2 results match your criteria: "Hunan Clinic Center of Pediatric Nephrology[Affiliation]"
[Effect of catechin microcapsule on the repair of DNA damage in glomerular mesangial cells induced by H2O2].
Zhong Nan Da Xue Xue Bao Yi Xue Ban
February 2007
Laboratory of Pediatric Nephrology, Institute of Pediatrics, Second Xiangya Hospital, Central South University, Hunan Clinic Center of Pediatric Nephrology, Changsha 410011, China.
Objective: To explore the effect and possible mechanism of catechin microcapsulation on the repair of DNA damage in glumreular mesangial cells (GMCs) induced by H2O2.
Methods: According to H2O2 concentration, the experiment GMCs were divided into 6 groups: a control group, 50 micromol/L group, 100 micromol/L group, 150 micromol/L group, 200 micromol/L group and 250 micromol/L group. Each group was sub-divided into 3 groups: 6 h group, 12 h group and 24 h group, in order to determining the optimum dose and the best time of detecting the DNA damage in GMCs.
[Ability of catechin to eliminate O2-* and *OH].
Zhong Nan Da Xue Xue Bao Yi Xue Ban
February 2006
Laboratory of Pediatric Nephrology, Institute of Pediatrics, Second Xiangya Hospital, Central South University, Hunan Clinic Center of Pediatric Nephrology, Changsha.
Objective: To investigate the eliminating ability of catechin to eliminate O2-* and *OH.
Methods: The ability of catechin to clear away O2-* and *OH was respectively measured by faintness chemiluminescence and spin trapping assay.
Results: IC50 that catechin eliminated O2-* and *OH was 6.