1 results match your criteria: "Hunan University of Medicine No. 492 Jinxi South Road[Affiliation]"
Bmi-1 plays an important role in preventing bone aging by regulating the bone microenvironment.
Int J Clin Exp Pathol
December 2024
School of Stomatology, Hunan University of Medicine No. 492 Jinxi South Road, Huaihua 418000, Hunan, China.
Background: B-cell specific Moloney MLV insertion site-1 (Bmi-1) belongs to the polycomb group (PcG) gene and is a transcriptional suppressor to maintain appropriate gene expression patterns during development. To investigate whether the Bmi-1 gene has a corrective effect on bone senescence induced in Bmi-1 mice through regulating the bone microenvironment.
Methods: Littermate heterozygous male and female mice (Bmi-1) were used in this study.