11 results match your criteria: "Hunan Children Hospital[Affiliation]"
Pak J Pharm Sci
March 2024
Department of Anesthesiology, Hunan Children' Hospital, Changsha City, Hunan, China.
Evidence suggests that surgical procedures can effect the central nervous system and lead to changes in mood and behavior, rarely understood about the role of acute inflammation in promoting acute anxiety postoperatively. This study was designed to explore the possible mechanism of dexmedetomidine (DEX, a2-adrenergic receptor agonist) for reducing acute postoperative anxiety, which may be related to the activation of nuclear factor kappa B (NF-κB) and downstream signal pathway in the hippocampus. Experiments were conducted with rat, the elevated plus-maze and open field test were performed to evaluate anxiety-like behavior.
View Article and Find Full Text PDFEpilepsy Res
February 2024
Department of Pharmacy, Hunan Children Hospital, Changsha, Hunan 410007, China. Electronic address:
Background: Dietary nutrient supplements are helpful in the treatment of many diseases, but their effect on epilepsy is still controversial. This study aimed to evaluate the association between dietary intake of multiple nutrients and epilepsy.
Methods: A total of 3963 participants from the NHANES database were involved in this study.
J Transl Med
June 2022
Department of Otolaryngology Head and Neck Surgery, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Background: Nasopharyngeal carcinoma (NPC) is a malignant tumor of epithelial origin in head and neck with high incidence rate in Southern China. C2orf40 has been identified as a tumor suppressor gene in many cancers. However, the roles of C2orf40 in nasopharyngeal carcinoma has not been studied.
View Article and Find Full Text PDFPaediatr Anaesth
July 2021
Department of Anesthesiology, Hunan Children' Hospital, Changsha, China.
Background: Surgery results in systemic inflammation, which can affect the central nervous system, leading to changes in mood, emotion, and behavior. Our previous study has shown that compared to midazolam, dexmedetomidine premedication effectively decreased children's postoperative anxiety.
Aim: To investigate whether dexmedetomidine infusion before hernia repair alleviates postoperative systemic inflammation in children and whether postoperative anxiety may be associated with postoperative inflammation.
Biomed Res Int
December 2019
Aier School of Ophthalmology, Central South University, Aier Eye Institute, Changsha, Hunan, China.
Object: Retinal ischemia-reperfusion (I/R) injury is a common pathological process in many ophthalmic diseases; there are no effective therapeutic approaches available currently. Increasing evidence indicates that microglia mediated neuroinflammation plays an important role in the retinal I/R injury. In this study, we aimed to investigate the roles of chemokine receptor CXCR5 in the pathological process of retinal I/R injury model.
View Article and Find Full Text PDFPaediatr Anaesth
August 2019
Department of Anesthesiology, Xiangya Hospital of Central South University, Changsha, China.
Background: Perioperative anxiety is common in pediatric patients undergoing surgery.
Aims: The aim of this study was to determine whether an infusion of dexmedetomidine prior to hernia repair in children provides better postoperative anxiety outcomes that a preoperative infusion of midazolam.
Methods: Ninety 6-11-year-old children, who were scheduled to undergo elective hernia repair, were enrolled for this double-blind, randomized controlled trial.
Pediatr Transplant
September 2019
Department of Urological Organ Transplantation, The Second Xiangya Hospital of Central South University, Changsha, China.
Gene
June 2017
Institute of Dermatology and Department of Dermatology of First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, China; Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, China, Hefei, Anhui, China; State key Laboratory Incubation Base of Dermatology, Anhui Medical University, Hefei, Anhui, China. Electronic address:
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease. The 5q22.1 region was found to have an association with AD in our previous genome-wide association study (GWAS).
View Article and Find Full Text PDFSeizure
September 2014
Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China. Electronic address:
Purpose: To investigate the prevalence and clinical characteristics of active epilepsy in southern Han Chinese.
Method: A door-to-door survey about epilepsy was conducted in communities identified by random cluster sampling among 20 villages and 3 communities of Yueyang city. A questionnaire for epilepsy based on the World Health Organization screening questionnaire was used.
Diagn Pathol
March 2013
Department of Urology, Hunan Children Hospital, Changsha 41007, China.
Background: Extra-adrenal paraganglioma of the retroperitoneum with metastasis to the vertebra is very rare. To our knowledge this is the first report of this kind of disease in the literature.
Case Presentation: Here, we present an oroginal case of paraganglioma of the retroperitoneum with metastasis to the abdominal vertebra in a 42-year-old female patient who was successfully treated by complete removal of the tumor and its metastasis.
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
November 2003
Intensive care unit of Hunan Children Hospital, Changsha, Hunan 410007, China.