11 results match your criteria: "Hunan Children Hospital[Affiliation]"

Evidence suggests that surgical procedures can effect the central nervous system and lead to changes in mood and behavior, rarely understood about the role of acute inflammation in promoting acute anxiety postoperatively. This study was designed to explore the possible mechanism of dexmedetomidine (DEX, a2-adrenergic receptor agonist) for reducing acute postoperative anxiety, which may be related to the activation of nuclear factor kappa B (NF-κB) and downstream signal pathway in the hippocampus. Experiments were conducted with rat, the elevated plus-maze and open field test were performed to evaluate anxiety-like behavior.

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The association of nutrient intake with epilepsy: A cross-sectional study from NHANES, 2013-2014.

Epilepsy Res

February 2024

Department of Pharmacy, Hunan Children Hospital, Changsha, Hunan 410007, China. Electronic address:

Background: Dietary nutrient supplements are helpful in the treatment of many diseases, but their effect on epilepsy is still controversial. This study aimed to evaluate the association between dietary intake of multiple nutrients and epilepsy.

Methods: A total of 3963 participants from the NHANES database were involved in this study.

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Background: Nasopharyngeal carcinoma (NPC) is a malignant tumor of epithelial origin in head and neck with high incidence rate in Southern China. C2orf40 has been identified as a tumor suppressor gene in many cancers. However, the roles of C2orf40 in nasopharyngeal carcinoma has not been studied.

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Background: Surgery results in systemic inflammation, which can affect the central nervous system, leading to changes in mood, emotion, and behavior. Our previous study has shown that compared to midazolam, dexmedetomidine premedication effectively decreased children's postoperative anxiety.

Aim: To investigate whether dexmedetomidine infusion before hernia repair alleviates postoperative systemic inflammation in children and whether postoperative anxiety may be associated with postoperative inflammation.

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The Anti-Inflammatory Effects of CXCR5 in the Mice Retina following Ischemia-Reperfusion Injury.

Biomed Res Int

December 2019

Aier School of Ophthalmology, Central South University, Aier Eye Institute, Changsha, Hunan, China.

Object: Retinal ischemia-reperfusion (I/R) injury is a common pathological process in many ophthalmic diseases; there are no effective therapeutic approaches available currently. Increasing evidence indicates that microglia mediated neuroinflammation plays an important role in the retinal I/R injury. In this study, we aimed to investigate the roles of chemokine receptor CXCR5 in the pathological process of retinal I/R injury model.

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Background: Perioperative anxiety is common in pediatric patients undergoing surgery.

Aims: The aim of this study was to determine whether an infusion of dexmedetomidine prior to hernia repair in children provides better postoperative anxiety outcomes that a preoperative infusion of midazolam.

Methods: Ninety 6-11-year-old children, who were scheduled to undergo elective hernia repair, were enrolled for this double-blind, randomized controlled trial.

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Article Synopsis
  • No studies have previously examined the use of kidneys from pediatric donors with severe Hand, Foot, and Mouth Disease (HFMD).
  • A retrospective analysis of six kidney transplant cases from four pediatric donors with severe HFMD was conducted, involving donors aged between 6 months and nearly 4 years and recipients aged 18 to 41.
  • Follow-up results showed that all recipients, except one, maintained normal kidney function, with 100% recipient survival and 83.3% allograft survival, and none exhibited symptoms related to HFMD.
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Scanning indels in the 5q22.1 region and identification of the TMEM232 susceptibility gene that is associated with atopic dermatitis in the Chinese Han population.

Gene

June 2017

Institute of Dermatology and Department of Dermatology of First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, China; Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, China, Hefei, Anhui, China; State key Laboratory Incubation Base of Dermatology, Anhui Medical University, Hefei, Anhui, China. Electronic address:

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease. The 5q22.1 region was found to have an association with AD in our previous genome-wide association study (GWAS).

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Prevalence and clinical characteristics of active epilepsy in southern Han Chinese.

Seizure

September 2014

Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China. Electronic address:

Purpose: To investigate the prevalence and clinical characteristics of active epilepsy in southern Han Chinese.

Method: A door-to-door survey about epilepsy was conducted in communities identified by random cluster sampling among 20 villages and 3 communities of Yueyang city. A questionnaire for epilepsy based on the World Health Organization screening questionnaire was used.

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Background: Extra-adrenal paraganglioma of the retroperitoneum with metastasis to the vertebra is very rare. To our knowledge this is the first report of this kind of disease in the literature.

Case Presentation: Here, we present an oroginal case of paraganglioma of the retroperitoneum with metastasis to the abdominal vertebra in a 42-year-old female patient who was successfully treated by complete removal of the tumor and its metastasis.

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