Association of Depression With Handgrip Strength and Muscle Mass in Young and Middle-Aged American Adults From NHANES 2011-2014: A Cross-Sectional Study.

Purpose: To investigate relationship between depression and handgrip strength (HGS) and appendicular lean mass (ALM) in Young and middle-aged adults.

Design: Cross-sectional study.

Setting: Data from participants aged 20-59 from the 2011-2014 National Health and Nutrition Examination Survey.

Association of EDN levels in patients with asthma and correlation with FEV%: A meta-analysis.

Eosinophil-derived neurotoxin (EDN), an eosinophil degranulation product, is a good biomarker for eosinophilic inflammation of the airway. Several articles have shown that EDN levels are higher in patients with asthma than in controls, and EDN levels are correlated with the percentage of predicted forced expiratory volume in the first second (FEV%) in patients with asthma. Their results were inconclusive.

Diagnostic value of IL-6 for patients with asthma: a meta-analysis.

Background: IL-6 is a pleotropic cytokine that acts as a pro-inflammatory mediator and acute-phase response inducer, but has also been reported to possess anti-inflammatory properties. The objective of this study was to assess the validity of serum IL-6 test for diagnosis of asthma.

Methods: A literature search was conducted using PubMed, Embase, and Cochrane library from January 2007 to March 2021 to identify relevant studies.

Quantitative proteomics profiling of plasma from children with asthma.

A lack of validated blood diagnostic markers presents an obstacle to asthma control. The present study sought to profile the plasma proteins of children with asthma and to determine potential biomarkers. Plasma samples from children in acute exacerbation (n = 4), in clinical remission (n = 4), and from healthy children (n = 4, control) were analyzed using a tandem mass tag (TMT)-labeling quantitative proteomics and the candidate biomarkers were validated using liquid chromatography-parallel reaction monitoring (PRM)/mass spectrometry (MS) with enzyme-linked immunosorbent assay (ELISA).