18 results match your criteria: "Humanitas University - Hunimed.[Affiliation]"

Objectives: To investigate students' experience with medical education alongside their mental and physical health since the onset of the COVID-19 pandemic across nine countries.

Methods: A cross-sectional online survey was distributed by local collaborators to 2,280 medical students across 148 medical schools in Brazil, Chile, Colombia, Germany, Italy, Japan, Mexico, Spain, and Venezuela using non-probability convenience sampling from June 22 to July 24, 2020. Students answered questions regarding teaching, internet use, COVID-19, physical and mental well-being.

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The global pandemic caused by coronavirus disease-2019 (COVID-19) disrupted both public and private life for many. Concerning medical students, practical teaching and classrooms were substituted with a virtual curriculum. However, how this new academic environment has affected students' health and lifestyles has yet to be studied.

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Background: Dermatochalasis of the upper eyelids (blepharochalasis) is a typical age-related change in the upper third of the face and a major concern for facial aesthetics. Nowadays both surgical and nonsurgical interventions are available for patients complaining of upper eyelid dermatochalasis. Although nonsurgical treatments are often easier to perform, if they are not performed correctly, complications may ensue and worsen the condition.

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Interactions between the splicing machinery and RNA polymerase II increase protein-coding gene transcription. Similarly, exons and splicing signals of enhancer-generated long noncoding RNAs (elncRNAs) augment enhancer activity. However, elncRNAs are inefficiently spliced, suggesting that, compared with protein-coding genes, they contain qualitatively different exons with a limited ability to drive splicing.

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Article Synopsis
  • The commitment of mesenchymal stem cells to become preadipocytes is influenced by hormones, triggering changes that are essential for their differentiation into mature adipocytes.
  • Research has identified Zc3h10 as a key regulatory factor during the early stages of adipogenesis; its depletion leads to disrupted protein synthesis and filamentous actin remodeling, harming mitochondrial function and metabolism.
  • Overexpression of Zc3h10 results in larger lipid droplets in mature adipocytes, highlighting its crucial role in promoting proper energy metabolism and lipid accumulation.
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The evolution of autologous breast reconstruction.

Breast J

November 2020

Reconstructive and Aesthetic Plastic Surgery School, Department of Medical Biotechnology and Translational Medicine BIOMETRA - Plastic Surgery Unit, Humanitas, Clinical and Research Hospital, University of Milan, Rozzano (Milan), Italy.

With breast cancer (BC) becoming more treatable, breast reconstruction has become an integral part of BC treatment. Nowadays, implant-based breast reconstruction is more common. However, there is a growing interest in autologous breast reconstruction due to the increasing awareness of implant-related complications.

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The evolution of breast prostheses.

Breast J

September 2020

Department of Medical Biotechnology and Translational Medicine BIOMETRA - Plastic Surgery Unit, Reconstructive and Aesthetic Plastic Surgery School, Humanitas Clinical and Research Hospital, University of Milan, Milan, Italy.

Every year approximately 1.5 million prostheses are implanted worldwide for breast augmentation and reconstructive indications. The modern breast implant as we know was released to the open market in 1963.

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Breast cancer (BC) is the most common female cancer worldwide and the second most common cause of cancer-related death in women. BC diagnosis and management have changed dramatically over the years. We recount the historic milestones that have brought the surgical management of breast cancer to its current state.

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Comment on "Unfiltered Nanofat Injections Rejuvenate Postburn Scars of Face".

Ann Plast Surg

October 2019

Plastic Surgery Unit MultiMedica Holding S.p.A. Reconstructive and Aesthetic Plastic Surgery School, University of Milan Sesto San Giovanni, Milan, Italy Plastic Surgery Unit Department of Medical Biotechnology and Translational Medicine BIOMETRA Reconstructive and Aesthetic Plastic Surgery School Humanitas Research HospitalUniversity of Milan, Milan, Italy. Plastic Surgery Unit Department of Medical Biotechnology and Translational Medicine BIOMETRA Reconstructive and Aesthetic Plastic Surgery School Humanitas Research Hospital University of Milan, Milan, Italy. Office of Medical Education Plastic Surgery Unit Humanitas Research Hospital Humanitas University, Milan, Italy. Humanitas University (Hunimed)Rozzano, Milan, Italy. Università degli Studi di MilanoMilan, Italy. Plastic Surgery Unit Department of Medical Biotechnology and Translational Medicine BIOMETRA Reconstructive and Aesthetic Plastic Surgery School Humanitas Research Hospital University of Milan, Milan, Italy.

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Accessibility of the genomic regulatory information is largely controlled by the nucleosome-organizing activity of transcription factors (TFs). While stimulus-induced TFs bind to genomic regions that are maintained accessible by lineage-determining TFs, they also increase accessibility of thousands of -regulatory elements. Nucleosome remodeling events underlying such changes and their interplay with basal positioning are unknown.

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Comment on: ‟Efficacy of autologous fat transfer for the correction of contour deformities in the breast: A systematic review and meta-analysis".

J Plast Reconstr Aesthet Surg

June 2019

Reconstructive and Aesthetic Plastic Surgery School, Department of Medical Biotechnology and Translational Medicine BIOMETRA - Plastic Surgery Unit, Humanitas Research Hospital, University of Milan, Rozzano, Milan, Italy.

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The two most relevant endoscopic treatable benign biliary diseases (BBD) are benign biliary strictures (BBSs) and biliary leaks (BLs), often associated with high morbidity. The most common endoscopic treatment for biliary strictures involves placement of multiple plastic stents (PSs), with or without balloon dilation, followed by planned exchange of the stents. Thus, there continues to be high interest in pursuing alternative endoscopic approaches that may achieve better results with fewer interventions.

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Article Synopsis
  • Cell type-specific enhancers and housekeeping promoters play crucial roles in regulating gene transcription in mammalian cells.
  • Recent findings highlight how specific DNA sequences help connect promoters with the right enhancers, influencing how genes are expressed.
  • Additionally, these sequence features can boost the activity of many regulatory elements, enhancing their overall function.
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