially the presence of post-inflammatory polyps (PIPs).

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Limited research has explored histamine intolerance from the perspective of primary caregivers. Our objective was to develop a practical symptom profile from the standpoint of general practice. We also aimed to gather data on the frequency and timing of disease progression and to establish a staging system.

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: The aim of this study was to compare the outcomes of stiff wire-based 2D3D, 3D3D image fusion (IF), and non-image fusion techniques for simple zone 2 and zone 3 TEVAR cases in terms of radiation exposure, contrast dose, and fusion and projection accuracy. : A single-center retrospective observational study was conducted based on data gathered from patients who underwent TEVAR between 2016 and 2023 at our tertiary aortic referral center. Those who underwent Z2 and Z3 TEVAR during the indicated period were included.

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The Synthesis, Crystal Structure, Modification, and Cytotoxic Activity of α-Hydroxy-Alkylphosphonates.

Molecules

January 2025

Department of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3., 1111 Budapest, Hungary.

A series of α-hydroxy-alkylphosphonates and α-hydroxy-alkylphosphine oxides were synthesized by the Pudovik reaction of acetaldehyde and acetone with dialkyl phosphites or diarylphosphine oxides. The additions were performed in three different ways: in liquid phase using triethylamine as the catalyst (1), on the surface of AlO/KF solid catalyst (2), or by a MW-assisted NaCO-catalyzed procedure (3). In most of the cases, our methods were more efficient and more robust than those applied in the literature.

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Synthesis of Alkyl α-Amino-benzylphosphinates by the Aza-Pudovik Reaction; The Preparation of the Butyl Phenyl--phosphinate Starting P-Reagent.

Molecules

January 2025

Department of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3, 1111 Budapest, Hungary.

Butyl phenyl--phosphinate that is not available commercially was prepared from phenyl--phosphinic acid by three methods: by alkylating esterification (i), by microwave-assisted direct esterification (ii), and unexpectedly, by thermal esterification (iii). Considering the green aspects, selectivity and scalability, the thermal variation seemed to be optimal. However, there was need for prolonged heating.

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Resveratrol-Based Carbamates as Selective Butyrylcholinesterase Inhibitors: Design, Synthesis, Computational Study and Biometal Complexation Capability.

Molecules

January 2025

Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Trg Marka Marulića 19, HR-10 000 Zagreb, Croatia.

Considering our previous experience in the design of new cholinesterase inhibitors, especially resveratrol analogs, in this research, the basic stilbene skeleton was used as a structural unit for new carbamates designed as potentially highly selective butyrylcholinesterase (BChE) inhibitors with excellent absorption, distribution, metabolism, excretion and toxicity ADMET properties. The inhibitory activity of newly prepared carbamates - was tested toward the enzymes acetylcholinesterase (AChE) and BChE. In the tested group of compounds, the leading inhibitors were and , which achieved excellent selective inhibitory activity for BChE with IC values of 0.

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g-CN Modified with Metal Sulfides for Visible-Light-Driven Photocatalytic Degradation of Organic Pollutants.

Molecules

January 2025

Research Group of Environmental and Inorganic Photochemistry, Center for Natural Sciences, Faculty of Engineering, University of Pannonia, P.O. Box 158, H-8201 Veszprém, Hungary.

Graphitic carbon nitride (g-CN) proved to be a promising semiconductor for the photocatalytic degradation of various organic pollutants. However, its efficacy is limited by a fast electron hole recombination, a restricted quantity of active sites, and a modest absorption in the visible range. To overcome these limitations, g-CN-BiS and g-CN-ZnS composites were effectively produced utilizing a starch-assisted technique.

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Carbon Nanosphere-Based TiO Double Inverse Opals.

Molecules

January 2025

Institute of Physical Metallurgy, Metal Forming and Nanotechnology, University of Miskolc, H-3515 Miskolc, Hungary.

Inverse opals (IOs) are intensively researched in the field of photocatalysis, since their optical properties can be fine-tuned by the initial nanosphere size and material. Another possible route for photonic crystal programming is to stack IOs with different pore sizes. Accordingly, single and double IOs were synthesized using vertical deposition and atomic layer deposition.

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Medik. (CBP) is a species with antibacterial, anti-inflammatory, antioxidant, anticancer, and hepatoprotective effects. We have chosen to study this species because, although it is a common plant with a distinctive fruit appearance, its effects are not fully understood.

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According to World Health Organization (WHO) data, 16% of people are affected by infertility across the globe. One underlying factor is the age-related decline of ovarian reserve (DOR), which can lead to a higher chance of infertility and has no widely accepted treatment currently. Specific supplements and moderate exercise have been shown to improve fertility; however, there is no consensus to date on the type of exercise providing the best results.

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Simplified Model for the Behaviour of Asphalt Mixtures Depending on the Time and the Frequency Domain.

Materials (Basel)

January 2025

Department of Highway and Railway Engineering, Budapest University of Technology and Economics, Műegyetem Rakpart 3, H-1111 Budapest, Hungary.

Sigmoid functions are widely used for the description of viscoelastic material properties of asphalt mixtures. Unfortunately, there are still no known closed functions for describing connections among model parameters in the time and the frequency domains. In most cases, complicated interconversion methods are applied for the conversion of viscoelastic material properties.

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Optimization of In-Situ Growth of Superconducting Al/InAs Hybrid Systems on GaAs for the Development of Quantum Electronic Circuits.

Materials (Basel)

January 2025

CNR-IOM-Istituto Officina dei Materiali, Consiglio Nazionale delle Ricerche, 34149 Trieste, Italy.

Hybrid systems consisting of highly transparent channels of low-dimensional semiconductors between superconducting elements allow the formation of quantum electronic circuits. Therefore, they are among the novel material platforms that could pave the way for scalable quantum computation. To this aim, InAs two-dimensional electron gases are among the ideal semiconductor systems due to their vanishing Schottky barrier; however, their exploitation is limited by the unavailability of commercial lattice-matched substrates.

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