4,062 results match your criteria: "Human Herpesvirus 6"
Open Forum Infect Dis
December 2024
[This corrects the article DOI: 10.1093/ofid/ofae501.].
View Article and Find Full Text PDFJ Neurol
December 2024
Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany.
Background And Objectives: The impact of viral infections on disease susceptibility and progression has predominantly been studied in patients with relapse-onset MS (RMS). Here, we determined immune responses to ubiquitous viruses in patients with primary progressive MS (PPMS).
Methods: Antibody responses to Epstein-Barr virus (EBV), specifically to the latent EBV nuclear antigen 1 and the lytic viral capsid antigen VCA, human herpesvirus 6 (HHV-6), human cytomegalovirus (HCMV), and measles virus were determined in a cohort of 68 PPMS patients with a mean follow-up of 8 years and compared with 66 healthy controls matched for sex and age.
J Sports Med Phys Fitness
December 2024
Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan -
Background: Persistent physical fatigue (PPhF) accompanying daily intensive training often results in underperformance. While salivary secretory immunoglobulin A (SIgA) has been traditionally used as an immunological marker, salivary human herpesvirus 6 and/or 7 (HHV-6/7) have recently been presented as "microbiological" markers of PPhF. This study aimed to examine the monthly variabilities of salivary HHV-6/7 levels and the difference with SIgA along the training periodization.
View Article and Find Full Text PDFAm J Forensic Med Pathol
December 2024
Sci Rep
November 2024
Third Department of Breast Surgery, Peking University Cancer Hospital Yunnan Hospital, The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital, Kunming, 650118, China.
Background: There may be potential associations between various pathogens, antibody immune responses, and breast cancer (BC), but the specific mechanisms and causal relationships remain unclear.
Methods: First, multiple Mendelian randomization (MR) methods were used for univariable MR analysis to explore potential causal relationships between 34 antibody immune responses (related to 12 pathogens), 46 antibody immune responses (related to 13 pathogens), antibody responses post-COVID-19 vaccination, 731 immune cell types, and various BC subtypes (including overall BC, ER-positive, ER-negative, Luminal A, Luminal B, Luminal B HER2-negative, HER2-positive, and triple-negative BC). The primary results were then subjected to reverse MR analysis, heterogeneity testing using Cochran's Q, and horizontal pleiotropy testing.
Sci Rep
November 2024
Duke-NUS Medical School, Singapore, Singapore.
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare severe cutaneous adverse drug reaction associated with multi-organ involvement and long-term sequelae. Human herpesviridae species reactivation has been observed, however, risk factors for reactivation and its impact on the clinical course and outcomes is unclear. We aimed to explore the impact of viral reactivation on DRESS on clinical outcomes and to identify potential risk factors for reactivation.
View Article and Find Full Text PDFCurr Neurol Neurosci Rep
November 2024
Neuroscience Department, Meyer Children's Hospital IRCCS, Viale Pieraccini 24, 50139, Florence, Italy.
Purpose Of Review: This review examines the role of different viral infections in epileptogenesis, with a focus on Herpesviruses such as Human Herpesvirus 6 (HHV-6) and Epstein Barr Virus (EBV), Flaviviruses, Picornaviruses, Human Immunodeficiency Virus (HIV), Influenzavirus and Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2).
Recent Findings: A growing literature on animal models, such as the paradigmatic Theiler's murine encephalomyelitis virus (TMEV) model, and clinical investigations in patients with epilepsy have started to elucidate cellular mechanisms implicated in seizure initiation and development of epilepsy following viral infections. A central role of neuroinflammation has emerged, with evidence of activation of the innate and adaptive immunity, dysregulation of microglial and astrocytic activity and production of multiple cytokines and other inflammatory mediators.
J Virol
December 2024
Institute of Virology, Freie Universität Berlin, Berlin, Germany.
Unlabelled: Despite the availability of bacterial artificial chromosome (BAC) systems for human herpesvirus 6A (HHV-6A), reconstitution of infectious viruses is very challenging and time consuming. In this study, we developed approaches to improve the reconstitution process and enhance virus replication to overcome these technical challenges. Using dimethyl sulfoxide and exonuclease V, we significantly increased the efficiency of BAC transfections into JJHan T cells.
View Article and Find Full Text PDFNeurol Sci
November 2024
Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Biomolecules
October 2024
The Institute of Microbiology and Virology of the Riga Stradiņš University Science Hub, LV-1067 Riga, Latvia.
Clin Pract
September 2024
2nd Department of Anaesthesiology and Intensive Care, Medical University of Warsaw, 02-097 Warsaw, Poland.
Expert Opin Drug Saf
October 2024
Department of Acupuncture and Moxibustion, Foshan Hospital of Traditional Chinese Medicine, Foshan, Guangdong, China.
Iran J Allergy Asthma Immunol
May 2024
Daneshmand Pathology Laboratory, Arak, Iran.
Biomed Rep
December 2024
Department of Medical Technology, Faculty of Allied Health Sciences, Burapha University, Chonburi 20131, Thailand.
Major depressive disorder (MDD) is a global health concern with a complex etiology involving genetic, environmental and infectious factors. The exact cause of MDD remains unknown. The present study explored the association between genetic factors, human herpesvirus 6 (HHV-6) and MDD.
View Article and Find Full Text PDFCurr Opin Infect Dis
December 2024
Vaccine and Infectious Disease Division.
Rheumatol Int
December 2024
Department of Clinical Immunology and Allergology, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.
J Clin Oncol
December 2024
Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.
Ann Hematol
September 2024
Department of Pediatrics (Children Hematological Oncology), Childhood Hematological Oncology and Birth Defects Laboratory, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Open Forum Infect Dis
September 2024
Department of Infectious Diseases, Frankston Hospital, Peninsula Health, Victoria, Australia.
Surg Neurol Int
August 2024
Division of Pediatric Neurosurgery, Children's Hospital Orange County, Orange, California, United States.
Bone Marrow Transplant
December 2024
Seattle Children's Research Institute and Department of Pediatrics, University of Washington, Seattle, WA, USA.
Sports Med Health Sci
September 2024
Pauley Heart Center, Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, 23298-0204, USA.
Int Immunopharmacol
December 2024
Spine Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People's Republic of China. Electronic address:
J Clin Med
August 2024
Faculty of General Medicine, Department of Infectious Diseases, "Carol Davila" University of Medicine and Pharmacy, Dionisie Lupu Street No. 37, 010458 Bucharest, Romania.
Discov Med
August 2024
Department of Biomedical Engineering, Faculty of Engineering and Life Sciences, Biruni University, 34015 Istanbul, Turkiye.