4,580 results match your criteria: "Huffman; and Harvard Medical School Celano[Affiliation]"

Article Synopsis
  • - The research emphasizes the need for greater transmission capacities in the upcoming 6G communication era, pushing both academia and industry to explore higher parts of the electromagnetic spectrum to avoid spectrum resource limits.
  • - A novel visible light laser communication (VLLC) system utilizing red, green, and blue (RGB) laser diodes is introduced, achieving a 100-meter free-space transmission using a time domain hybrid huffman coding technique.
  • - The VLLC system successfully recorded data transmission rates of 16.852 Gbps for red, 14.442 Gbps for green, and 15.755 Gbps for blue channels, leading to a total rate of 47.049 Gbps while keeping the bit error rate under the
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A computer-generated hologram compression and transmission system is designed. The system uses a hybrid neural network based on quantum compensation to compress and decompress computer-generated holograms and uses a quantization method and Huffman coding to encode the compressed holograms for transmission. The receiving side decodes and decompresses the data stream to obtain the recovered hologram, which can be used to reconstruct the original object information for 3D image display.

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Introduction: Nurses working in the emergency department experience high rates of burnout. The purpose of this study was to determine job-related factors affecting the well-being of emergency nurses.

Methods: In this cross-sectional study data were collected through multiple methods.

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The multicenter Necrotizing Enterocolitis Surgery Trial compared initial peritoneal drainage with laparotomy among infants with extremely low birth weight and surgical necrotizing enterocolitis or intestinal perforation. In this post hoc analysis of trial data, initial drainage was associated with adverse respiratory outcomes, both in hospital and through 2 years corrected age.

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Article Synopsis
  • - This study focuses on tackling hypertension in Peru through a hybrid research design testing a community health worker (CHW)-led program, aiming to improve blood pressure control within the national primary care system in Puno.
  • - A total of 1068 adults with hypertension will be recruited and randomly assigned to either usual care or a 12-month intervention, which includes home-based monitoring, medication support, and lifestyle counseling.
  • - The trial will evaluate clinical effectiveness (like changes in blood pressure) and implementation outcomes (such as program acceptance and cost-effectiveness), providing valuable insights for future health strategies in Peru and similar low- to middle-income countries (LMICs).
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Objective: This pilot trial examined a Physical Activity and Symmetry (PAS) intervention focused on common deficits of physical inactivity and joint loading asymmetry following total knee arthroplasty (TKA).

Design: Participants (n ​= ​60) were enrolled during routine physical therapy (PT) following TKA and randomized to the PAS intervention or an attention (ATT) control group. The PAS intervention included physical activity counseling and balance exercise to address joint loading symmetry; content was delivered during 2 sessions at the end of routine PT plus supplemental sessions 4-weeks and 8-weeks following PT.

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Negative Pressure Wound Therapy with Instillation for Periprosthetic Infection after Breast Reconstruction: A Systematic Review.

Plast Reconstr Surg Glob Open

November 2024

From the Department of Surgery/Division of Plastic and Reconstructive Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Ill.

Background: Periprosthetic infection after breast reconstruction is not uncommon and can result in loss of the implant pocket and negative patient outcomes. Management of these infections typically involves removal of the prosthesis, treatment with antibiotics, and delayed reconstruction upon infection resolution. The impact of adjunctive use of negative pressure wound therapy with instillation and dwell (NPWTi-d) on breast pocket salvage rates, time to implant reinsertion, and related outcomes was examined.

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Background: A polypill containing all 4 classes of guideline-directed medical therapy for heart failure with reduced ejection fraction (HFrEF) has been proposed to change the heart failure treatment paradigm. The acceptability, appropriateness, and feasibility of a HFrEF polypill-based strategy are unknown. The purpose of this study was to elicit patients' and providers' priorities in the design of HFrEF polypills.

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Usability of Light-Linking Technology for Infusion Line Identification: A Simulation Study With ICU Nurses.

J Infus Nurs

November 2024

Author Affiliations: Department of Implementation Science (Huffman and Munn), Center for Experiential and Applied Learning (Saunders), and Department of Biostatistics and Data Science (Russell), Wake Forest University School of Medicine (Gonzales), Winston-Salem, North Carolina; Center for Nursing Research (Huffman) and Comprehensive Cancer Center (Butcher), Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina; Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina (Hampton).

Critical care nurses are faced with increasing task loads due to increasing patient complexity. In addition to this complexity, most critical care patients have a maze of infusion and monitoring lines that must be navigated when administering medications. Task load is escalated when a nurse must identify an injection port and administer a medication rapidly.

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A single-center retrospective chart review of percutaneous PNS for treatment of chronic shoulder pain.

Interv Pain Med

September 2024

SPR Therapeutics, 22901 Millcreek Blvd, Suite 500, Cleveland, OH, 44122, USA.

Objective: The present IRB-approved retrospective chart review describes the use of a 60-day PNS treatment for shoulder pain at a single center in 60 total consecutive patients.

Background: Chronic shoulder pain affects an increasing number of patients per year and is especially prevalent in elderly populations. Percutaneous peripheral nerve stimulation (PNS) treatment targeting the nerves of the shoulder has been shown to reduce pain in prospective clinical studies and in analysis of real-world data.

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Retinal ganglion cell-derived semaphorin 6A segregates starburst amacrine cell dendritic scaffolds to organize the mouse inner retina.

Development

November 2024

The Solomon H. Snyder Department of Neuroscience, Johns Hopkins Kavli Neuroscience Discovery Institute, The Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.

To form functional circuits, neurons must settle in their appropriate cellular locations, and then project and elaborate neurites to contact their target synaptic neuropils. Laminar organization within the vertebrate retinal inner plexiform layer (IPL) facilitates pre- and postsynaptic neurite targeting, yet the precise mechanisms underlying establishment of functional IPL subdomains are not well understood. Here, we explore mechanisms defining the compartmentalization of OFF and ON neurites generally, and OFF and ON direction-selective neurites specifically, within the developing mouse IPL.

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Blood biomarkers of trans-fatty acid intake among Nigerian adults in the Federal Capital Territory: a cross-sectional study.

Am J Clin Nutr

January 2025

Cardiovascular Research Unit, University of Abuja, and University of Abuja Teaching Hospital, Gwagwalada, Abuja, Nigeria; Department of Internal Medicine, Faculty of Clinical Sciences, University of Abuja, Abuja, Nigeria.

Background: Intake of trans-fatty acids (TFAs) is an established risk factor for cardiovascular disease. In April 2023, Nigeria passed regulations limiting TFA content in foods, fats, and oils, but the current level of TFA exposure in the Nigerian population is unknown.

Objectives: To quantify trans-fatty acid (TFA) biomarkers in dried blood spots from Nigerian adults in the Federal Capital Territory before policy enforcement, establish baseline levels for future evaluations, assess subgroup variations by demographic and socioeconomic factors, and compare TFA levels with data from 30 countries worldwide.

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A search for the exclusive hadronic decays W^{±}→π^{±}γ, W^{±}→K^{±}γ, and W^{±}→ρ^{±}γ is performed using up to 140  fb^{-1} of proton-proton collisions recorded with the ATLAS detector at a center-of-mass energy of sqrt[s]=13  TeV. If observed, these rare processes would provide a unique test bench for the quantum chromodynamics factorization formalism used to calculate cross sections at colliders. Additionally, at future colliders, these decays could offer a new way to measure the W boson mass through fully reconstructed decay products.

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Article Synopsis
  • - The ATLAS experiment at the LHC conducted a search for long-lived particles (LLPs) using a large dataset (140 fb^{-1}) from proton-proton collisions at 13 TeV, focusing on LLPs with masses from 5 to 55 GeV that decay within the inner detector.
  • - The study considered scenarios where LLPs are produced from exotic Higgs boson decays and models involving axionlike particles (ALPs).
  • - No significant findings above expected background levels were detected, leading to the establishment of upper limits on various production rates involving the Higgs boson and the top quark related to LLPs and ALPs.
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Anterior cable reconstruction using subpectoral biceps tenodesis with biceps transfer in rotator cuff tears: a surgical technique.

JSES Rev Rep Tech

November 2024

Department of Orthopaedic Surgery, Rothman Orthopaedics Florida at AdventHealth, Orlando, FL, USA.

Massive rotator cuff tears constitute approximately 20% of all rotator cuff tears. Poor tissue quality or significant retraction can lead to failure of the repair. The anterior rotator cuff cable is essential in transmitting force to the proximal humerus and serves as the main load-bearing structure within the supraspinatus.

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The proposed Sensor Data Encryption with Compression (SEC) system is presented as an innovative solution for sensor data processing, aiming to achieve optimal efficiency while improving security and adaptability by integrating robust cryptography with advanced compression techniques. The system's objective is to create a reliable framework for managing sensitive sensor data by effectively tackling challenges in data processing through a balanced combination of strong cryptography and sophisticated compression methods. The SEC system utilizes advanced encryption and compression techniques, including the scrambling of Burrows-Wheeler Transform (BWT), Move-to-Front (MTF) encoding, Run-Length Encoding (RLE), and Huffman coding, to attain exceptional compression efficiency while maintaining data integrity.

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DNA is considered one of the most attractive storage media because of its excellent reliability and durability. Early encoding schemes lacked flexibility and scalability. To address these limitations, we propose a combination of static mapping and dynamic encoding, named "Galaxy" encoding.

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Distinct chemical structures inhibit the CEMIP hyaluronidase and promote oligodendrocyte progenitor cell maturation.

J Biol Chem

December 2024

Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, Oregon, USA. Electronic address:

Growing evidence supports pathogenic roles for chronically elevated hyaluronidase activity in numerous conditions. Elevated expression of one such hyaluronidase, the Cell Migration Inducing and hyaluronan binding Protein (CEMIP), has been implicated in the pathogenesis and progression of several cancers as well as demyelinating diseases in the central nervous system (CNS). Developing effective and selective CEMIP inhibitors could therefore have efficacy in treating a variety of conditions where CEMIP is chronically elevated.

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Article Synopsis
  • The study investigates the associated production of Higgs and W bosons, focusing on how the relative signs of the Higgs couplings to W and Z bosons impact the process.
  • Two specific searches were conducted using large amounts of collision data from the LHC to analyze different coupling scenarios: one for opposite-sign couplings and another for same-sign (standard model-like) couplings.
  • The results significantly exclude the opposite-sign coupling hypothesis and set a strict upper limit on the production rate of this process compared to standard model predictions.
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Objective: Caloric restriction (CR) is known to enhance insulin sensitivity and reduce the risk of metabolic disorders; however, its molecular mechanisms are not fully understood. This study aims to elucidate specific proteins and pathways responsible for these benefits.

Methods: We examined adipose tissue from participants in the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy Phase 2 (CALERIE 2) study, comparing proteomic profiles from individuals after 12 and 24 months of CR with baseline and an ad libitum group.

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Background: The World Health Organization HEARTS Technical Package is a widely implemented global initiative to improve the primary care management of cardiovascular disease risk factors. The study's objective is to report outcomes from a pilot implementation trial of integrated hypertension and diabetes management based on the HEARTS model in Guatemala.

Methods: We conducted a single-arm pilot implementation trial over 6 months from October 2023 to May 2024 in 11 Guatemalan Ministry of Health primary care facilities in two districts.

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Inferring post-transcriptional regulation within and across cell types in human testis.

bioRxiv

October 2024

Departments of Bioengineering, Biology, Chemistry and Chemical Biology, Single Cell Proteomics Center, Northeastern University, Boston, MA 02115, USA.

Article Synopsis
  • Researchers quantified protein abundance in 5,883 single cells from human testis using advanced mass spectrometry methods to better understand protein regulation beyond just RNA levels.
  • They developed a Bayesian model to distinguish between biological variations and technical factors affecting protein and RNA abundance in a dataset of 29,709 cells, covering 3,861 gene products.
  • The study found that about 28% of the gene products showed significant differences between protein and RNA levels, with specific functions like spermatogenesis regulated post-transcriptionally and associated with unique cell-type specific modifications.
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Objectives The objective of the study was to measure food security among Syrian refugees residing in urban and rural areas in Florida. Women's education, English proficiency, and nutrition knowledge were assessed to indicate their effects on food security in this population. Methods One-on-one interview questionnaires were administered to Syrian refugee households residing in Florida (n=80: n=43 in rural areas and n=37 in urban areas).

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Positive-ion laser desorption/ionization (LDI) of fullerenes contained in soot as produced by the Krätschmer-Huffman process delivers a wide range of fullerene molecular ions from C to above C. Here, the collision cross section (CCS) values of those fullerene molecular ions are determined using a trapped ion mobility-quadrupole-time-of-flight (TIMS-Q-TOF) instrument. While CCS values in the range from C to C are already known with high accuracy, those of ions from C onward had yet to be determined.

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