A multi-omics approach to unravel the interaction between heat and drought stress in the holobiont.

The impact of combined heat and drought stress was investigated in and compared to individual stresses to reveal additive effects and interactions. A combination of plant metabolomics and root and rhizosphere bacterial metabarcoding were used to unravel effects at the plant holobiont level. Hierarchical cluster analysis of metabolomics signatures pointed out two main clusters, one including heat and combined heat and drought, and the second cluster that included the control and drought treatments.

Configurational Field Analysis: a new approach to global field dynamics.

This paper advances the theory of Configurational Field Analysis (CFA) as a reconfiguration of Pierre Bourdieu's field theory, aiming to address the limitations of Global Field Theory in analyzing the complexities of global and transnational phenomena. While the concept of the Global Field extended Bourdieu's ideas to transnational and global arenas, it has been critiqued for its structural determinism, Eurocentrism, and its inability to fully capture the fluid, indeterminate, and contingent nature of global social dynamics. In response, this paper introduces social configurations as dynamic, relational constructs that emerge from specific historical and contextual conditions, rather than as fixed and universal structures.

Romantic Relationships Matter More to Men than to Women.

Women are often viewed as more romantic than men, and romantic relationships are assumed to be more central to the lives of women than to those of men. Despite the prevalence of these beliefs, some recent research paints a different picture. Using principles and insights based on the interdisciplinary literature on mixed-gender relationships, we advance a set of four propositions relevant to differences between men and women and their romantic relationships.

The older, the better: a comprehensive survey of soil organic carbon under commercial oil palm plantations.

Soil conditions of croplands are a frequent topic of scientific research. In contrast, less is known about large-scale commercial plantations of perennial crops such as oil palm. Oil palm is a globally important tropical commodity crop which contributes to both food and energy security due to its exceptional productivity.

Trends of mapping knowledge structure and themes of cancer sonodynamic therapy: a text-mining study.

Background: Sonodynamic therapy (SDT) is a non-invasive cancer treatment technique stemming from photodynamic therapy (PDT) and has garnered escalated interest among researchers in recent years. Numerous aspects of cancer SDT remain contentious, and the global research trajectory within this domain remains insufficiently explored. This study seeks to delineate the comprehensive knowledge framework, developmental trends, and pivotal research focal points concerning cancer SDT.

Species-specific responses of canopy greenness to the extreme droughts of 2018 and 2022 for four abundant tree species in Germany.

Germany experienced extreme drought periods in 2018 and 2022, which significantly affected forests. These drought periods were natural experiments, providing valuable insights into how different tree species respond to drought. The quantification of species-specific drought responses may help to identify the most climate-change-resilient tree species, thereby informing effective forest regeneration strategies.

Trajectories of episodic memory in midlife: Historical change from a cross-country perspective.

According to the Flynn effect, performance on cognitive ability tests has improved over the past decades. However, we know very little about whether such historical improvements generalize to middle-aged adults (aged 45-65) and differ across nations. We used harmonized data on episodic memory from nationally representative longitudinal panel surveys across a total of 16 countries (United States, Mexico, China, England, and countries in Continental, Mediterranean, and Nordic Europe).

Motor styles in action: Developing a computational framework for operationalization of motor distances.

Aside from some common movement regularities, significant inter-individual and inter-trial variation within the same individual exists in motor system output. However, there is still a lack of a robust and widely adopted solution for quantifying the degree of similarity between movements. We therefore developed an innovative approach based on the Procrustes transformation to compute 'motor distance' between pairs of kinematic data.

Gold nanoclusters AuAcCys normalize intracellular ROS without increasing cytoplasmic alarmin acHMGB1 abundance in human microglia and neurons.

This study focuses on the modulatory effects of gold nanoclusters with 25 gold atoms and 18 acetyl cysteines (AuAcCys) in human microglia, human iPSC-derived neurons and SH-SY5Y differentiated human neuronal cells. The combination of chemical, biological, and computational methods shows the well-retained viability of these human cells treated with AuAcCys, interactions between AuAcCys and transcription factor TFEB (computational approach), interactions between TFEB and HMGB1 (proximity ligation assay and molecular modeling using AlphaFold), modulation of the abundance and location of acHMGB1 by AuAcCys (immunocytochemistry), and the reduction of ROS in cells treated with AuAcCys (CellROX live imaging). These novel findings in human neural cells, particularly neurons, encourage further studies in experimental animal models of neurological disorders and/or human organoids to exploit the unique structural and photophysical properties of gold nanoclusters and to better understand their ability to modulate molecular mechanisms in human cells.

Molecular architecture of synaptic vesicles.

Synaptic vesicles (SVs) store and transport neurotransmitters to the presynaptic active zone for release by exocytosis. After release, SV proteins and excess membrane are recycled via endocytosis, and new SVs can be formed in a clathrin-dependent manner. This process maintains complex molecular composition of SVs through multiple recycling rounds.

Reliability and validity of the Game Addiction Scale in Malaysian Adolescents.

Objectives: Problematic gaming behavior has been an issue in many countries, raising the need for assessment tools. The Game Addiction Scale for Adolescents (GASA) by Lemmens et al. is widely used for assessing game addiction and has been adopted for use in various countries.

Photoisomerization Paths of α,ω-Diphenylpolyenes: Reaction Rate Dependence on Temperature, Excitation Wavelength, and Deuteration.

The photoisomerization rate of -stilbene (tS) and trans-trans-diphenylbutadiene (ttD) is studied in solution and compared to that in jet/gas. Rice-Ramsperger-Kassel-Marcus (RRKM) theory correctly predicts the tS rate in jet, = exp(-/) with = 1398 cm, and = 1.8 ps corresponding to frequency ν = 60 cm of the reactive mode, being the molecular temperature.

Susceptibility to online misinformation: A systematic meta-analysis of demographic and psychological factors.

Nearly five billion people use and receive news through social media and there is widespread concern about the negative consequences of misinformation on social media (e.g., election interference, vaccine hesitancy).

Data-sampled time-varying formation for singular multi-agent systems with multiple leaders.

The time-varying formation problem of singular multi-agent systems under sampled data with multiple leaders is investigated in this paper. Firstly, a data-sampled time-varying formation control protocol is proposed in the current study where the communication among followers merely occurred at sampling instants, which can save the controller communication energy significantly. Secondly, necessary and sufficient conditions for the feasibility of the formation function are provided.

Inkjet-Printed FASnPbI-Based Perovskite Solar Cells.

Metal halide perovskite solar cells (PSCs) have gained significant attention in thin-film photovoltaic research for their high power conversion efficiency (PCE) and facile fabrication processes. This study presents the use of inkjet printing to fabricate thin films of combinatorial mixed formamidinium tin-lead perovskites and evaluates their layer quality and device performance. Our findings demonstrate that incorporating Pb up to 50% into FASnI films enhances lattice stability.

Tactile mechanisms and afferents underlying the rat pup transport response.

Juvenile rodents and other altricial mammals react with calming, immobility, and postural modifications to parental pickup, a set of behaviors referred to as the transport response. Here, we investigate sensory mechanisms underlying the rat transport response. Grasping rat pups in anterior neck positions evokes strong immobility and folding up of feet, whereas more posterior grasping has lesser effects on immobility and foot position.

Augmentation of cognitive-behavioural therapy for obsessive-compulsive and anxiety disorders: a protocol for a systematic review and meta-analysis.

Introduction: While cognitive-behavioural therapy (CBT) for obsessive-compulsive disorder (OCD) and anxiety disorders (ADs) has been proven to be effective and is commonly recommended, a considerable proportion of patients remain symptomatic, do not respond to treatment or discontinue it. Thus, augmentation strategies aimed at enhancing CBT outcomes are essential to reduce the burden of OCD and ADs on patients and society. Various augmentation strategies for CBT in OCD and ADs have been investigated, yet it remains unclear if they show robust beneficial effects beyond first-line CBT.

Public attitudes towards social media field experiments.

The growing use of social media field experiments demands a rethink of current research ethics in computational social science and psychological research. Here, we provide an exploratory empirical account of key user concerns and outline a number of critical discussions that need to take place to protect participants and help researchers to make use of the novel opportunities of digital data collection and field studies. Our primary contention is that we need to elicit public perceptions to devise more up-to-date guidelines for review boards whilst also allowing and encouraging researchers to arrive at more ethical individual study design choices themselves.

Observed carbon decoupling of subnational production insufficient for net-zero goal by 2050.

Historically, economic growth has been closely coupled to carbon emissions responsible for climate change, but to stabilize global mean temperature, net-zero carbon emissions are necessary. Some economies have begun to reduce emissions while continuing to grow, but this decoupling is not fast enough to achieve global climate targets. Subnational climate actions seem to be crucial for the achievement of these targets.

Identification of a Specific Granular Marker of Zebrafish Eosinophils Enables Development of New Tools for Their Study.

Eosinophils control many aspects of the vertebrate innate immune response. They contribute to homeostasis, inflammatory conditions and defense against pathogens. With the varied functions of eosinophils, they have been found to play both protective and pathogenic roles in many diseases.

The Best DFT Functional Is the Ensemble of Functionals.

The development of better density functional theory (DFT) methods is one of the most active research areas, given the importance of DFT for ubiquitous molecular and materials simulations. However, this research primarily focuses on improving a specific exchange-correlation Kohn-Sham density functional. Here, a robust procedure is proposed for constructing transferable ensembles of density functionals that perform superior to any constituent individual density functional.